Identification and disruption of the gene encoding the K+-activated acetaldehyde dehydrogenase of Saccharomyces cerevisiae

FEMS Microbiology Letters

Volumn 164, Issue 1, 1998, Pages 29-34

  Tessier, Wayne D ^a   Meaden, Philip G ^b   Dickinson, Francis M ^a   Midgley, Melvin ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

^b HERIOT WATT UNIVERSITY   (United Kingdom)

Author keywords

Acetaldehyde dehydrogenase; Aldehyde dehydrogenase family; Ethanol metabolism; Protein purification; Saccharomyces cerevisiae

Indexed keywords

ALDEHYDE DEHYDROGENASE; MITOCHONDRIAL ENZYME; POTASSIUM ION;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GROWTH; ENZYME ACTIVITY; GENE DELETION; GENE DISRUPTION; GENE MAPPING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ALDEHYDE OXIDOREDUCTASES; AMINO ACID SEQUENCE; GENES, FUNGAL; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); SACCHAROMYCES CEREVISIAE;

EID: 0032124855     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(98)00192-X     Document Type: Article

References (19)

1. +-linked aldehyde dehydrogenases. Rev. Esp. Fisiol. 33, 135-142.
2. Seegmiller, J.E. (1953) Triphosphopyridine nucleotide-linked dehydrogenase from yeast. J. Biol. Chem. 201, 629-637.
3. Seegmiller, J.E. (1955) TPN-linked aldehyde dehydrogenase from yeast. Methods Enzymol. 1, 511-514.
4. Jacobson, M.K. and Bernofsky, C. (1974) Mitochondrial acetaldehyde dehydrogenase from Saccharomyces cerevisiae. Biochim. Biophys. Acta 305, 277-291.
5. 2+-activated acetaldehyde dehydrogenase. Yeast 13, 1319-1327.
6. Flikweert, M.T., Van Der Zanden, L., Janssen, W.M.T.M., Steensma, H.Y., Van Dijken, J.P. and Pronk, J.T. (1996) Pyruvate decarboxylase: an indispensable enzyme for growth of Saccharomyces cerevisiae on glucose. Yeast 12, 247-257.
7. Saigal, D., Cunningham, S.J., Farres, J. and Weiner, H. (1991) Molecular cloning of the mitochondrial aldehyde dehydrogenase gene of Saccharomyces cerevisiae by genetic complementation. J. Bacteriol. 173, 3199-3208.
8. Chalmers, R.M., Keen, J.N. and Fewson, C.A. (1991) Comparison of benzyl alcohol dehydrogenases and benzaldehyde dehydrogenases from the benzyl alcohol and mandelate pathways in Acinetobacter calcoaceticus and from the TOL-Plasmid encoded toluene pathway in Pseudomonas putida; N-terminal amino acid sequences, amino acid compositions and immunological cross-reactions. Biochem. J. 273, 99-107.
9. Larsson, N., Norbeck, J., Karlsson, H., Karlsson, K.A. and Blomberg, A. (1997) Identification of two-dimensional gel electrophoresis resolved yeast proteins by matrix-assisted laser desorption ionisation mass spectrometry. Electrophoresis. 18, 418-423.
10. Saccharomyces Genome Database. URL: http://genome-www.stanford.edu/Saccharomyces/.
11. Sikorski, R.S. and Hieter, P. (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122, 19-28.
12. Baudin, A., Ozier-Kalogeropoulos, O., Denouel, A., Lacroute, F. and Cullin, C. (1993) A simple and efficient method for direct gene replacement in Saccharomyces cerevisiae. Nucleic Acids Res. 21, 3329-3330.
13. Wightman, P., Quain, D.E. and Meaden, P.G. (1996) Analysis of production brewing strains of yeast by DNA fingerprinting. Lett. Appl. Microbiol. 22, 4673-4680.
14. Bostian, K.A. and Betts, G.F. (1978) Rapid purification and properties of potassium-activated aldehyde dehydrogenase from Saccharomyces cerevisiae. Biochem. J. 173, 773-786.
15. Clark, J.F. and Jakoby, W.B. (1970) Yeast aldehyde dehydrogenase. J. Biol. Chem. 245, 6065-6072.
16. 2+-aldehyde dehydrogenase of Saccharomyces cerevisiae. Biochem. J. 315, 393-399.
17. Dalziel, K. (1962) Kinetic studies of liver alcohol dehydrogenase. Biochem. J. 84, 244-255.
18. Miralles, V.J. and Serrano, R. (1995) A genomic locus in Saccharomyces cerevisiae with four genes up-regulated by osmotic stress. Mol. Microbiol. 17, 653-662.
19. Lutstorf, U. and Megnet, R. (1968) Multiple forms of ADH in Saccharomyces cerevisiae. Arch. Biochem. Biophys. 126, 933-944.