Predictive study by molecular modeling to promote specific probes of glutamate receptors, using methylated cyclic glutamic acid derivatives (trans- and cis-ACPD). Comparison with specific agonists

Journal of Chemical Information and Computer Sciences

Volumn 38, Issue 4, 1998, Pages 742-760

  Evrard Todeschi, Nathalie ^a   Gharbi Benarous, Josyane ^a   Larue, Valéry ^a,b   Girault, Jean Pierre ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b UNIVERSITÉ PARIS 13   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 1-AMINO-1,3-DICARBOXYCYCLOPENTANE; AMINO ACID RECEPTOR STIMULATING AGENT; CYCLOLEUCINE; DRUG DERIVATIVE; GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; COMPUTER SIMULATION; CONFORMATION; DRUG DESIGN; DRUG EFFECT; HUMAN; METABOLISM; METHYLATION; MOLECULAR PROBE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

COMPUTER SIMULATION; CYCLOLEUCINE; DRUG DESIGN; EXCITATORY AMINO ACID AGONISTS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; METHYLATION; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR PROBES; RECEPTORS, GLUTAMATE; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 0032112831     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci9802023     Document Type: Article

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