Conformational analysis of a Chlamydia-specific disaccharide α-Kdo-(2→8)-α-Kdo-(2→O)-allyl in aqueous solution and bound to a monoclonal antibody: Observation of intermolecular transfer NOEs

Journal of Biomolecular NMR

Volumn 12, Issue 1, 1998, Pages 123-133

  Sokolowski, Tobias ^a   Haselhorst, Thomas ^a   Scheffler, Karoline ^a   Weisemann, Rüdiger ^b   Kosma, Paul ^c   Brade, Helmut ^d   Brade, Lore ^d   Peters, Thomas ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b Bruker Analytik GmbH   (Germany)

^c UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^d RESEARCH CENTER BORSTEL   (Germany)

Author keywords

HMQC trNOESY; Kdo; Monoclonal antibody; QUIET trNOESY; trNOESY; trRoESY

Indexed keywords

CHLAMYDIA;

3 DEOXYMANNO OCT 2 ULOSONIC ACID (2 8) 3 DEOXYMANNO OCT 2 ULOSONIC ACID (2 O) ALLYL; 3-DEOXYMANNO-OCT-2-ULOSONIC ACID-(2-8)-3-DEOXYMANNO-OCT-2-ULOSONIC ACID-(2-O)-ALLYL; DISACCHARIDE; EPITOPE; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; WATER;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CHLAMYDIA; CONFORMATION; HUMAN; IMMUNOLOGY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; PATHOGENICITY; SOLUTION AND SOLUBILITY;

ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; CARBOHYDRATE CONFORMATION; CHLAMYDIA; DISACCHARIDES; EPITOPES; HUMANS; LIPOPOLYSACCHARIDES; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SOLUTIONS; WATER;

EID: 0032110303     PISSN: 09252738     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016047602190     Document Type: Article

References (22)

1. Arepalli, S.R., Glaudemans, C.P.J., Daves, G.D., Kovac, P. and Bax, A. (1995) J. Magn. Reson., B106, 195-198.
2. Asensio, J.L., Canada, F.J. and Jimenez-Barbero, J. (1995) Eur. J. Biochem., 233, 618-630.
3. Bock, K., Thomsen, J.U., Kosma, P., Christian, R., Holst, O. and Brade, H. (1992) Carbohydr. Res., 229, 213-224.
4. Brade, H., Brabetz, W., Brade, L., Holst, O., Löbau, S., Lucakova, M., Mamat, U., Rozalski, A., Zych, K. and Kosma, P. (1997) J. Endotoxin Res., 4, 67-84.
5. Emsley, L. and Bodenhausen, G. (1992) J. Magn. Reson., 97, 135-148.
6. Fu, Y., Baumann, M., Kosma, P., Brade, L. and Brade, H. (1992) Infect. Immun., 60, 1314-1321.
7. Hwang, T.-L. and Shaka, A.J. (1992) J. Am. Chem. Soc., 114, 3157-3159.
8. Kosma, P., Bahnmüller, R., Schulz, G. and Brade, H. (1990) Carbohydr. Res., 208, 37-50.
9. Lian, L. Y., Barsukov, I. L., Sutcliffe, M. J., Sze, K. H. and Roberts, G. C. K. (1994) Methods Enzymol, 239, 657-700.
10. Massefski, W. and Redfield, A.G. (1988) J. Magn. Reson., 78, 150-155.
11. Mikol, V., Kosma, P. and Brade, H. (1994) Carbohydr. Res., 263, 35-42.
12. Moseley, H.N.B., Lee, W., Arrowsmith, C.H. and Krishna, N.R. (1997) Biochemistry, 36, 5239-5299.
13. Ni, F. (1994) Prog. NMR Spectrosc., 26, 517-606.
14. Peters, T., Meyer, B., Stuike-Prill, R., Somorjai, R. and Brisson, J.-R. (1993) Carbohydr. Res., 238, 49-73.
15. Peters, T. and Pinto, B.M. (1996) Curr. Opin. Struct. Biol, 6, 710-720.
16. Scheffler, K., Ernst, B., Katopodis, A., Magnani, J. L., Wang, W.T., Weisemann, R. and Peters, T. (1995) Angew. Chem., Int. Ed. Engl., 34, 1841-1844.
17. Scherf, T. and Anglister, J. (1993) Biophys. J., 64, 754-761.
18. Stuike-Prill, R. and Meyer, B. (1991) Eur. J. Biochem., 194, 903-919.
19. Vincent, S.J.F., Zwahlen, C., Post, C.B., Burgner, J.W. and Bodenhausen, G. (1997) Proc. Natl. Acad. Sci. USA, 94, 4383-4388.
20. Weimar, T., Harris, S. L., Pitner, J. B., Bock, K. and Pinto, B. M. (1995) Biochemistry, 34, 13672-13680.
21. Weimar, T., Imberty, A., Perez, S. and Peters, T. (1997) Theochem., 395/396, 297-311.
22. Zwahlen, C., Vincent, S.J.F., Di Bari, L., Levitt, M.H. and Bodenhausen, G. (1994) J. Am. Chem. Soc., 116, 362-368.