Effect of Duodenal Components of the Refluxate on Development of Esophageal Neoplasia in Rats

Journal of Gastrointestinal Surgery

Volumn 2, Issue 4, 1998, Pages 350-355

  Yamashita, Yoshinori ^a   Homma, Kiichi ^a   Kako, Norio ^a   Clark, Geoffery W B ^a   Smyrk, Thomas C ^a   Hinder, Ronald A ^b   Adrian, Thomas E ^a   DeMeester, Tom R ^c   Mirvish, Sidney S ^d  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DIMETHYL 4 NITROSOMORPHOLINE; CARCINOGEN; DNA; N-NITROSO-2,6-DIMETHYLMORPHOLINE; NITROSAMINE;

ANEUPLOIDY; ANIMAL; ARTICLE; BILE; BILE REFLUX; CHEMICALLY INDUCED DISORDER; COCARCINOGENESIS; DUODENUM; ESOPHAGUS; ESOPHAGUS TUMOR; FLOW CYTOMETRY; GENETICS; INTESTINE SECRETION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; PANCREAS JUICE; PAPILLOMA; PATHOLOGY; PHYSIOLOGY; RAT; SECRETION; SPRAGUE DAWLEY RAT; SQUAMOUS CELL CARCINOMA;

ANEUPLOIDY; ANIMALS; BILE; BILE REFLUX; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; COCARCINOGENESIS; DNA, NEOPLASM; DUODENUM; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; FLOW CYTOMETRY; INJECTIONS, INTRAPERITONEAL; INTESTINAL SECRETIONS; MALE; NITROSAMINES; PANCREATIC JUICE; PAPILLOMA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032107110     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1091-255X(98)80074-7     Document Type: Article

References (24)

1. Attwood SEA, DeMeester TR, Bremner CG, Barlow AP, Hinder RA. Alkaline gastroesophageal reflux: Implications in the development of complications in Barrett's columnar-lined lower esophagus. Surgery 1989;106:764-770.
2. DeMeester TR, Attwood SEA, Smyrk TC, Therkildsen DH, Hinder RA. Surgical therapy in Barrett's esophagus. Ann Surg 1990;212:528-542.
3. Stein HS, Hoeft S, DeMeester TR. Functional foregut abnormalities in Barrett's esophagus. J Thorac Cardiovasc Surg 1993;105:107-111.
4. Vaezi MF, Richter JE. Synergism of acid and duodenogastroesophageal reflux in complicated Barrett's esophagus. Surgery 1995;117:699-704.
5. Attwood SEA, Smyrk TC, DeMeester TR, Mirvish SS, Stein HJ, Hinder RA. Duodenoesophageal reflux and the development of esophageal adenocarcinoma in rats. Surgery 1992; 111:503-510.
6. Pera H, Cardesa A, Bombi JA, Ernst H, Pera C, Mohr U. Influence of esophagojejunostomy on the induction of adenocarcinoma of the distal esophagus in Sprague-Dawley rats by subcutaneous injection of 2,6-dimethylnitrosomorpholine. Cancer Res 1989;49:6803-6808.
7. Clark GWB, Smyrk TC, Mirvish SS, Anselmino M, Yamashita Y, Hinder RA, DeMeester TR. Effect of gastroduodenal juice and dietary fat on the development of Barrett's esophagus and esophageal neoplasia: An experimental rat model. Ann Surg Oncol 1994;1:252-261.
8. Lijinsky W, Taylor HW. Increased carcinogenicity of 2,6-dimethylnitrosomorpholine compared with nitrosomorpholine in rats. Cancer Res 1975;35:2123-2125.
9. Lijinsky W, Reubner MD. Comparative carcinogenicity of two isomers of N-nitroso-2,6-dimethylmorpholine in guinea pigs. Cancer Lett 1981;14:7-11.
10. Weil GS. Tables for convenient calculation of median effective dose (LD50 or ED50) and instructions on their use. Biometrics 1952;8:249-263.
11. Bloom SR, Long RG, eds. Radioimmunoassay of Gut Regulatory Peptides. London: WB Saunders, 1982.
12. Hedley DW. Flow cytometry using paraffin-embedded tissue. Cytometry 1989;10:229-241.
13. Shearman DJC, Arnott SJ, Finlayson NDC, Pearson JG. Carcinoma of the esophagus after gastric surgery. Lancet 1970;21:581-582.
14. Maeta M, Koga S, Shimizu T, Matsui K. Possible association between gastrectomy and subsequent development of esophageal cancer. J Surg Oncol 1990;44:2-24.
15. Kranendonk SE. Reflux oesophagitis: An experimental study in rats [Dissertation]. Rotterdam: Erasmus University of Rotterdam, 1980.
16. Levrat M, Lambert R, Kirshbaum G. Esophagitis produced by reflux of duodenal contents in rats. Am J Dig Dis 1962; 7:564-573.
17. Kivilaakso E, Fromm D, Silen W. Effect of bile salt and related compounds on isolated esophageal mucosa. Surgery 1980;87:280-285.
18. Lillemoe KD, Johnson LF, Harmon JW. Alkaline esophagitis: A comparison of the ability of components of gastroduodenal contents to injure the rabbit esophagus. Gastroenterology 1983;85:621-628.
19. Segawa M. Reflux of gastroduodenal juice and esophageal carcinogenesis in rats. Jpn J Gastroenterol Surg 1993;26:971-978.
20. Seto Y, Kobori O, Shimizu E, Morioka Y. The role of alkaline reflux in esophageal carcinogenesis induced by N-amyl-N-methylnitrosamine in rats. Int J Cancer 1991;49:758-763.
21. Pera M, Trastek VF, Carpenter HA, Fernandez PL, Cardesa A, Mohr U, Pairolero PC. Influence of pancreatic and biliary reflux on the development of esophageal carcinoma. Ann Thoracic Surg 1993;55:1386-1393.
22. Ushigome S, Spjut HJ, Noon GP. Extensive dysplasia and carcinoma in situ of oesophageal epithelium. Cancer 1967; 20:1023-1029.
23. 3. Mud HJ, Kranendonk SE, Obertop H, Van Houton H, Westhoek DL. Active trypsin and reflux oesophagitis: An experimental study in rats. Br J Surg 1982;69:269-272.
24. Sasaki I, Suzuki Y, Naito H, Funayama Y, Kamiyama Y, Takahashi M, Matsuo T, Fukushima K, Matsuno S, Sato T. Effect of the treatment of reflux esophagitis after gastrectomy: An experimental study in rats and a pilot clinical study. Biomed Res 1989;10(Suppl 1):167-173.