Single-dose methotrexate for unruptured ectopic pregnancy

International Journal of Gynecology and Obstetrics

Volumn 61, Issue 3, 1998, Pages 253-259

  Lecuru, F ^a,b   Robin, F ^a,b   Bernard, J P ^a,b   Maizan De Malartic, C ^a,b   Mac Cordick, C ^a,b   Boucaya, V ^a,b   Taurelle, R ^a,b  

^a Hopital Boucicaut   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Ectopic pregnancy; Effectiveness; Laparoscopy; Methotrexate; Prospective comparison; Selection

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; METHOTREXATE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL EXAMINATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; ECTOPIC PREGNANCY; FEMALE; FOLLOW UP; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; OUTPATIENT; PERITONEAL FLUID; PRIORITY JOURNAL; PROSPECTIVE STUDY; SALPINGOSTOMY;

EID: 0032103391     PISSN: 00207292     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7292(98)00038-1     Document Type: Article

References (23)

1. Carson SA, Buster J Current concepts in ectopic pregnancy. N Engl J Med. 329:1993;1147-1181.
2. Ory S, Villanueva A, Sand P, Tamura R Conservative treatment of ectopic pregnancy with methotrexate. Am J Obstet Gynecol. 154:1986;1299-1306.
3. Stovall T, Ling F, Gray L Single-dose methotrexate for treatment of ectopic pregnancy. Obstet Gynecol. 77:1991;754-757.
4. Stovall TG, Ling FW Single dose methotrexate: An expanded clinical trial. Am J Obstet Gynecol. 168:1993;1759-1765.
5. Chapron C, Querleu D, Crépin G Laparoscopic treatment of ectopic pregnancies: a one hundred cases study. Eur J Obstet Gynecol. 41:1991;187-190.
6. Oettinger M, Odeh M, Tarazova L, Snitkovski T, Ophir E β-HCG concentration in peritoneal fluid and serum in ectopic and intrauterine pregnancy. Acta Obstet Gynecol Scand. 74:1995;212-215.
7. Lécuru F, Taurelle R, Viens-Bitker C, Robin F Cost of unruptured ectopic pregnancy treatment: comparison of laparoscopy and methotrexate injection. Gynaecol Endosc. 5:1996;25-28.
8. Rosen DJ, Ben-Nun I, Arbel Y, Altaras MM, Goldberger SB, Beyth Y Transvaginal ultrasonographic quantitative assessment of accumulated cul de sac fluid. Am J Obstet Gynecol. 166:1992;542-544.
9. Tanaka T, Hayashi H, Kutsuzawa T, Fujimoto S, Ichinoe K Treatment of interstitial ectopic pregnancy with methotrexate: report of a successful case. Fertil Steril. 37:1982;851-852.
10. Creinin M, Washington A Cost of ectopic pregnancy management: surgery versus methotrexate. Fertil Steril. 60:1993;963-969.
11. Stika CS, Anderson L, Frederiksen MC Single dose methotrexate for the treatment of ectopic pregnancy: Northwestern Memorial Hospital three-year experience. Am J Obstet Gynecol. 174:1996;1840-1848.
12. Hajenius P, Engelsbel S, Mol Bet al. Randomised trial of systemic methotrexate versus laparoscopic salpingostomy in tubal pregnancy. Lancet. 350:1997;774-779.
13. Glock JL, Johnson JV, Brumsted JR Efficacy and safety of single dose systemic methotrexate in the treatment of ectopic pregnancy. Fertil Steril. 62:1994;716-721.
14. Dwarakanath L, Mascarenhas L, Penketh R, Newton J Persistent ectopic pregnancy following conservative surgery for tubal pregnancy. Br J Obstet Gynecol. 103:1996;1021-1024.
15. Yao M, Tulandi T Current status of surgical and non surgical management of ectopic pregnancy. Fertil Steril. 67:1997;421-423.
16. Henry MA, Gentry WL Single injection of methotrexate for treatment of ectopic pregnancies. Am J Obstet Gynecol. 171:1994;1584-1587.
17. Hoppe D, Bekkar B, Nager C Single dose systemic methotrexate for the treatment of persistent ectopic pregnancy after conservative surgery. Obstet Gynecol. 83:1994;51-54.
18. Fernandez H, Lelaidier C, Thouvenez V, Frydman R The use of a pretherapeutic predictive score to determine inclusion criteria for the non surgical treatment of ectopic pregnancy. Hum Reprod. 6:1991;995-998.
19. Yao M, Tulandi T, Kaplow M, Patch Smith A A comparison of methotrexate versus laparoscopic surgery for the treatment of ectopic pregnancy: a cost analysis. Hum Reprod. 11:1996;2762-2766.
20. Lécuru F, Robin F, Maizan de Malartic C, Mac-Cordick C, Boucaya V, Taurelle R. Direct costs of single dose methotrexate for treatment of unruptured ectopic pregnancy: prospective comparison with laparoscopy. Fertil Steril (submitted for publication).
21. Querleu D, Chapron C Complications of gynecologic laparoscopic surgery. Curr Opin Obstet Gynecol. 7:1995;257-261.
22. Brown D, Felker R, Stovall T, Emerson D, Ling F Serial endovaginal sonography of ectopic pregnancies treated with methotrexate. Obstet Gynecol. 77:1991;406-409.
23. Horrigan T, Fanning J, Marcotte M Methotrexate pneumonitis after systemic treatment for ectopic pregnancy. Am J Obstet Gynecol. 176:1997;714-715.