A randomized, double-blind, dose-response study of ondansetron in the prevention of postoperative nausea and vomiting

Journal of Clinical Anesthesia

Volumn 10, Issue 4, 1998, Pages 314-320

  Dershwitz, Mark ^a,b   Conant, Jeffrey A ^a   Chang, YuChiao ^a,b   Rosow, Carl E ^a,b   Connors, Patricia M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

5 HT3 antagonists; Dose response study; Emesis; Nausea and vomiting, postoperative; Ondansetron

Indexed keywords

DIAZEPAM; DROPERIDOL; ISOFLURANE; MIDAZOLAM; MUSCLE RELAXANT AGENT; NITROUS OXIDE; ONDANSETRON; OPIATE; PROPOFOL;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; GENERAL ANESTHESIA; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; NAUSEA; PATIENT SATISFACTION; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; VOMITING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIEMETICS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MIDDLE AGED; NAUSEA; ONDANSETRON; PAIN MEASUREMENT; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; SEROTONIN ANTAGONISTS; SURVIVAL RATE; VOMITING;

EID: 0032102383     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-8180(98)00035-X     Document Type: Article

References (5)

1. Dershwitz M, Rosow CE, Di Biase PM, Joslyn AF, Sanderson PE: Ondansetron is effective in decreasing postoperative nausea and vomiting. Clin Pharmacol Ther 1992;52:96-101.
2. McKenzie R, Sharifi-Azad S, Dershwitz M, Miguel R, Joslyn AF, Tantisira B: A randomized, double-blind pilot study examining the use of intravenous ondansetron in the prevention of postoperative nausea and vomiting in female inpatients. J Clin Anesth 1993;5:30-6.
3. Pearman MH: Single dose intravenous ondansetron in the prevention of postoperative nausea and vomiting. Anaesthesia 1994; 49(suppl):11-15.
4. Pueyo FJ, Carrascosa F, Lopez L, Iribarren MJ, Garcia-Pedrajas, Saez A: Combination of ondansetron and droperidol in the prophylaxis of postoperative nausea and vomiting. Anesth Analg 1996;83:117-22.
5. McKenzie R, Uy NT, Riley TJ, Hamilton DL: Droperidol/ondansetron combination controls nausea and vomiting after tubal banding. Anesth Analg 1996;83:1218-22.