Identification of a dynamic intracellular reservoir of CD86 protein in peripheral blood monocytes that is not associated with the Golgi complex

Journal of Immunology

Volumn 160, Issue 11, 1998, Pages 5390-5396

  Smyth, Christine ^a   Logan, Grant ^a   Weinberger, Ron P ^b   Rowe, Peter B ^a   Alexander, Ian E ^b   Smythe, Jason A ^a  

^a CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

^b CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; NOCODAZOLE;

ARTICLE; CANCER RADIOTHERAPY; CONTROLLED STUDY; GOLGI COMPLEX; HUMAN; HUMAN CELL; MONOCYTE; NUCLEOTIDE SEQUENCE; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; TUMOR IMMUNITY;

ANTIGENS, CD; ANTIGENS, CD4; ANTIGENS, CD80; ANTIGENS, CD86; B-LYMPHOCYTES; CLONE CELLS; GOLGI APPARATUS; HELA CELLS; HUMANS; INTRACELLULAR FLUID; LYMPHOCYTE ACTIVATION; MACROPHAGE-1 ANTIGEN; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MICROTUBULES; MONOCYTES; MUROMONAB-CD3; T-LYMPHOCYTES; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0032101949     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Dalgleish, A. G., and M. Browning, eds. 1996. Tumor Immunology; Immunotherapy and Cancer Vaccines. Cambridge University Press, Cambridge, U.K.
2. Freeman, G. J., A. S. Freeman, J. M. Segil, G. Lee, J. F. Whitman, and L. M. Nadler. 1989. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J. Immunol. 143:2714.
3. Gimmi, C. D., G. J. Freeman, J. G. Gribben, K. Sugita, A. S. Freeman, C. Morimoto, and L. M. Nadler. 1991. B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc. Natl. Acad. Sci. USA 88:6575.
4. Nabavi, N., G. J. Freeman, A. Gault, D. Godfrey, L. M. Nadler, and L. H. Glimcher. 1992. Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression. Nature 360:266.
5. + T cells by B7-transfected melanoma cells. Science 259:368.
6. Hathcock, K. S., G. Laszlo, H. B. Dickler, J. Bradshaw, P. Linsley, and R. J. Modes. 1993. Identification of an alternative CTLA-4 ligand costimulatory for T-cell activation. Science 262:905.
7. Freeman, G. J., F. Borriello, R. J. Hodes, H. Reiser, K. S. Hathcock, G. Laszlo, A. J. McKnight, J. Kim, L. Du, D. B. Lombard, G. S. Gray, L. M. Nadler, and A. H. Sharpe. 1993. Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. Science 262:907.
8. Freeman, G. J., J. G. Gribben, V. A. Boussiotis, J. W. Ng, V. A. Restivo, L. A. Lombard, G. S. Gray, and L. M. Nadler. 1993. Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 262:909.
9. Azuma, M., D. Ito, H. Yagita, K. Okumura, J. H. Phillips, L. L. Lannier, and C. Somoza. 1993. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366:76.
10. Engel, P., J. G. Gribben, G. J. Freeman, L-J. Zhou, Y. Nozawa, M. Abe, L. M. Nadle,. H. Wakasa, and T. F. Tedder. 1994. The B7-2(B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. Blood 84:1402.
11. Freeman, G. J., G. S. Gray, C. D. Gimmi, D. B. Lombard, L-J. Zhou, M. White, J. D. Fingeroth, J. G. Gribben, and L. M. Nadler. 1991. Structure, expression, and T-cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. J. Exp. Med. 174:625.
12. Hathcock, K. S., G. Laszlo, C. Pucillo, P. Linsley, and R. Modes. 1994. Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J. Exp. Med. 180:631.
13. Chen, L., S. Ashe, W. A. Brady, I. Hellström, K. E. Hellström, J. A. Ledbelter, P. McGowan, and P. S. Linsley. 1992. Costimulation of antitumor immunity by the B7 counter receptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 71:1093.
14. Baskar, S., S. Ostrand-Rosenberg, N. Nabavi, L. M. Nadler, G. J. Freeman, and L. H. Glimcher. 1993. Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules. Proc. Natl Acad. Sci. USA 90:5687.
15. Li, Y., P. McGowan, I. Hellström, K. E. Hellström, and L. Chen. 1994. Costimulation of tumor-reactive CD4 and CD8 T lymphocytes by B7, a natural ligand for CD28, can be used to treat established mouse melanoma. J. Immunol. 153:421.
16. Mann, R., R. C. Mulligan, and D. Baltimore. 1983. Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell 33:153.
17. Miller, A. D., and G. J. Rosman. 1989. Improved retroviral vectors for gene transfer and expression. BioTechniques 7:980.
18. Miller, A. D., D. G. Miller, J. V. Garcia, and C. M. Lynch. 1993. The use of retroviral vectors for gene transfer and expression. Methods Enzymol. 217:581.
19. Shevzov, G., P. Gunning, P. L. Jeffrey, C. Temm-Grove, D. M. Helfman, J. J-C. Lin, and R. P. Weinberger. 1997. Tropomyosin localisation reveals distinct populations of microfilaments in neurites and growth cones. Mol. Cell. Neurosci. 8:439.
20. Kanof, M. E. 1991. Isolation of T-cells using resetting procedures. In Current Protocols in Immunology, Vol 2. J. E. Coligan ed. Wiley, New York, unit 7.2.1.
21. Milich, D. R., P. S. Linsley, J. L. Hughs, and J. E. Jones. 1994. Soluble CTLA-4 can suppress autoantibody production and elicit long term unresponsiveness in a novel transgenic model. J. Immunol. 153:429.
22. Krummel, M. F., and J. P. Allison. 1995. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182:459.
23. Bluestone, J. A. 1997. Is CTLA-4 a master switch for peripheral T cell tolerance? J. Immunol 158:1989.
24. Kiener, P. A., P. M. Davis, B. M. Rankin, S. J. Klebanoff, J. A. Ledbetter, G. C. Starling, and W. C. Liles. 1997. Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation. J. Immunol. 159:1594.
25. Kind, P. C., G. M. Kelley, H. J. Fryer, C. Blakemore, and S. Hockfield. 1997. Phospholipase C-β1 is present in the botrysome, an intermediate compartment-like organelle, and is regulated by visual experience in cat visual cortex. J. Neurosci. 17:1471.