Molecular specificity of a medium chain Acyl-CoA synthetase for substrates and inhibitors: Conformational analysis

Biochemical Pharmacology

Volumn 55, Issue 11, 1998, Pages 1769-1775

  Kasuya, Fumiyo ^a   Yamaoka, Yumiko ^a   Igarashi, Kazuo ^a   Fukui, Miyoshi ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Amino acid conjugation; Inhibition; Medium chain acyl CoA synthetase; Steric conformation; Substrate specificity

Indexed keywords

AROMATIC CARBOXYLIC ACID; BENZOIC ACID DERIVATIVE; DECANOIC ACID DERIVATIVE; DIFLUNISAL; HEXANOIC ACID; HYDRATROPIC ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE; MEDIUM CHAIN FATTY ACID; NALIDIXIC ACID; PHENYLACETIC ACID DERIVATIVE; SALICYLIC ACID;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONJUGATION; DETOXIFICATION; ELECTRICITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SPECIFICITY; HYDROPHOBICITY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

ACETIC ACIDS; ANIMALS; BENZOATES; CATTLE; COENZYME A LIGASES; ENZYME INHIBITORS; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0032101666     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00640-0     Document Type: Article

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