Feasibility of sterilizing traditional Chinese medicines by gamma- irradiation

Radiation Physics and Chemistry

Volumn 52, Issue 1-6, 1998, Pages 53-58

  Fang, Xingwang ^a   Wu, Jilan ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Chemical clearance; Evaluation; Sterilization; Traditional Chinese medicine; Wholesomeness

Indexed keywords

ALKALOID; ANTHRAQUINONE DERIVATIVE; DRUG ADDITIVE; FLAVONOID; HERBACEOUS AGENT; STARCH; TERPENE DERIVATIVE;

CHINESE MEDICINE; CONFERENCE PAPER; DRUG CONTAMINATION; DRUG FORMULATION; DRUG MANUFACTURE; GAMMA IRRADIATION; GLYCYRRHIZA; HONEY; RADIATION DOSE; RADIATION STERILIZATION;

EID: 0032101659     PISSN: 0969806X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-806X(98)00073-5     Document Type: Conference Paper

References (18)

1. Boess, C. and Boegl, K. W. (1996) Influence of radiation treatment on pharmaceuticals - a review: alkaloids, morphine derivatives, and antibiotics. Drug Develop. Indust. Pharmacy, 22, 495-529.
2. Buter, J. and Hoey, B. M. (1986) The apparent inhibition of superoxide dismutase activity by quinones. J. Free Rad. Biol. Med., 2, 77-81.
3. Cai, Z. L. (1993) The radiation chemistry of baicalin aqueous and ethanol solutions. Ph.D. Dissertation, Peking University.
4. Cai, Z. L.; He, Y. K. and Wu, J. L. (1996) Study of baicalin scavenging hydroxyethyl peroxyl radicals by radiolysis of aerated ethanol-baicalin system. Radiat. Phys. Chem., 47, 869-871.
5. Chen, C. (1996) Radiolysis of glycyrrhizic acid in aqueous and ethanolic solutions. Ph.D. Dissertation, Peking University.
6. 2O saturated aqueous solution. A product and pulse radiolysis study. Radiat. Phys. Chem., in press.
7. Dauphin, J. -F. and Saint-Lebe, L. R. (1977) Radiation chemistry of carbohydrates. In Radiation Chemistry of Major Food Components. pp. 131-185. Elias, P. S. and Cohen, A. J. (eds.), Elsevir, Amsterdam.
8. Deng, W. G.; He, Y. K., Wu, J. L. and Fang, X. W. (1997) Radiolysis of rutin in Aerated Ethanolic solution. Radiat. Phys. Chem., in press.
9. Gopal, N. G. S. (1995) Radiation sterilization and treatment of medical products: current practices, regulations and standards, IAEA Consultants' Meeting "Training Guidelines for Industrial Sterilization", Jerusalem.
10. Jacobs, G. P. (1995) A review of the effects of gamma radiation on pharmaceutical materials. J. Radn. Sterilization, 1(4), 327-344.
11. Li, S. (1988) The radiation chemistry of baicalin aqueous solution. M. Sc. Dissertation, Peking University.
12. Qin, L. Y. (1991) The radiolysis products of alizarin and radiation chemistry of 1,8-dihydroxyanthraquionone aqueous solution. M. Sc. Dissertation, Peking University.
13. 60Co-γ radiation sterilization of Chinese herbal medicine. Chinese Institute of Pharmaceutics and Biological Products Inspection.
14. Wen, L. (1993) γ-Radiolysis of gentiopicroside, an effective component of Chinese herb radix asterig. M. Sc. Dissertation, Peking University.
15. Wu, J. L.; Zhang, X. J., Yuan, R. Y. and Y. K. He (1995) Radiolysis of herbs. Radiat. Phys. Chem., 46, 275-279.
16. Yuan, R. Y., Zhou, Y. R., Sun, H. and Wu, J. L. (1988) Studies on the radiolysis of anthraquinones in rhubarb. Beijing Daxue Xuebao (Ziran Kexue Ban), 24(2), 158-162. (in Chinese)
17. Yuan, R. Y., Zhang, Z. G., Zhu, Y., He, Y. K. and Wu, J. L. (1989) γ-Radiolysis of corydalic B aqueous solution. Zhongguo Hekexue Yu Gongcheng, 9, 359-362. (in Chinese)
18. Zhang, X. J.; Wu, J. L., Cai, Z. L., Yao, S. D.; Zuo, Z. H. and Lin, N. Y. (1995) Kinetics and products of OH radical addition to baicalin. Radiat. Res., 142, 227-231.