Sexual behavior in male rats after radiofrequency or dopamine-depleting lesions in nucleus accumbens

Pharmacology Biochemistry and Behavior

Volumn 60, Issue 2, 1998, Pages 585-592

  Liu, Yian Cheng ^a   Sachs, Benjamin D ^a   Salamone, John D ^a  

^a And Biobehavioral Sci Grad D ^*  (United States)

Author keywords

Copulation; Dopamine; Male rats; Noncontact erection; Nucleus accumbens; Sexual arousal

Indexed keywords

APOMORPHINE; DEXAMPHETAMINE; DOPAMINE; OXIDOPAMINE;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; AROUSAL; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; COPULATION; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PENIS ERECTION; PRIORITY JOURNAL; RADIOFREQUENCY RADIATION; RAT; SEXUAL BEHAVIOR; YAWNING;

ANIMALS; APOMORPHINE; CENTRAL NERVOUS SYSTEM STIMULANTS; COPULATION; DEXTROAMPHETAMINE; DOPAMINE; DOPAMINE AGONISTS; FEMALE; MALE; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; OXIDOPAMINE; PENILE ERECTION; RADIATION INJURIES, EXPERIMENTAL; RADIO WAVES; RATS; SEXUAL BEHAVIOR, ANIMAL; SYMPATHOLYTICS; YAWNING;

EID: 0032101180     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00022-7     Document Type: Article

References (46)

1. Argiolas A., Melis M.R., Mauri A., Gessa G.L. Paraventricular nucleus lesion prevents yawning and penile erection induced by apomorphine and oxytocin but not ACTH in rats. Brain Res. 421:1987;349-352.
2. Barr B., Leipheimer R.E. Bilateral lesions of the nucleus accumbens do not inhibit copulatory behavior of male rats. Soc. Neurosci. Abstr. 19:1993;589.
3. Cador M., Taylor J.R., Robbins T.W. Potentiation of the effects of reward-related stimuli by dopaminergic-dependent mechanisms in the nucleus accumbens. Psychopharmacology (Berlin). 104:1991;377-385.
4. Canteras N.S., Simerly R.B., Swanson L.W. Organization of projections from the medial nucleus of the amygdala. A PHAL study in the rat J. Comp. Neurol. 360:1995;213-245.
5. Cousins M.S., Sokolowski J.D., Salamone J.D. Different effects of nucleus accumbens and ventrolateral striatal dopamine depletions on instrumental response selection in the rat. Pharmacol. Biochem. Behav. 46:1993;943-951.
6. Damsma G., Pfaus J.G., Wenkstern D.G., Phillips A.G., Fibiger H.C. Sexual behavior increases dopamine transmission in the nucleus accumbens and striatum of male rats. Comparison with novelty and locomotion Behav. Neurosci. 106:1992;181-191.
7. Dourish C.T., Hutson P.H. Bilateral lesions of the striatum induced with 6-hydroxydopamine abolish apomorphine-induced yawning in rats. Neuropharmacology. 24:1985;1051-1055.
8. Edwards D.A., Davis A.B. Deafferentation of the olfactory bulbs of male rats reduces erection to remote cues from females. Physiol. Behav. 62:1997;145-149.
9. Everitt B.J. Sexual motivation. A neural and behavioral analysis of the mechanisms underlying appetitive and copulatory responses of male rats Neurosci. Biobehav. Rev. 14:1990;217-232.
10. Fumero B., Fernandez-Vera J.R., Gonzalez-Mora J.L., Mas M. Changes in monoamine turnover in forebrain areas associated with masculine sexual behavior. A microdialysis study Brain Res. 662:1994;233-239.
11. Gower A.J., Berendsen H.H.G., Princen M.M., Broekkamp C.L.E. The yawning-penile erection syndrome as a model for putative dopamine autoreceptor activity. Eur. J. Pharmacol. 103:1984;81-89.
12. Heimer L., Zahm D.S., Churchill L., Kalivas P.W., Wohltmann C. Specificity in projection patterns of accumbal core and shell in the rat. Neuroscience. 41:1991;89-125.
13. Holmes G.M., Holmes D.G., Sachs B.D. An IBM-PC based data collection system for recording rodent sexual behavior and for general event recording. Physiol. Behav. 44:1988;825-828.
14. Hull E.M. Dopaminergic influences on male rat sexual behavior. Micevych P.E., Hammer R.P. Neurobiological effects of sex steroid hormones. 1995;234-253 Cambridge University Press, New York.
15. Hull E.M., Weber M.S., Eaton R.C., Dua R., Markowski V.P., Lumley L., Moses J. Dopamine receptors in the ventral tegmental area affect motor, but not motivational or reflexive, components of copulation in male rats. Brain Res. 554:1991;72-76.
16. Kelly P.H., Seviour P.W., Iversen S.D. Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Res. 94:1975;507-522.
17. Kondo, Y; Sachs, B. D.; Sakuma, Y.: Importance of the medial amygdala in rat penile erection evoked by remote stimuli from estrous females. Behav. Brain Res. (in press).
18. Liu Y.-C., Salamone J.D., Sachs B.D. Lesions in medial preoptic area and bed nucleus of stria terminalis. Differential effects on copulatory behavior and noncontact erection in male rats J. Neurosci. 17:1997;5245-5253.
19. Louilot A., Gonzalez-Mora J.L., Guadalupe T., Mas M. Sex-related olfactory stimuli induce a selective increase in dopamine release in the nucleus accumbens of male rats. A voltammetric study. Brain Res. 553:1991;313-317.
20. Lynch M.R., Carey R.J. Environmental stimulation promotes recovery from haloperidol-induced extinction of open field behavior in rats. Psychopharmacology (Berlin). 92:1987;206-209.
21. Mas M., Gonzalez-Mora J.L., Louilot A., Solé C., Guadalupe T. Increased dopamine release in the nucleus accumbens of copulating male rats as evidenced by in vivo voltammetry. Neurosci. Lett. 110:1990;303-308.
22. Mas, M.; Gonzalez-Mora, J. L.: Monitoring brain neurotransmitter release during sociosexual interactions. In: Gonzalez-Mora, J. L.; Borges, R.; Mas, M., eds. Moritoring molecules in neuroscience. Proceedings of the 7th international conference on in vivo methods. Tenerife: University of La Laguna; 1996:77-78.
23. Meisel, R. L.; Sachs, B. D.: The physiology of male sexual behavior. In: Knobil, E.; Neill, J. D., eds. The physiology of reproduction, 2nd ed., vol. 2. New York: Raven Press; 1994:3-105.
24. Melis M.R., Argiolas A., Gessa G.L. Apomorphine-induced penile erection and yawning. Site of action in brain Brain Res. 415:1987;98-104.
25. Mogenson G.J. Limbic-motor integration. Epstein A.N., Morrison A.R. Progress in psychobiology and physiological psychology, vol. 12. 1987;117-170 Academic Press, Inc, London.
26. Mogilnicka E., Klimek V. Drugs affecting dopamine neurons and yawning behavior. Pharmacol. Biochem. Behav. 7:1977;303-305.
27. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 2:1986;Academic Press, San Diego.
28. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 3:1996;Academic Press, San Diego.
29. Pfaus J.G., Damsma G., Nomikos G.G., Wenkstern D.G., Blaha C.D., Phillips A.G., Fibiger H.C. Sexual behavior enhances central dopamine transmission in the male rat. Brain Res. 530:1990;345-348.
30. Pfaus J.G., Phillips A.G. Role of dopamine in anticipatory and consummatory aspects of sexual behavior in the male rat. Behav. Neurosci. 105:1991;727-743.
31. Phillips A.G., Pfaus J.G., Blaha C.D. Dopamine and motivated behavior. Insights provided by in vivo analysis Willner P., Scheel-Krüger J. The mesocorticolimbic dopamine system. From motivation to action:1991;199-224 John Wiley & Sons, London.
32. Pleim E.T., Matochik J.A., Barfield R.J., Auerbach S.B. Correlation of dopamine release in the nucleus accumbens with masculine sexual behavior in rats. Brain Res. 524:1990;160-163.
33. Robbins T.W., Cador M., Taylor J.R., Everitt B.J. Limbic-striatal interactions in reward-related processes. Neurosci. Biobehav. Rev. 13:1989;155-162.
34. Sachs B.D. Placing erection in context. The reflexogenic-psychogenic dichotomy reconsidered Neurosci. Biobehav. Rev. 19:1995;211-224.
35. Sachs B.D. Context-sensitive variation in the regulation of erection. Bancroft J. The Pharmacology of sexual function and dysfunction. 1995;97-108 Elsevier, Amsterdam.
36. Sachs B.D. Penile erection in response to remote cues from females. Albino rats severely impaired relative to pigmented strains Physiol. Behav. 60:1996;803-808.
37. Sachs, B. D.: Erection evoked in male rats by airborne scent from estrous females. Physiol. Behav. (in press).
38. Sachs B.D., Akasofu K., Citron J.H., Daniels S.D., Natoli J.H. Noncontact exposure to estrous females evoked penile erection in rats. A rodent model of psychogenic erection Physiol. Behav. 55:1994;1073-1079.
39. Salamone J.D. Behavioral pharmacology of dopamine system. A new synthesis Willner P., Scheel-Krüger J. The mesocorticolimbic dopamine system. From motivation to action:1991;599-613 John Wiley & Sons, London.
40. Salamone J.D. Complex motor and sensorimotor functions of striatal and accumbens dopamine. Involvement in instrumental behavior processes Psychopharmacology (Berlin). 107:1992;160-174.
41. Salamone J.D. The actions of neuroleptic drugs on appetitive instrumental behaviors. Iversen L.L., Iversen S.D., Snyder S.H. Handbook of psychopharmacology. 1987;575-608 Plenum Press, New York.
42. Salamone J.D., Cousins M.S., Snyder B.J. Behavioral functions of nucleus accumbens dopamine. Empirical and conceptual problems with the anhedonia hypothesis Neurosci. Biobehav. Rev. 21:1997;341-359.
43. Serra G., Collu M., Gessa G.L. Dopamine receptors mediating yawning. Are they autoreceptors? Eur. J. Pharmacol. 120:1986;187-192.
44. Wenkstern D., Pfaus J.G., Fibiger H.C. Dopamine transmission increases in the nucleus accumbens of male rats during their first exposure to sexually receptive female rats. Brain Res. 618:1993;41-46.
45. West C.H.K., Clancy A.N., Michael R.P. Enhanced responses of nucleus accumbens neurons in male rats to novel odors associated with sexually receptive females. Brain Res. 585:1992;49-55.
46. Zahm D.S., Brog J.S. On the significance of subterritories in the "accumbens" part of the rat ventral striatum. Neuroscience. 50:1992;751-767.