Potential serotonergic interactions with the anxiolytic-like effects of calcium channel antagonists

Pharmacology Biochemistry and Behavior

Volumn 60, Issue 2, 1998, Pages 365-369

  El Ganouni, S ^a   Tazi, A ^b   Hakkou, F ^b  

^a IR2M Laboratory   (Morocco)

^b HASSAN II UNIVERSITY   (Morocco)

Author keywords

5 HT(1A) agonists; Anxiolytics; Calcium channel antagonists; Ipsapirone; Nifedipine; Nimodipine; Novel environment

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; DIAZEPAM; IPSAPIRONE; NIFEDIPINE; NIMODIPINE; SEROTONIN 1A AGONIST;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENTIATION; FLUID INTAKE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONINERGIC SYSTEM; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; CALCIUM CHANNEL BLOCKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; ENVIRONMENT; MALE; NIFEDIPINE; NIMODIPINE; PYRIMIDINES; RATS; RATS, WISTAR; SEROTONIN; SEROTONIN AGONISTS;

EID: 0032100504     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00014-8     Document Type: Article

References (32)

1. Bolger G.T., Lesieur P., Basile A.S., Skolnick P. Modulation of neurotransmitter metabolism by dihydropyridine calcium channel ligands in mouse brain. Brain Res. 438:1988;101-107.
2. Boullin D.J., Grahame-Smith D.G. Behaviour effects of calcium channel bloquers suggesting a central serotoninergic mechanism. Br. J. Pharmacol. 92:1987;607p.
3. 3H] PY 108-068 J. Neural. Transm. 60:1984;169-197.
4. Czyrak A., Rogoz Z., Mogilnicka E., Maj J. The antianxiety effect of calcium channel antagonists and calcium agonist Bay K8644 in the four-plate test. Psychopharmacology (Berlin). 96:1988;S11.
5. Czyrak A., Mogilnicka E., Maj J. Dihydropyridine calcium channel antagonists as antidepressant drugs in mice and rats. Neuropharmacology. 28:1989;229-233.
6. Dubovsky S.L. Calcium antagonists. A new class of psychiatry drugs? Psychiatr. Ann. 16:1986;724-728.
7. File S.E., Baldwin H.A., Hitchcott P.K. Flumazenil but not nitrendipine reverses the increased anxiety during ethanol withdrawal in the rat. Psychopharmacology (Berlin). 98:1989;262-264.
8. File S.E., Zharkovsky A., Hitchcott P.K. Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal. Prog. Neuropsychopharmacol. Biol. Psychiatry. 16:1992;87-93.
9. Foehring R.C. Serotonin modulates N- and P-type calcium currents in neocortical pyramidal neurons via a membrane-delimited pathway. J. Neurophysiol. 75:1996;648-659.
10. Grebb J.A. Nifedipine and flunarizine block amphetamine-induced behavioral stimulation in mice. Life Sci. 38:1986;2375-2381.
11. Griebel G. 5-Hydroptamine-interacting drugs in animal models of anxiety disorders. More than 30 years of research Pharmacol. Ther. 65:1995;319-395.
12. 2+ channels. Mol. Pharmacol. 50:1996;1284-1294.
13. Hoffmeister F., Benz U., Heise A., Krause H.P., Neuser V. Behavioral effects of nimodipine in animals. Arzneittelforschung. 32:1982;347-360.
14. Kato T., Otsu Y., Furune Y., Yamamoto T. Different effects of L-, N- and T-type calcium channel blockers on striatal dopamine release measured by microdialysis in freely moving rats. Neurochem. Int. 21:1992;99-107.
15. Klein E., Uhde T.W. Controlled study of verapamil for treatment of panic disorder. Am. J. Psychiatry. 145:1988;431-434.
16. Martin M.I., Del val V.L., Colado M.I., Goicoechea C., Alfaro M.J. Behavioral and analgesic effects induced by administration of nifedipine and nimodipine. Pharmacol. Biochem. Behav. 55:1996;93-98.
17. 2+ channels antagonists with Vogel-type conflict test in rats. Eur. J. Pharmacol. 264:1994;107-110.
18. Middlemiss D.N., Spedding M. A functional correlate for the dihydropyrididne binding site in rat brain. Nature. 314:1985;94-96.
19. Miranda H.F., Paeile C. Interactions between analgesics and calcium channel blockers. Gen. Pharmacol. 21:1990;171-174.
20. Nordström R., Braesch-Andersen S., Bartfai T. Dopamine release is enhanced while acethylcholine release is inhibited by nimodipine (Bay e 9736). Acta Physiol. Scand. 126:1986;115-119.
21. 2+ current inhibition produced by serotonin in rat dorsal raphe neurons. J. Neurosci. 11:1991;3594-3609.
22. Penington N.J., Kelly J.S. Serotonin receptor activation reduces calcium current in an acutely dissociated adult central neuron. Neuron. 4:1990;751-758.
23. Pileblad E., Carlsson A. The Ca++-antagonist nimodipine decreases the Ca++-agonist Bay K 8644 increases catecholamine synthesis in mouse brain. Neuropharmacology. 26:1987;101-105.
24. Pucilowski O. Psychopharmacological properties of calcium channel inhibitors. Psychopharmacology (Berlin). 109:1992;12-29.
25. Pucilowski O., Eichelman B. Nicardipine protects against chronic-ethanol- or haloperidol-induced supersensitivity to apomorphine-induced agression. Neuropsychopharmacology. 5:1991;55-60.
26. Pucilowski O., Kostowski W. Increased anxiety during ethanol and diazepam withdrawal in rats. Effects of diltiazem and nicardipine Alcohol. Clin. Exp. Res. 15:1991;331.
27. Raeburn D., Gonzales R. CNS disorders and calcium antagonists. Trends Pharmacol. Sci. 9:1988;117-119.
28. 2+ channels in rat ventromedial hypothalamic neurons. Neuropharmacology. 35:1996;1093-1100.
29. Soubrié P. Neuropsychopharmacological profiles of calcium antagonists. Fundam. Clin. Pharmacol. 3:1989;71s-78s.
30. Tazi A., Farh M., Moumni M., Hakkou F. Potentiation of behaviour effects of a calcium channel antagonist, nifedipine, by ipsapirone. Behav. Pharmacol. 3:1992;269-273.
31. Viveros M.P., Martin S., Ormazabal M.J., Alfaro M.J., Martin M.I. Effects of nimodipine and nifedipine upon behavior and regional brain monoamines in the rat. Psychopharmacology (Berlin). 127:1996;123-132.
32. 2+ channels in supporting hippocampal synaptic transmission. Science. 264:1994;107-111.