Manipulation of NMDA-receptor activity alters extinction of an instrumental response in rats

Physiology and Behavior

Volumn 64, Issue 3, 1998, Pages 391-393

  Port, Richard L ^a   Seybold, Kevin S ^b  

^a SLIPPERY ROCK UNIVERSITY   (United States)

^b GROVE CITY COLLEGE   (United States)

Author keywords

Extinction; Long term potentiation (LTP); Memory; NMDA receptor

Indexed keywords

CYCLOSERINE; DIZOCILPINE MALEATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; LONG TERM POTENTIATION; MALE; MEMORY; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION;

EID: 0032100263     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(98)00095-X     Document Type: Article

References (30)

1. Berger T.W. Long-term potentiation of hippocampal synaptic transmission affects rate of behavioral learning. Science. 224:1984;627-630.
2. Berger T.W., Orr W.B. Hippocampectomy selectively disrupts discrimination reversal conditioning of the rabbit nictitating membrane response. Behav. Brain Res. 8:1983;49-68.
3. Bliss T.V.P., Garner-Medwin A.R. Long-lasting potentiation of synaptic transmission in the dentate area of the unanesthetized rabbit following stimulation of the perforant path. J. Physiol. 232:1973;357-374.
4. Cain D.P., Saucier D., Hall J., Hargreaves E.L., Boon F. Detailed behavioral analysis of water maze acquisition under APV or CNQX Contribution of sensorimotor disturbances to drug-induced acquisition deficits . Behav. Neurosci. 110:1996;86-102.
5. Clissold D.B., Ferkany J.W., Pontecorvo M.J. Competitive and noncompetitive NMDA antagonists, haloperidol and scopolamine impair performance in a nonspatial operant discrimination task. Psychobiol. 19:1991;332-338.
6. Cox J., Guthrie R., Macrae M., Kehoe E.J. MK801 impairs acquisition and expression of conditioned responses in the rabbit nictitating membrane preparation. Psychobiol. 22:1994;156-166.
7. Harris E.W., Ganong A.H., Cotman C.W. Long-term potentiation in the hippocampus involves activation of the N-methyl-D-aspartate receptors. Brain Res. 323:1984;132-137.
8. Holscher C. Long-term potentiation A good model for learning and memory? Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 21:1997;47-68.
9. Hood W.F., Compton R.P., Monahan J.B. D-cycloserine A ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristics . Neurosci. Lett. 98:1989;91-95.
10. Isaacson R.L., Douglas R.J., Moore R.Y. The effect of hippocampal ablation on acquisition of avoidance response. J. Comp. Physiol. Psychol. 54:1961;625-628.
11. Keith J.R., Rudy J.W. Why NMDA-receptor dependent long-term potentiation may not be a mechanism of learning and memory Reappraisal of the NMDA-receptor blockade strategy . Psychobiology. 18:1990;251-257.
12. Keller E.A., Borghese C.M., Carrer H.F., Ramirez O.A. The learning capacity of high or low performance rats is related to the hippocampus NMDA receptors. Brain Res. 576:1992;162-164.
13. Leung L.S., Brzosowski D., Shen B. Partial hippocampal kindling affects retention but not acquisition and place but not cue tasks on the radial arm maze. Behav. Neurosci. 110:1996;1017-1024.
14. 3H]TCP labelled receptors in rat brain. J. Neurosci. 8:1988;493-501.
15. Martinez J.L., Derrick B.E. Long-term potentiation and learning. Annu. Rev. Psychol. 47:1996;173-203.
16. Mathis C., Vogel E., Cagniard B., Criscuolo F., Ungerer A. The neurosteroid pregnenolone sulfate blocks deficits induced by a competitive NMDA antagonist in active avoidance and lever press learning in mice. Neuropharmacology. 35:1996;1057-1064.
17. Port R.L., Murphy H.A., Miller R.D., Seybold K.S. Hippocampal synaptic plasticity during instrumental learning. Current Psychol. 15:1997;332-339.
18. Rioux G.F., Robinson G.B. Hippocampal long-term potentiation does not affect either discrimination learning or reversal learning of the rabbit nictitating membrane response. Hippocampus. 5:1995;165-170.
19. Robinson G.B. Maintained saturation of hippocampal long-term potentiation does not disrupt acquisition in the eight-arm radial maze. Hippocampus. 2:1992;389-396.
20. Robinson G.B., Port R.L., Berger T.W. Kindling facilitates discriminative responding but disrupts reversal learning of the rabbit nictitating membrane response. Behav. Brain Res. 31:1989;279-283.
21. Ruske A.C., Harper D.N., Colombo M.W., White K.G. NMDA receptor action and spatial memory The effects of MK-801 and d-cycloserine on rate of forgetting and initial discriminability . Psychobiology. 23:1995;277-283.
22. Schmaltz L.W., Theios J. Acquisition and extinction of a classically conditioned response in hippocampectomized rabbits. J. Comp. Physiol. Psychol. 79:1972;328-333.
23. Schwartz B.L., Hashtroudi S., Herting R.L., Schwartz P., Deutsch S.I. D-Cycloserine enhances implicit memory in Alzheimer patients. Neurol. 46:1996;420-424.
24. Seybold K.S., Brown S.E., Lazzari M.W., Port R.L. Role of NMDA receptor activity in acquisition of an operant response. Neurosci. Abstr. 23:1997;2119.
25. Shapiro M.L., Caramanos Z. NMDA antagonist MK801 impairs acquisition but not performance of spatial working and reference memory. Psychobiology. 18:1990;231-243.
26. Sharp P.E., McNaughton B.L., Barnes C.A. Enhancement of hippocampal field potentials in rats exposed to a novel complex environment. Brain Res. 339:1985;361-365.
27. Skelton R.W., Scarth A.S., Wilkie D.M., Miller J.J., Phillips A.G. Long-term increases in dentate granule cell responsivity accompanies operant conditioning. J. Neurosci. 7:1987;3081-3087.
28. Steele R.J., Dermon C.R., Stewart M.G. D-cycloserine causes transient enhancement of memory for a weak aversive stimulus in day-old chicks. Neurobiol. Learn. Mem. 66:1996;236-240.
29. Weisz D.J., Clark G.A., Thompson R.F. Increased responsivity of dentate granule cells during nictitating membrane response conditioning in the rabbit. Behav. Brain Res. 12:1984;145-154.
30. Wong E.H.F., Kemp J.A., Priestley T., Knight A.R., Woodruff G.N., Iversen L.L. The anticonvulsant MK801 is a potent N-methyl-D-aspartate antagonist. Proc. Natl. Acad. Sci. USA. 83:1986;7104-7108.