Combinatorial libraries of transition-metal complexes, catalysts and materials

Current Opinion in Chemical Biology

Volumn 2, Issue 3, 1998, Pages 422-428

  Francis, Matthew B ^a   Jamison, Timothy F ^a   Jacobsen, Eric N ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; METAL; OLIGOPEPTIDE; PEPTIDE LIBRARY;

BINDING SITE; CATALYSIS; CHEMISTRY; DRUG DESIGN; METHODOLOGY; ORGANIC CHEMISTRY; REVIEW; SYNTHESIS;

BINDING SITES; CATALYSIS; CHEMISTRY, ORGANIC; DRUG DESIGN; LIGANDS; METALS; OLIGOPEPTIDES; PEPTIDE LIBRARY;

EID: 0032088271     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(98)80019-7     Document Type: Article

References (19)

1. 2+. J Org Chem 1995, 60:7382-7383.
2. Shibata N, Baldwin JE, Wood ME: Resin-bound peptide libraries showing specific metal ion binding. Bioorg Med Chem Lett 1997, 7:413-416.
3. Malin R, Steinbrecher R, Jannsen J, Semmler W, Noll B, Johannsen B, Frommel C, Höhne W, Schneider-Mergener J: Identification of technetium-99m binding peptides using combinatorial cellulose-bound peptide libraries. J Am Chem Soc 1995, 117:11821-11822.
4. Francis MB, Finney NS, Jacobsen EN: Combinatorial approach to the discovery of novel coordination complexes. J Am Chem Soc 1996, 118:8983-8984. By detecting metal binding with qualitative inorganic spot tests, selective binders of many transition metal ions can rapidly be identified from large libraries of novel ligands.
5. Menger FM, Eliseev AV, Migulin VA: Phosphatase catalysis developed via combinatorial organic chemistry. J Org Chem 1995, 60:6666-6667.
6. Burgess K, Lim HJ, Porte AM, Sulikowski GA: New catalysts and conditions for a C-H insertion reaction identified by high throughput catalyst screening. Angew Chem Int Ed 1996, 35:220-222.
7. Gilbertson SR, Chen G, McLoughlin M: Versatile building block for the synthesis of phosphine-containing peptides: The sulfide of diphenylphosphinoserine. J Am Chem Soc 1994, 116:4481-4482.
8. Gilbertson SR, Wang X: Synthesis of (dicyclohexylphosphino)serine, its incorporation into a dodecapeptide, and the coordination of rhodium. J Org Chem 1996, 61:434-435.
9. Gilbertson SR, Wang X: The combinatorial synthesis of chiral phosphine ligands. Tetrahedron Lett 1996, 37:6475-6478.
10. Cole BM, Shimizu KD, Krueger CA, Harrity JPA, Snapper ML, Hoveyda AH: Discovery of chiral catalysts through ligand diversity: Ti-catalyzed enantioselective addition of TMSCN to meso epoxides. Angew Chem Int Ed 1996, 35:1668-1671. Although combinatorial methods are not specifically employed in this study, the technique is readily adaptable to a combinatorial approach. Of greatest interest is the fact that a catalyst identified in this manner is the most enantioselective known for the investigated reaction.
11. Shimizu KD, Cole BM, Krueger CA, Kuntz KW, Snapper ML, Hoveyda AH: Search for chiral catalysts through ligand diversity: Substrate-specific catalysts and ligand screening on solid phase. Angew Chem Int Ed Engl 1997, 36:1704-1707.
12. Moates FC, Somani M, Annamalai J, Richardson JT, Luss D, Wilson RC: Infrared thermographic screening of combinatorial libraries of heterogeneous catalysts. Ind Eng Chem Res 1996, 35:4801-4803.
13. Hsieh-Wilson LC, Xiang XD, Schultz PG: Lessons from the immune system: From catalysis to materials science. Accounts Chem Res 1996, 29:164-170.
14. Xiang X-D, Schultz PG: The combinatorial synthesis and evaluation of functional materials. Physica C 1997, 282-287:428-430.
15. Xiang X-D, Sun X, Briceno G, Lou Y, Wang KA, Chang H, Wallace-Freedman WG, Chen SW, Schultz PG: A combinatorial approach to materials discovery. Science 1995, 268:1738-1740.
16. Briceno G, Chang H, Sun X, Schultz PG, Xiang X-D: A class of cobalt oxide magnetoresistance materials discovered with combinatorial synthesis. Science 1995, 270:273-275.
17. Sun X-D, Gao C, Wang J, Xiang X-D: Identification and optimization of advanced phosphors using combinatorial libraries. Appl Phys Lett 1997, 70:3353-3355.
18. Danielson E, Golden JH, McFarland EW, Reaves CM, Weiberg WH, Wu XD: A combinatorial approach to the discovery and optimization of luminescent materials. Nature 1997, 389:944-948. This paper features the preparation of a large combinatorial library and clever use of a charge-coupled device camera in a high-throughput quantitative assay. The figures and color photo illustrate both the synthesis method and the nature of the assay very clearly.
19. Baker BE, Kline NJ, Treado PJ, Natan MJ: Solution-based assembly of metal surfaces by combinatorial methods. J Am Chem Soc 1996, 118:8721-8722.