Clinical efficacy and tolerance of nabumetone in articular and non-articular rheumatic disorders: Personal experience during 12 weeks of treatment

Panminerva Medica

Volumn 40, Issue 2, 1998, Pages 110-115

  Coaccioli, S ^a   Allegra, A ^a   Di Cato, L ^a   Puxeddu, A ^a  

^a S MARIA HOSPITAL   (Italy)

Author keywords

Nabumetadone; Non steroidal anti inflammatory drugs; Osteoarthritis; Rheumatoid arthritis

Indexed keywords

ALKANONE; NABUMETONE; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MIDDLE AGED; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS;

ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, RHEUMATOID; BUTANONES; FEMALE; HUMANS; MALE; MIDDLE AGED; RHEUMATIC DISEASES;

EID: 0032088202     PISSN: 00310808     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Friedel HA, Todd PA. Nabumetone: a preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in rheumatic diseases. Drugs 1988;35:504-24.
2. Melarange R, Blower PR, Gentry C, O'Connell C. Nabumetone, an effective anti-inflammatory agent, lacks the gastric irritancy potential of piroxicam or ibuprofen. Br J Pharmacol 1990;99(Suppl):172 (abstract).
3. Hyneck ML. An overview of the clinical pharmacokinetics of nabumetone. J Rheumatol 1992;19(Suppl 36).20-4.
4. Boyle EA, Freeman PC, Mangan FR, Thomson MJ. Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new antiinflammatory agent. J Pharmacy Pharmacol 1982;34:562-9.
5. Brier ME, Aronoff GR. Multiple dose kinetics of nabumetone in renal impairment. Clin Res 1990;38:520a (abstract).
6. Vaiani G, Grossi E: Meta-analysis of Italian clinical trials of nabumetone. Drugs 1990;40 (Suppl 5):48-9.
7. Munzel P, Lemmel EE. Efficacy and safety of nabumetone in 4541 elderly patients from a drug monitoring study. Drug 1990;40(Suppl 5): 62-4.
8. Stroehmann I, Fedder M, Zeidler H. German drug monitoring studies with nabumetone. Drugs 1990;40(Suppl 5):38-42.
9. Stroehmann I, Giersch KH, Zeidler H, Munzel P. Efficacy and safety of nabumetone in patients with rheumatic diseases. Results of an outpatient study involving 8865 patients. Drugs 1990;40(Suppl 5):50-2.
10. Fleischmann RM. Clinical efficacy and safety of nabumetone in rheumatoid arthritis and osteoarthritis. J Rheumatol 1992,19(Suppl 36):32-40.
11. Emery P, Clarke A, Williams P, Kill D, Cree F, Rodhead R et al. Nabumetone compared with naproxen in the treatment of rheumatoid arthritis: a multicenter, double-blind, randomized, parallel group trial in hospital outpatients. J Rheumatol 1992;19(Suppl 36):41-7.
12. Coaccioli S, Allegra A, Puxeddu A, Nabumetone (N): clinical efficacy vs NSAIDs pool. An initial experience. Abstract. Meeting of the European League against Rheumatism. London (England). 1992. Br J Rheum 1992;31(Suppl 2):169.
13. Coaccioli S, Allegra A, Puxeddu A, Nabumetone (N): clinical efficacy vs NSAIDs pool. An initial experience. Abstract. Meeting of the European League against Rheumatism. London (England). 1992. Br J Rheum 1992;31(Suppl 2):169.
14. Friedel HA, Langtry HD, Buckley MM. Nabumetone. A re-appraisal of its pharmacology and therapeutic use in rehumatic diseases Drugs 1993;45(1):131-56.
15. Appelrouth DJ, Baim S, Chang RW, Cohen MH, England DW, Germain BF et al. Comparison of the safety and efficacy of nabumetone and aspirin in the treatment of osteoarthritis in adults. Am J Med 1987,83(Suppl 4B).78-81.
16. Pisko EJ, Bockow BI, Box P, Brodsky AL, Burch FX, Collins RL et al. Six-month mulucenter study comparing nabumetone and naproxen in the treatment of asteoarthritis. Am J Med 1987;83(Suppl. 4B):86-91.
17. Mullen BJ Results of a six-month study comparing the safety and efficacy of nahumetone and aspirin in the treatment of osteoarthritis. Am J Med 1987;83(Suppl 4B):74-77.
18. Rees T, Scott M, Saul S, Kill D, Fehilly B. A multicentre general practice trial of nabumetone and slow-release diclofenac in osteoarthritis. Drug Invest 1990;2:53-60.
19. Fedder M, Stroehmann I. Efficacy and safety of nabumetone in 5421 patients with osteoarthritis of the hip and/or knee joints: a subgroup evaluation of an outpatients study involving 18047 patients. Drug 1990;40(Suppl 5):75-7.
20. Abumi K, Kurakami C, Shirado O, Kyogoku H, Takahashi H. A clinical study of nabumetone on low back pain, neck-shoulder-arm syndrome and periarthritis scapulohumeralis. Shinyaku to Rinsho 1988;37:27-35
21. Tsuge K, Kato K, Taniguchi A, Hirayama A, Chigira M. Clinical study of nabumetone to lumbago, cervico-brachial syndrome and periarthritis scapulohumeralis. Rinsho Iyaku 1988;4:1465-75.
22. Muller-Fassbender HR. Open study of the efficacy and tolerability of nabumetone (Arthaxan) in extra-articular inflammation, (abstract), Meeting of the European League against Rheumatism. London, England, 1992. Br J Rheumatol 1992;31(Suppl 2):163.
23. Muller-Fassbender HR. Open study of the efficacy and tolerability of nabumetone (Arthaxan) in extra-articular inflammation, (abstract), Meeting of the European League against Rheumatism. London, England, 1992. Br J Rheumatol 1992;31(Suppl 2):163.
24. Haasters J. Nabumetone treatment of joint injuries caused by sporting activities. An open clinical trial of efficacy and tolerability. (asbtract), Meeting of the European League against Rheumatism. London, England, 1992. Br J Rheumatol 1992;31(Suppl 2):162.
25. Haasters J. Nabumetone treatment of joint injuries caused by sporting activities. An open clinical trial of efficacy and tolerability. (asbtract), Meeting of the European League against Rheumatism. London, England, 1992. Br J Rheumatol 1992;31(Suppl 2):162.
26. Jenner PN. Nabumetone in the treatment of skin and soft tissue injury. Am J Med 1987;83(Suppl 4B):101-6.
27. Arnett FC The 1987 revised ARA criteria for classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-9.
28. Yunus M. Primary fibromyalgia (fibrositis): clinical study of 50 patients with matched normal controls. Semin Arthritis Rheum 1981;11:151-62.
29. Inman WHW, Wilton LV, Pearce GL. Prescription-event monitoring of nabumetone. Pharmacol Med 1990;4:309-17.