A simple, inexpensive apparatus for performance of preparative scale solution phase multiple parallel synthesis of drug analogs. II. Biological evaluation of a retrospective library of quinolone antiinfective agents

Combinatorial Chemistry and High Throughput Screening

Volumn 1, Issue 2, 1998, Pages 89-99

  Frank, K E ^a   Devasthale, P V ^a   Gentry, E J ^a   Ravikumar, V T ^a   Keschavarz Shokri, A ^a   Mitscher, L A ^a   Nilius, A ^b   Shen, L L ^b   Shawar, R ^c   Baker, W R ^c  

^a UNIVERSITY OF KANSAS   (United States)

^b ABBOTT LABORATORIES   (United States)

^c PathoGenesis Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); ENZYME INHIBITOR; QUINOLONE DERIVATIVE; TEMAFLOXACIN;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; INSTRUMENTATION; METABOLISM; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; MYCOBACTERIUM; REFERENCE VALUE; SOLUTION AND SOLUBILITY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-INFECTIVE AGENTS; CHEMISTRY, PHARMACEUTICAL; DNA; DNA TOPOISOMERASES, TYPE II; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; FLUOROQUINOLONES; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM; QUINOLONES; REFERENCE VALUES; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032082971     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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