Expression of ε-IFN responsive genes in scavenger receptor over- expressing monocytes is associated with xanthomatosis

Atherosclerosis

Volumn 138, Issue 2, 1998, Pages 335-345

  Grewal, Thomas ^a,b   Boudreau, Mathieu ^a   Roy, Madeleine ^a   Chamberland, Ann ^a   Lefebvre, Chantal ^a   Lavigne, Jaques ^a   Davignon, Jean ^a   Minnich, Anne ^c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c SANOFI   (France)

Author keywords

Interferon; Foam cell; IP 10; Macrophage activation; Scavenger receptor; STAT ; Xanthoma

Indexed keywords

GAMMA INTERFERON INDUCIBLE PROTEIN 10; PROTEIN; RECOMBINANT GAMMA INTERFERON; SCAVENGER RECEPTOR; STAT1 PROTEIN; UNCLASSIFIED DRUG; ALPHA CHEMOKINE; CXC CHEMOKINE IP 10; CXC CHEMOKINE IP-10; GAMMA INTERFERON; GAMMA INTERFERON ACTIVATION FACTOR; IMMUNOGLOBULIN RECEPTOR; INTERFERON STIMULATED GENE FACTOR 3; LIPOPROTEIN RECEPTOR; MEMBRANE PROTEIN; MESSENGER RNA; SCARB1 PROTEIN, MOUSE; SCAVENGER RECEPTOR B; TRANSCRIPTION FACTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; FOAM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; MALE; MONOCYTE; PRIORITY JOURNAL; XANTHOMATOSIS; BIOSYNTHESIS; BLOOD; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED;

ADULT; AGED; CELLS, CULTURED; CHEMOKINES, CXC; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERFERON TYPE II; INTERFERON-STIMULATED GENE FACTOR 3; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MONOCYTES; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; RNA, MESSENGER; SCAVENGER RECEPTORS, CLASS B; TRANSCRIPTION FACTORS; XANTHOMATOSIS;

EID: 0032081249     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(98)00048-3     Document Type: Article

References (41)

1. Schaffner T, Taylor K, Bartucci K, Fischer-Dzoga K, Beeson J, Glasgow S, Wissler L Arterial foam cell with distinctive immuno-morphologic and histochemical features of macrophages. Am J Pathol. 100:1980;57-73.
2. Faggiotto A, Taylor K, Harker L., Studies of hypercholesterolemia in the non-human primate I Changes that lead to fatty streak formation. Arteriosclerosis. 4:1984;323-340.
3. Gerrity RG The role of the monocyte in atherogenesis. I. transition of blood borne monocytes into foam cells in fatty lesions. Am J Pathol. 103:1981;181-190.
4. Haberland ME, Fogelman AM The role of altered lipoproteins in the pathogenesis of atherosclerosis. Am Heart J. 113:1987;573-577.
5. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witzum JL Beyond cholesterol. Modifications of low density lipoproteins that increase its atherogenicity. New Engl J Med. 320:1989;915-924.
6. Brown MS, Goldstein JL Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu Rev Biochem. 52:1983;223-261.
7. Goldstein JL, Ho YK, Basu SK, Brown MS Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein producing massive cholesterol deposition. Proc Natl Acad Sci USA. 76:1979;333-337.
8. Shiratori Y, Okwu AK, Tabas I Free cholesterol loading of macrophages stimulates phosphatidylcholine biosynthesis and up-regulation of CTP-phosphocholine cytidyltransferase. J Biol Chem. 269:1994;1137-11348.
9. Kayden HJ, Maschio F, Traber MJ The secretion of apolipoprotein E by human monocyte-derived macrophages. Arch Biochem Biophys. 239:1985;388-395.
10. Bottalico LA, Keesler GA, Fless GM, Tabas I Cholesterol loading of macrophages leads to marked enhancement of native lipoprotein (a) and apolipoprotein (a) internalization and degradation. J Biol Chem. 268:1993;8569-8573.
11. Lesnik P, Rous M, Skarkatos S, Kruth HS, Chapman MJ Uptake of exogenous free cholesterol induces up-regulation of tissue factor expression in human monocyte-derived macrophages. Proc Natl Acad Sci USA. 89:1992;10370-10374.
12. Yla-Hertuala S, Lipton BA, Rosenfeld ME, Sarkoija T, Yoshimura T, Leonard EJ, Witztum JL, Steinberg D Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc Natl Acad Sci USA. 88:1991;5252-5256.
13. Wang N, Tabas I, Winchester R, Ravalli S, Rabbani LE, Tall A Interleukin-8 is induced by cholesterol loading of macrophages and expressed by macrophage foam cells in human atheroma. J Biol Chem. 271:1996;8837-8842.
14. Amento MP, Ehsani N, Palmer H, Libby P Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscler Thromb. 11:1991;1223-1230.
15. Ross R The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 362:1993;801-809.
16. Furue M, Suzuki H, Kodama T, Hiramoto T, Sugiyama H, Tamaki K Colocalization of scavenger receptor in CD68 positive foam cells in verruciform xanthoma. J Dermatol Sci. 10:1995;213-219.
17. Giry C, Giroux LM, Roy M, Davignon J, Minnich A Characterization of inherited scavenger receptor over-expression and abnormal macrophage phenotype in a normolipidemic subject with planar xanthoma. J Lipid Res. 37:1996;1422-1435.
18. Liang P, Pardee AB. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction, Science 1992;257:967-971.
19. Liang P, Averboukh L, Pardee AB Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization. Nucleic Acids Res. 14:1993;3269-3275.
20. Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84 kDa ISGF-3 proteins that are activated by IFN-α Proc Natl Acad Sci USA. 89:1992;7836-7839.
21. Ohmori Y, Hamilton TR The IFN-stimulated response element and a κ B site mediate synergistic induction of murine IP-10 gene transcription by IFN-γ and TNF-α J Immunol. 154:1995;5235-5244.
22. Fogelman AM, Elahi F, Sykes K, Van Lenten BJ, Territo MC, Berliner JA Modification of the Recalde method for the isolation of human monocytes. J Lipid Res. 29:1988;1243-1247.
23. Lindgren FT. In: Perkins EG, editors. Analysis of Lipids and Lipoproteins. Champaign, IL: American Oil Chemists Society, 1975:204-224.
24. Basu SK, Goldstein JL, Anderson GW, Brown MS Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts. Proc Natl Acad Sci USA. 73:1976;3178-3182.
25. Noble RP Electrophoretic separation of plasma lipoprotein species by paper electrophoresis in albumin-containing buffer. J Lipid Res. 9:1968;693-700.
26. Markwell MK, Haas SM, Tolbert NE A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem. 87:1978;206-210.
27. Innerarity TL, Pitas RE, Mahley RW. In: Albers JJ, Segrest JP, editors. Methods in Enzymology 129: Lipoprotein-Receptor Interactions. Academic Press, New York, 1986;542-565.
28. Chomczynski P, Sacchi N Single-step method of RNA isolation by acid guanidinium-thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:1987;156-159.
29. Tso JY, Sun XH, Kao T, Reece KS, Wu R Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res. 13:1985;2485-2502.
30. Luster AD, Ravetch JV Genomic characterization of a γ-IFN-inducible gene (IP-10) and identification of an IFN-inducible hypersensitive site. Mol Cell Biol. 10:1987;3723-3731.
31. Muller MM, Schreiber E, Schaffner W, Matthias P Rapid test for in vivo stability and DNA binding of mutated octamer binding proteins with 'mini-extracts' prepared from transfected cells. Nucleic Acids Res. 17:1989;6420.
32. Eilers A, Seegert D, Schindler C, Baccarini M, Decker T The response of γ IFN Activation Factor is under developmental control in cells of the macrophage lineage. Mol Cell Biol. 6:1993;3245-3254.
33. Chiu R, Angel P, Karin M JunB differs in its biological properties from, and is a negative regulator of c-jun. Cell. 59:1989;979-986.
34. Schindler C, Darnell JE Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem. 64:1995;621-651.
35. Young HA, Hardy KJ Role of interferon-γ in immune cell regulation. J Leuk Biol. 5:1995;373-381.
36. Luster AD, Unkeless JC, Ravetch JV IFN transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature. 315:1985;672-676.
37. Wang X, Yue TL, Ohlstein EH, Sung CP, Feuerstein GZ IFN-inducible protein-10 involves vascular smooth muscle cell migration, proliferation and inflammatory response. J Biol Chem. 271:1996;24286-24293.
38. Enk AH, Katz SI Early molecular events in the induction phase of contact sensitivity. Proc Natl Acad Sci USA. 89:1992;1398-1402.
39. Kaplan G, Luster AD, Hancock G, Cohn ZA The expression of a γ-interferon-induced protein (IP-10) in delayed-type immune responses in human skin. J Exp Med. 166:1987;1098-1108.
40. Taub DD, Lloyd AR, Conlon K, Wang JM, Ortaldo JR, Harada A, Matsushima K, Kelvin DJ, Oppenheim JJ Recombinant Human IFN-inducible Protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med. 177:1993;1809-1814.
41. Gupta S, Pablo AM, Jiang XC, Wang N, Tall AR, Schindler C IFN-γ potentiates atherosclerosis in apoE knock-out mice. J Clin Invest. 11:1997;2752-2761.