Virulence of catalase-deficient Aspergillus nidulans in p47(phox-/-) mice: Implications for fungal pathogenicity and host defense in chronic granulomatous disease

Journal of Clinical Investigation

Volumn 101, Issue 9, 1998, Pages 1843-1850

  Chang, Y C ^a   Segal, B H ^b   Holland, S M ^b   Miller, G F ^c   Kwon Chung, K J ^a,b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

catA; Catalase; catB; CGD; P47(phox)

Indexed keywords

CATALASE;

ANIMAL EXPERIMENT; ARTICLE; ASPERGILLUS NIDULANS; CHRONIC GRANULOMATOUS DISEASE; HOST RESISTANCE; INFECTION RISK; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRULENCE;

EID: 0032080869     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2301     Document Type: Article

References (36)

1. Gallin, J.I., E.S. Buescher, B.E. Seligmann, J. Nath, T. Gaither, and P. Katz. 1983. NIH conference. Recent advances in chronic granulomatous disease. Ann. Intern. Med. 99:657-674.
2. Mouy, R., F. Veber, S. Blanche, J. Donadieu, R. Brauner, J.C. Levron, C. Griscelli, and A. Fischer. 1994. Long-term itraconazole prophylaxis against Aspergillus infections in thirty-two patients with chronic granulomatous disease. J. Pediatr. 125:998-1003.
3. Pasic, S., M. Abinun, B. Pistignjat, B. Vlajic, J. Rakic, L. Sarjanovic, and N. Ostojic. 1996. Aspergillus osteomyelitis in chronic granulomatous disease: treatment with recombinant gamma-interferon and itraconazole. Pediatr. Infect. Dis. J. 15:833-834.
4. Casson, D.H., F.A. Riordan, and E.J. Ladusens. 1996. Aspergillus endocarditis in chronic granulomatous disease. Acta. Paediatr. 85:758-759.
5. Liese, J.G., V. Jendrossek, A. Jansson, T. Petropoulou, S. Kloos, M. Gahr, and B.H. Belohradsky. 1996. Chronic granulomatous disease in adults [see comments]. Lancet. 347:220-223.
6. Holmes, B., and R.A. Good. 1972. Laboratory models of chronic granulomatous disease. J. Reticuloendothel. Soc. 12:216-237.
7. Pitt, J., and H.P. Bernheimer. 1974. Role of peroxide in phagocytic killing of pneumococci. Infect. Immun. 9:48-52.
8. Diamond, R.D., and R.A. Clark. 1982. Damage to Aspergillus fumigatus and Rhizopus oryzae hyphae by oxidative and nonoxidative microbicidal products of human neutrophils in vitro. Infect. Immun. 38:487-495.
9. Diamond, R.D., R. Krzesicki, B. Epstein, and W. Jao. 1978. Damage to hyphal forms of fungi by human leukocytes in vitro. A possible host defense mechanism in aspergillosis and mucormycosis. Am. J. Pathol. 91:313-328.
10. Pollock, J.D., D.A. Williams, M.A.C. Gifford, L.L. Li, X. Du, J. Fisherman, S.H. Orkin, C.M. Doerschuk, and M.C. Dinauer. 1995. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nat. Genet. 9:202-209.
11. Morgenstern, D.E., M.A. Gifford, L.L. Li, C.M. Doerschuk, and M.C. Dinauer. 1997. Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus. J. Exp. Med. 185:207-218.
12. Bjorgvinsdottir, H., C. Ding, N. Pech, M.A. Gifford, L.L. Li, and M.C. Dinauer. 1997. Retroviral-mediated gene transfer of gp91phox into bone marrow cells rescues defect in host defense against Aspergillus fumigatus in murine X-linked chronic granulomatous disease. Blood. 89:41-48.
13. White, C.J., C.K. Kwon, and J.I. Gallin. 1988. Chronic granulomatous disease of childhood. An unusual case of infection with Aspergillus nidulans var. echinulatus. Am. J. Clin. Pathol. 90:312-316.
14. Cohen, M.S., R.E. Isturiz, H.L. Malech, R.K. Root, C.M. Wilfert, L. Gutman, and R.H. Buckley. 1981. Fungal infection in chronic granulomatous disease. The importance of the phagocyte in defense against fungi. Am. J. Med. 71:59-66.
15. Timherlake, W.E. 1987. Molecular genetic analysis of development in Aspergillus nidulans. In Genetic Regulation of Development. W.R. Loomis, editor. Alan R. Liss, New York. 343-357.
16. Clutterbuck, A.J. 1974. Aspergillus nidulans. In Aspergillus nidulans. Vol. 1. R.C. King, editor. Plenum Press, New York. 447-510.
17. Pontecorvo, G., J.A. Poper, L.M. Hemmans, K.D. McDonald, and A.W.J. Bufton. 1953. The genetics of Aspergillus nidulans. Adv. Genet. 5:141-238.
18. Navarro, R.E., M.A. Stringer, W. Hansberg, W.E. Timberlake, and J. Aguirre. 1996. catA, a new Aspergillus nidulans gene encoding a developmentally regulated catalase. Curr. Genet. 29:352-359.
19. Kawasaki, L., D. Wysong, R. Diamond, and J. Aguirre. 1997. Two divergent catalase genes are differentially regulated during Aspergillus nidulans development and oxidative stress. J. Bacteriol. 179:3284-3292.
20. phox mouse knock-out model of chronic granulomatous disease. J. Exp. Med. 182:751-758.
21. Kaefer, E. 1977. Meiotic and mitotic recombination in Aspergillus and its chromosomal aberrations. Adv. Genet. 19:33-131.
22. Yelton, M.M., J.E. Hamer, and W.E. Timberlake. 1984. Transformation of Aspergillus nidulans by using a trpC plasmid. Proc. Natl. Acad. Sci. USA. 81: 1470-1474.
23. Bradford, M.M. 1976. A rapid and sensitive method for the quantilation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
24. Chary, P., and D.O. Natvig. 1989. Evidence for three differentially regulated catalase genes in Neurospora crassa: effects of oxidative stress, heat shock, and development. J. Bacteriol. 171:2646-2652.
25. Harris, H. 1976. Handbook of Enzyme Electrophoresis in Human Genetics. North-Holland Publishing Co., Amsterdam.
26. Timberlake, W.E. 1980. Developmental gene regulation in Aspergillus nidulans. Dev. Biol. 78:497-510.
27. Feinberg, A.P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13.
28. Meshulam, T., S.M. Levitz, L. Christin, and R.D. Diamond. 1995. A simplified new assay for assessment of fungal cell damage with the tetrazolium dye, (2,3)-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT). J. Infect. Dis. 172:1153-1156.
29. Levitz, S.M., and R.D. Diamond. 1985. A rapid colorimetric assay of fungal viability with the tetrazolium salt MTT. J. Infect. Dis. 152:938-945.
30. Rex, J.H., J.E. Bennett, J.I. Gallin, H.L. Malech, and D.A. Melnick. 1990. Normal and deficient neutrophils can cooperate to damage Aspergillus fumigatus hyphae. J. Infect. Dis. 162:523-528.
31. Roilides, E., K. Uhlig, D. Venzon, P.A. Pizzo, and T.J. Walsh. 1993. Enhancement of oxidative response and damage caused by human neutrophils to Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon. Infect. Immun. 61:1185-1193.
32. Hearn, V.M., E.V. Wilson, and D.W. Mackenzie. 1992. Analysis of Aspergillus fumigatus catalases possessing antigenic activity. J. Med. Microbiol. 36: 61-67.
33. Calera, J.A., S. Paris, M. Monod, A.J. Hamilton, J.P. Debeaupuis, M. Diaquin, R. Lopez-Medrano, F. Leal, and J.P. Latge. 1997. Cloning and disruption of the antigenic catalase gene of Aspergillus fumigatus. Infect. Immun. 65: 4718-4724.
34. Brown, S.M., M.L. Howell, M.L. Vasil, A.J. Anderson, and D.J. Hassett. 1995. Cloning and characterization of the katB gene of Pseudomonas aeruginosa encoding a hydrogen peroxide-inducible catalase: purification of KatB, cellular localization, and demonstration that it is essential for optimal resistance to hydrogen peroxide. J. Bacteriol. 177:6536-6544.
35. Hassett, D.J., and M.S. Cohen. 1989. Bacterial adaptation to oxidative stress: implications for pathogenesis and interaction with phagocyte cells. FASEB (Fed. Am. Soc. Exp. Biol.) J. 3:2574-2582.
36. Imlay, J.A., and S. Linn. 1987. Mutagenesis and stress responses induced in Escherichia coli by hydrogen peroxide. J. Bacteriol. 169:2967-2976.