BRCA-associated breast cancer: Absence of a characteristic immunophenotype

Cancer Research

Volumn 58, Issue 9, 1998, Pages 1839-1842

  Robson, Marc ^a   Rajan, Prabha ^a   Rosen, Paul Peter ^a   Gilewski, Theresa ^a   Hirschaut, Yashar ^a   Pressman, Peter ^a   Haas, Bruce ^a   Norton, Larry ^a   Offit, Kenneth ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CATHEPSIN D; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; HORMONE RECEPTOR; PROTEIN P27; PROTEIN P53;

ADULT; ARTICLE; BREAST CARCINOMA; CANCER CLASSIFICATION; CANCER STAGING; CANCER SURVIVAL; CLINICAL FEATURE; DISEASE ASSOCIATION; ETHNOLOGY; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; JEW; MAJOR CLINICAL STUDY; MITOSIS RATE; ONCOGENE; ONSET AGE; OUTCOMES RESEARCH; PRIORITY JOURNAL; TUMOR VOLUME;

ADULT; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, DUCTAL, BREAST; CARCINOMA, LOBULAR; COHORT STUDIES; FEMALE; GENE FREQUENCY; GENES, BRCA1; GERM-LINE MUTATION; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; NEOPLASM PROTEINS; TRANSCRIPTION FACTORS;

EID: 0032080659     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Parker, S. L., Tong, T., Bolden, S., and Wingo, P. A. Cancer statistics, 1997. CA Cancer J. Clin., 47: 5-27, 1997.
2. Claus, E. B., Schildkraut, J. M., Thompson, W. D., and Risch, N. J. The genetic attributable risk of breast and ovarian cancer. Cancer (Phila.), 77: 2318-2324, 1996.
3. Ford, D., Easton, D. F., Bishop, D. T., Narod, S. A., Goldgar, D. E., and Consortium, B. C. L. Risks of cancer in BRCA1-mutation carriers. Lancet, 343: 692-695, 1994.
4. Easton, D. F., Ford, D., Bishop, D. T., and Breast Cancer Linkage Consortium. Breast and ovarian cancer incidence in BRCA1-mutation carriers. Am. J. Hum. Genet., 56: 265-271, 1995.
5. Struewing, J. P., Hartge, P., Wacholder, S., Baker, S. M., Berlin, M., McAdams, M., Timmerman, M. M., Brody, L. C., and Tucker, M. A. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N. Engl. J. Med., 336: 1401-1408, 1997.
6. Jacquemier, J., Eisinger, F., Birnbaum, D., and Sobol, H. Histoprognostic grade in BRCA1-associated breast cancer. Lancet, 345: 1503, 1995.
7. Bignon, Y-J., Fonck, Y., and Chassagne, M. C. Histoprognostic grade in tumours from families with hereditary predisposition to breast cancer. Lancet, 346: 258, 1995.
8. Eisinger, F., Stoppa-Lyonnet, D., Longy, M., Kerangueven, F., Noguchi, T., Bailly, C., Vincent-Salomon, A., Jacquemier, J., Birnbaum, D., and Sobol, H. Germ-line mutation at BRCA1 affects the histoprognostic grade in hereditary breast cancer. Cancer Res., 56: 471-474, 1996.
9. Marcus, J. N., Watson, P., Page, D. L., Narod, S. A., Lenoir, G. M., Tonin, P., Linder-Stephenson, L., Salerno, G., Conway, T. A., and Lynch, H. T. Hereditary breast cancer: pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage. Cancer (Phila.), 77: 697-709, 1996.
10. Johannsson, O. T., Idvall, I., Anderson, C., Borg, A., Barkadottir, R. B., Egilsson, V., and Olsson, H. Tumour biological features of BRCA1-induced breast and ovarian cancer. Eur. J. Cancer, 33: 362-371, 1997.
11. Breast Cancer Linkage Consortium. Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Lancet, 349: 1505-1510, 1997.
12. Offit, K., Gilewski, T., McGuire, P., Schluger, A., Hampel, H., Brown, K., Swensen, J., Neuhausen, S., Skolnick, M., Norton, L., and Goldgar, D. Germline BRCA1 185delAG mutations in Jewish women with breast cancer. Lancet, 347: 1643-1647, 1996.
13. Neuhausen, S., Gilewski, T., Norton, L., Tran, T., McGuire, P., Swensen, J., Hampel, H., Borgen, P., Brown, K., Skolnick, M., Shattuck-Eidens, D., Jhanwar, S., Goldgar, D., and Offit, K. Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer. Nat. Genet., 13: 126-128, 1996.
14. Oddoux, C., Struewing, J. P., Clayton, C. M., Neuhausen, S., Brody, L. C., Kaback, M., Haas, B., Norton, L., Borgen, P., Jhanwar, S., Goldgar, D., Ostrer, H., and Offit, K. The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%. Nat. Genet., 14: 188-190, 1996.
15. Tonin, P., Weber, B., Offit, K., Couch, F., Rebbeck, T. R., Neuhausen, S., Godwin, A. K., Daly, M., Wagner-Costalos, J., Berman, D., Grana, G., Fox, E., Kane, M. F., Kolodner, R. D., Krainer, M., Haber, D. A., Streuwing, J. P., Warner, E., Rosen, B., Lerman, C., Peshkin, B., Norton, L., Serova, O., Foulkes, W. D., Lynch, H. T., Lenoir, G. M., Narod, S. A., and Garber, J. E. Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nat. Med., 2: 1179-1183, 1996.
16. Struewing, J. P., Abeliovich, D., Peretz, T., Avishai, N., Kaback, M. M., Collins, F. S., and Brody, L. C. The carrier frequency of the BRCA1 185delAG mutation is approximately 1% in Ashkenazi Jewish individuals. Nat. Genet., 11: 198-200, 1995.
17. Roa, B. B., Boyd, A. A., Volcik, K., and Richards, C. S. Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2. Nat. Genet., 14: 185-187, 1996.
18. Bloom, H. J. G., and Richardson, W. W. Histological grading and prognosis in breast cancer. Br. J. Cancer, 11: 359-377, 1937.
19. Cutler, S. J., Black, M. M., Mosk, T., Harvei, S., and Freeman, C. Further observations on prognostic factors in cancer of the female breast. Cancer (Phila.), 24: 653-667, 1969.
20. Black, M. M., Barclay, T. H. C., and Hankey, B. F. Prognosis in breast cancer utilizing histologic characteristics of the primary tumor. Cancer (Phila.), 36: 2048-2055, 1975.
21. Albain, K. S., Allred, D. C., and Clark, G. M. Breast cancer outcome and predictors of outcome: are there age differentials? J. Natl. Cancer Inst. Monogr., 16: 35-42, 1994.
22. Fisher, C. J., Egan, M. K., Smith, P., Wicks, K., Millis, R. R., and Fentiman, I. S. Histopathology of breast cancer in relation to age. Br. J. Cancer, 75: 593-596, 1997.
23. Nixon, A. J., Neuberg, D., Hayes, D. F., Gelman, R., Connolly, J. L., Schnitt, S., Abner, A., Recht, A., Vicini, F., and Harris, J. R. Relationship of patient age to pathologic features of the tumor and prognosis for patients with stage I or II breast cancer. J. Clin. Oncol., 12: 888-894, 1994.
24. Holli, K., and Isola, J. Effect of age on the survival of breast cancer patients. Eur. J. Cancer, 33: 425-428, 1997.
25. Smith, S. A., Easton, D. F., Evans, D. G. R., and Ponder, B. A. J. Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome. Nat. Genet., 2: 128-131, 1992.
26. Cornelis, R. S., Neuhausen, S. L., Johannsson, O., Arason, A., Kelsell, D., Ponder, B. A. J., Tonin, P., Hamann, U., Lindblom, A., Lalle, P., Longy, M., Olah, E., Scherneck, S., Bignon, Y-J., Sobol, H., Chang-Claude, J., Larsson, C., Spurr, N., Borg, A., Barkardottir, R. B., Narod, S., and Devilee, P. High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCA1-linked families. Genes Chromosomes Cancer, 13: 203-210, 1995.
27. Thompson, M. E., Jensen, R. A., Obermiller, P. S., Page, D. L., and Holt, J. T. Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nat. Genet., 9: 444-450, 1995.
28. Holt, J. T., Thompson, M. E., Szabo, C., Robinson-Benion, C., Artega, C. L., King, M-C., and Jensen, R. A. Growth retardation and tumor inhibition by BRCA1. Nat. Genet., 12: 298-302, 1996.