Mechanism of 17α-Hydroxylase/17,20-Lyase - An initial geometric perspective for the lyase of the C(17)-C(20) bond of C21 steroids

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 9, 1998, Pages 1023-1028

  Ahmed, Sabbir ^a   Owen, Caroline P ^a  

^a KINGSTON UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

STEROID 17,20 LYASE; STEROID 17ALPHA MONOOXYGENASE;

ARTICLE; BINDING SITE; COMPLEX FORMATION; DRUG MECHANISM; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; PROSTATE CANCER;

17-ALPHA-HYDROXYPREGNENOLONE; AROMATASE; BINDING SITES; HEME; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PEROXIDES; STEROID 17-ALPHA-HYDROXYLASE; SUBSTRATE SPECIFICITY;

EID: 0032080361     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00154-1     Document Type: Article

References (9)

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