Large-scale preparation of human thrombin: Polyethylene glycol potentiates the factor Xa-mediated activation of prothrombin

Thrombosis Research

Volumn 90, Issue 3, 1998, Pages 101-109

  Kaetsu, Hiroshi ^a   Mizuguchi, Jun ^a   Hamamoto, Takayoshi ^a   Kamimura, Koichiro ^a   Yoshida, Yasuko ^a   Nakagaki, Tomohiro ^a   Ogata, Yoichi ^a   Miyamoto, Seiji ^a   Funatsu, Akinobu ^a  

^a Kaketsuken   (Japan)

Author keywords

Activation; Factor X; Osmotic stress; Polyethylene glycol; Prothrombin; Thrombin

Indexed keywords

BLOOD CLOTTING FACTOR 10A; CALCIUM CHLORIDE; MACROGOL 400; PROTHROMBIN; THROMBIN;

ARTICLE; BLOOD CLOTTING; DRUG MANUFACTURE; DRUG MIXTURE; DRUG POTENTIATION; DRUG SYNTHESIS; MOLECULAR WEIGHT; OSMOTIC STRESS; PRIORITY JOURNAL;

CALCIUM CHLORIDE; DRUG INDUSTRY; ENZYME ACTIVATION; FACTOR XA; GLYCEROL; HUMANS; MANUFACTURED MATERIALS; MOLECULAR WEIGHT; OSMOLAR CONCENTRATION; POLYETHYLENE GLYCOLS; PROTHROMBIN; TEMPERATURE; THROMBIN; TIME FACTORS;

EID: 0032079535     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(98)00026-7     Document Type: Article

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