The impermeant ion methylammonium blocks K+ and NH4+ currents through KAT1 channel differently: Evidence for ion interaction in channel permeation

Journal of Membrane Biology

Volumn 163, Issue 1, 1998, Pages 25-35

  Moroni, A ^a   Bardella, L ^b   Thiel, G ^c  

^a Dipartimento di Biologia   (Italy)

^b Istituto di Patologia Generale   (Italy)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Ammonium (NH4+); Block; KAT1; Methylammonium (MA); Permeation; Potassium channel

Indexed keywords

AMMONIA; METHYLAMMONIUM; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; ION CURRENT; ION TRANSPORT; NONHUMAN; OOCYTE; PLANT CELL; POTASSIUM CURRENT; PROTEIN EXPRESSION;

AMMONIUM CHLORIDE; ANIMALS; CELL MEMBRANE PERMEABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; IONS; METHYLAMINES; PLANT PROTEINS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; POTASSIUM CHLORIDE; XENOPUS;

ANIMALIA;

EID: 0032079390     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900367     Document Type: Article

References (30)

1. Andersen, J.A., Huprikar, S.S., Kochian, L.V., Lucas, W.J., Gaber, R.F. 1992. Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 89:3736-3740
2. Armstrong, CM. 1971. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons. J. Gen. Physiol. 58:413-437
3. + channel KAT1. Proc. Natl. Sci. USA 93:8123-8128
4. + channels of stromatal guard cells: characteristics of the inward rectifier and its control by pH. J. Gen. Physiol. 99:615-644
5. + channel of stromatal guard cells: Abscisic-acid-evoked control of the outward rectifier mediated by cytoplasmic pH. Planta 191: 330-341
6. Burckhardt, B.C., Thelen, P. 1995. Effect of primary, secondary and tertiary amines on membrane potential and intracellular pH in Xenopus laevis oocytes. Pfluegers Arch. 429:306-312
7. Cao, Y., Ward, J.M., Kelly, W.B., Ichida, A.M., Gaber, R.F., Anderson, J.A., Uozumi, N., Schroeder, J.I., Crawford, N.M. 1995. Multiple genes, tissue specificity and expression-dependent modulation contribute to the functional diversity of potassium channels in Arabidopsis thaliana. Plant Physiol. 109:1093-1106
8. DiFrancesco, D. 1982. Block and activation of the pace-maker channel in calf Purkinje fibres: effects of potassium, caesium and rubidium. J. Physiol. 329:485-507
9. French, R.J., Shoukimas, J.J. 1985. An ion's view of the potassium channel. J. Gen. Physiol. 85:669-698
10. Greenway H., Munns, R. 1980. Mechanism of salt tolerance in nonhalophytes. Annu. Rev. Plant Physiol. 31:149-190
11. + mixtures. J. Gen. Physiol. 70:269-281
12. Hille, B. 1975. Ion selectivity of Na and K channels of nerve membrane. In: Membranes: A Series of Advances, G. Eisenman, editor, vol 3. pp. 255-323, Marcel Dekker, New York
13. Hille, B. 1992. Ionic channels of excitable membranes. Second edition. Sinauer Associates. Sunderland. Massachusetts
14. Hoshi, T. 1995. Regulation of voltage dependence of the KAT1 channel by intracellular factors. J. Gen. Physiol. 105:309-320
15. + Channel KAT1. J. Membrane Biol. 151:53-62
16. + channel functions. Annu. Rev. Physiol. 54:537-555
17. Kubo, Y., Baldwin, J., Jan, Y.N., Jan, L.Y. 1993. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature 362:127-133
18. + channel pore. J. Biol. Chem. 272:1011-1018
19. Pongs, O. 1992. Molecular biology of voltage-dependent potassium channels. Physiol. Rev. 72:S69-S88
20. Schachtman, D.P., Schroeder, J.I., Lucas, W.J., Anderson, J.A., Gaber, R.F. 1992. Expression of an Inward-rectifying potassium Channel by the Arabidopsis KAT1 cDNA. Science 258:1654-1657
21. + uptake. Annu. Rev. Biophys. Biomol. Struct. 23:442-471
22. Segel, E. 1975. Enzyme Kinetics, pp. 170-173. Wiley and Sons. New York
23. Shenhan, J.J., Ribeiro-Neto, L., Sussman, M.R. 1993. Cesium insensitive mutants of Arabidopsis thaliana. Plant J. 3:647-656
24. Uozumi, N., Gassman, W., Cao, Y., Schroeder, J.I. 1995. Identification of strong modifications in cation selectivity in Arabidopsis thaliana inward rectifying potassium channel by mutant selection in yeast. J. of Biol. Chem. 270:24276-24281
25. + pump activity. Bot. Acta 110:369-377
26. + channel. Pfluegers Arch. 428:422-424
27. + channel in Xenopus oocytes: analysis of macroscopic currents. The Plant Journal 7:321-332
28. + channel in the plasma membrane of rye roots. J. Membrane Biol. 152:89-96
29. Woodhull, A. 1973. Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61:687-708
30. Wu, J.V. 1992. Dynamic ion-ion and water-ion interactions in ion channels. Biophys. J. 61:1316-1331.