The neurotrophins and neuropoietic cytokines: Two families of growth factors acting on neural and hematopoietic cells

Annals of the New York Academy of Sciences

Volumn 840, Issue , 1998, Pages 97-106

  Nancy, Y I P ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CYTOKINE; GROWTH FACTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN; PROTEIN TYROSINE KINASE; RECEPTOR;

CANCER CELL CULTURE; CELL DIFFERENTIATION; CONFERENCE PAPER; EMBRYONAL CARCINOMA; HEMATOPOIETIC CELL; LEUKEMIA CELL LINE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PRECURSOR; SIGNAL TRANSDUCTION; STEM CELL;

EID: 0032077516     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb09553.x     Document Type: Conference Paper

References (46)

1. IP, N. Y. & G. D. YANCOPOULOS. 1994. Neurotrophic factor receptors: Just like other growth factor and cytokine receptors? Curr. Opin. Neurobiol. 4: 400-405.
2. IP, N. Y. & G. D. YANCOPOULOS. 1996. The neurotrophins and CNTF: Two families of collaborative neurotrophic factors. Ann. Rev. Neurosci. 19:491-515.
3. IP, N. Y, T. G. BOULTON, Y. Li, J. M. VERDI, S. J. BIRREN, D. J. ANDERSON & G. D. YAKCOPOULOS. 1994. CNTF, FGF and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons. Neuron 13:443-455.
4. BOTHWELL, M. 1995. Functional interactions of neurotrophins and neurotrophin receptors. Ann. Rev. Neurosci. 18:223-253.
5. IP, N. Y, T. N. STITT, P. TAPLEY, R. KLEIN, D. J. GLASS, J. FANDL, L. A. GREENE, M. BARDACID &G. D. YANCOPOULOS. 1993. Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells. Neuron 10:137-149.
6. SNIDER, W. D. 1994. Functions of the neurotrophins during nervous system development: What the knockouts are teaching us. Cell 77:627-638.
7. LINDSAY, R. M. 1994. Neurotrophins and receptors. Prog. Brain Res. 103:3-14.
8. IP, N. Y, Y. LI, G. D. YANCOPOULOS & R. M. LLNIDSAY. 1993. Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF. J. Neurosci. 13: 3394-3405.
9. COXOVER, J. C, J. T. ERICKSON, D. M. KATZ, L. M. BIANCHI, W. T. POUEYMIROU, J. MCCLAIN, L. PAN, M. HELGREN, N. Y. IP, P. BOLAND, B. FRIEDMAN, S. WEIGAND, R. VEJSADA, A. C. KATO, T. M. DECHIARA & G. D. YANCOPOULOS. 1995. Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4. Nature 375:235-238.
10. CROWLEY, C., S. D. SPENCER, M. C. NISHLMURA, K. S. CIIEN, S. PITTS-MEEK, M. P. ARMANINI, L. H. LING, S. B. MCMAHON, D. L. SHELTON, A. D. LEVINSON & H. S. PHILLIPS. 1994. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76: 1001-1011.
11. CHEVALIER, S., V. PRALORAN, C. SMITH, D. M. GROGAN, N. Y. IP, G. D. YANCOPOULOS, P. BRACHET, A. POUPLARD & H. GASCAN. 1994. Expression and functionality of the trkA proto-oncogene product/NGF receptor in undifferentiated hematopoietic cells. Blood 83:1479-1485.
12. LOMEN-HOERTH, C. & E. M. SHOOTER. 1995. Widespread neurotrophin receptor expression in the immune system and other nonneuronal rat tissues. J. Neurochem. 64: 1780-1789.
13. MATSUDA, H., M. D. COUGHLLM, J. BIENENSTOCK & J. A. DENBURG. 1988. Nerve growth factor promotes human hemopoietic colony growth and differentiation. Proc. Natl. Acad. Sci. USA 85:6508-6512.
14. TSUDA, T., D. WoNG, J. DOLOVICH, J. BIENENSTOCK, J. MARSHALL & J. A. DENBURG. 1991. Synergistic effects of nerve growth factor and granulocyte-macrophage colony-stimulating factor on human basophilic cell differentiation. Blood 77: 971-979.
15. XIE, P., W. M. W. CHEUNG, F. C. F. IP, N. Y IP & M. F. LEUNG. 1997. Induction of TrkA receptor by retinoic acid in leukemia cell lines. Neuroreport 8:1067-1070.
16. BRODIE, C. & E. W. GELFAND. 1992. Functional nerve growth factor receptors on human B lymphocytes: Interaction with IL-2. J. Immunol. 148:3492-3497.
17. SCREPANTI, I., D. MECO, S. SCARPA, S. MORRONE, L. FRATI, A. GULINO & A. MODESTI. 1992. Neuromodulatory loop mediated by nerve growth factor and interleukin-6 in thymic stromal cell cultures. Proc. Natl. Acad. Sci. USA 89:3209-3212.
18. DAVIS, S., T. H. ALDRICH, D. M. VALENZUELA, V. WOXG, M. E. FURTH, S. P. SQUINTO & G. D. YANCOPOULOS. 1991. The receptor for ciliary neurotrophic factor. Science 253:59-63.
19. KISHLMOTO, T., S. AKIRA & T. TAGA. 1992. Interleukin-6 and its receptor: A paradigm for cytokines. Science 258:593-597.
20. BAZAN, J. F. 1991. Neuropoietic cytokines in the hematopoietic fold. Neuron 7:197-208.
21. IP, N. Y, S. N. NYE, T. G. BOULTON, G. PAVIS, T. TAGA, Y Li, S. J. BIRREN, K. YASUKAWA, T. KISHLMOTO, D. J. ANDERSON, N. STAHL. & G. D. YANCOPOULOS. 1992. CNTF and LIF act on neuronal cells via shared signalling pathways that involve the IL-6 signal transducing receptor component gp130. Cell 69:1121-1132.
22. IP, N. Y. & G. D. YANCOPOULOS. 1992. Ciliary neurotrophic factor and its receptor complex. Prog. Growth Factor Res. 4:139-155.
23. DAVIS, S., T. H. ALDRICH, N. STAHL, L. PAN, T. TAGA, T. KISHLMOTO, N. Y. IP & G. D. YANCOPOULOS. 1993. LIFRβ and gplSO as heterodimerizing signal transducers of the tripartite CNTF receptor. Science 260:1805-1808.
24. IP, N. Y, J. MCCLAIN, N. X. BARREZUETA, T. H. ALDRICH, L. PAN, Y. Li, S. J. WIEGAND, B. FRIEDMAN, S. DAVIS & G. D. YANCOPOULOS. 1993. The a component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Neuron 10:89-102.
25. STAHL, N., T. G. BOULTON, T. FARRUGGELLA, N. Y. IP, S. DAVIS, B. A. WITTHUHN, F. W. QUELLE, O. SILVENNOINEN, G. BARBIERI, S. PELLEGRINI, J. N. IHLE & G. D. YANCOPOULOS. 1994. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 βreceptor components. Science 263:92-95.
26. IP, N. Y, S. J. WlEGAND, J. MORSE & J. S. RUDGE. 1993. Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain. Eur. J. Neurosci. 5: 25-33.
27. ASADA, H., N. Y. IP, L. PAN, N. RAZACK, M. M. PARFITT & R. J. PLUNKETT. 1995. Time course of ciliary neurotrophic factor mRNA expression is coincident with the presence of protoplasmic astrocytes in traumatized rat striatum. J. Neurosci. Res. 40: 22-30.
28. PLUNKETT, R. J., N. Y. IP, H. ASADA, P. A. KASELOO & M. M. PARFITT. 1996. Trauma-induced expression of CNTF and BDNF messenger RNA in the striatum of hemiparkinsonian rats. Neuroreport, in press.
29. RUDGE, J. S., Y. Li, E. M. PASNIKOWSKI, K. MATTSSON, L. PAN, G. D. YANCOPOULOS, S. J. WIEGAND, R. M. LINDSAY & N. Y. IP. 1994. Neurotrophic factor receptors and their signal transduction capabilities in astrocytes. Eur. J. Neurosci. 6: 693-705.
30. DAVIS, S., T. H. ALDRICH, N. Y. IP, N. STAHL, S. SCHERER, T. FARRUGGELLA, P. S. DISTEFANO, R. CURTIS, N. PANAYOTATOS, H. GASCAN, S. CHEVALIER & G. D. YANCOPOULOS. 1993. Released form of CNTF receptor a component as a soluble mediator of CNTF responses. Science 259:1736-1739.
31. IP, F. C. F., A. K. Y. Fu, K. W. K. TSIM &N. Y. IP. 1995. Cloning of the a component of the chick ciliary neurotrophic factor receptor: Developmental expression and downregulation in denervated skeletal muscle. J. Neurochem. 65: 2393-2400.
32. IP, F. C. F., A. K. Y. Fu, K. W. K. TSIM &N. Y. IP. 1996. Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury. J. Neurochem. 67:1607-1612.
33. LIN, L.-F. H, D. MISMER, J. D. LILE, L. G. ARMES, E. T. BUTLER III, J. L. VANNICE &F. COLLINS. 1989. Purification, cloning and expression of ciliary neurotrophic factor (CNTF). Science 246:1023-1025.
34. SToCKLI, K. A., F. LOTTSPEICH, M. SENDTNER, P. MASIAKOWSKI, P. CARROLL, R. GOTZ, D. LINDHOLM &H. THOENEN. 1989. Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature 342:920-923.
35. IP, N. Y, P. C. MAISONPIERRE, R. ALDERSON, B. FRIEDMAN, M. E. FURTH, N. PANAYOTATOS, S. SQULNTO, G. D. YANCOPOULOS &R. M. LINDSAY. 1991. The neurotrophins and CNTF: Specificity of action towards PNS and CNS neurons. J. Physiol. Paris 85:123-130.
36. MANTHORPE, M., T. HAGG &S. VARON. 1992. Ciliary neurotrophic factor. In Neurotrophic Factors. J. A. Fallon, S. E. Loughlin, Eds.: 443-473. Academic Press. New York.
37. WONG, V., R. ARRIAGA, N. Y. IP &R. M. LINDSAY. 1993. The neurotrophins BDNF, NT-3, and NT-4, but not NGF, upregulate the cholinergic phenotype of developing motor neurons. Eur. J. Neurosci. 5:466-474.
38. SENDTNER, M, G. W. KREUTZBERG &H. THOENEN. 1990. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345:4401.
39. IP, N. Y., Y. Li, I. VAN DE STADT, N. PANAYOTATOS, R. F. ALDERSON &R. M. LINDSAY. 1991. Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures. J. Neurosci. 11: 3124-3134.
40. HAGG, T. &S. VARON. 1993. Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo. Proc. Natl. Acad. Sci. USA 90: 6315-6319.
41. MIYAJIMA, A., T. KITAMURA, N. HARADA, T. YOKOTA &K. ARAL 1992. Cytokine receptors and signal transduction. Annu. Rev. Immunol. 10:295-331.
42. CONOVER, J. C., N. Y. IP, W. T. POUEYMIROU, B. BATES, M. P. GOLDFARB, T. M. DECHIARA &G. D. YANCOPOULOS. 1994. Ciliary neurotrophic factor maintains the pluripotentiality of embryonic stem cells. Development 119:559-565.
43. GUPTA, S. K., A. J. HAGGARTY, S. CARBONETTO, R. J. RIOPELLE, P. M. RICHARDSON &R. J. DUNN. 1993. Eur. J. Neurosci. 5:977-985.
44. MASU, Y., E. WOLF, B. HOLTMANN, M. SENDTNER, G. BREM &H. THOENEN. 1993. Disruption of the CNTF gene results in motor neuron degeneration. Nature 365: 27-32.
45. TAKAHASHI, R., H. YOKOJI, H. MISAWA, M. HAYASHI, J. Hu &T. DEGUCHI. 1994. A null mutation in the human CNTF gene is not casually related to neurological diseases. Nature Genet. 7:79-84.
46. DECHIARA, T. M., R. VEJSADA, W. T. POUYEMIROU, A. ACHESON, C. SURI, J. C. COXOVER, B. FRIEDMAN, J. MCCLAIN, L. PAN, N. STAHL, N. Y. IP, A. KATO &G. D. YANCOPOULOS. 1995. Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. Cell 83:313-322.