Novel inhibitors against the transglutaminase-catalysed crosslinking of lens proteins

Experimental Eye Research

Volumn 66, Issue 5, 1998, Pages 531-536

  Lorand, Laszlo ^a   Stern, Andrew M ^b,c   Velasco, Pauline T ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c DUPONT COMPANY   (United States)

Author keywords

Calpain; Crosslinking; Crystallin; Inhibition; Lens; Transglutaminase

Indexed keywords

1,3 DIMETHYL 4,5 DIPHENYL 2 [(2 OXOPROPYL)THIO]IMIDAZOLIUM TRIFLUOROMETHYLSULFONATE; 1,3,4,5 TETRAMETHYL 2 [(2 OXOPROPYL)THIO]IMIDAZOLIUM; CALPAIN; CRYSTALLIN; DIMER; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; L 681777; L 683685; LENS PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATARACT; DRUG EFFECT; DRUG SELECTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RABBIT;

EID: 0032077093     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1997.0463     Document Type: Article

References (21)

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