Delay to first antipsychotic medication in schizophrenia: Impact on symptomatology and clinical course of illness

Journal of Psychiatric Research

Volumn 32, Issue 3-4, 1998, Pages 151-159

  Haas, G L ^a   Garratt, L S ^b   Sweeney, J A ^b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

NEUROLEPTIC AGENT;

ADULT; ARTICLE; DISEASE COURSE; FEMALE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHIZOIDISM; SCHIZOPHRENIA;

ADULT; ANTIPSYCHOTIC AGENTS; DISEASE PROGRESSION; FEMALE; HOSPITALIZATION; HOSPITALS, PSYCHIATRIC; HUMANS; MALE; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 0032075733     PISSN: 00223956     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3956(98)00008-9     Document Type: Article

References (23)

1. Andreasen NC. The Scale for the Assessment of Positive Symptoms (SAPS). Iowa City, IA, The University of Iowa, 1984.
2. Andreasen NC. Modified Scale for the Assessment of Negative Symptoms (SANS). Iowa City, The University of Iowa, 1984.
3. Anzai N, Okazaki Y, Miyauchi M, et al. Early neuroleptic medication within one year after onset can reduce risk of later relapses in schizophrenic patients. Annual Report of the Pharmacopsychiatric Research Foundation 1988;19:258-265.
4. Bleuler M. The Schizophrenic Disorders: Long-term Patient and Family Studies (Clemens SM, Trans.). New Haven, Yale University Press, 1978.
5. Cannon-Spoor H, Potkin SG, Wyatt RJ. Measurement of premorbid adjustment in chronic schizophrenia. Schizophr Bull 1982;8:470-484.
6. Crow TJ, MacMillan JF, Johnson AL, Johnstone EC. The Northwick Park study of first episodes of schizophrenia: II. A randomised controlled trial of prophylactic neuroleptic treatment. Br J Psychiatry 1986;148:120-127.
7. Endicott J, Spitzer RL, Fleiss JL, et al. The Global Assessment Scale: A procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry 1976;33:766-771.
8. Haas GL, Sweeney J. Premorbid and onset features of first-episode schizophrenia. Schizophr Bull 1992;18:373-386.
9. Liddle PF. Schizophrenic syndromes, cognitive performance and neurological dysfunction. Psychol Med 1987;17:49-57.
10. Loebel AD, Lieberman JA, Alvir JMJ, Mayerhoff DI, Geisler SH, Szymanski SR. Duration of psychosis and outcome in first-episode schizophrenia. Am J Psychiatry 1992;149:1183-1188.
11. May PR. Schizophrenia: A follow-up study of the results of five forms of treatment. Arch Gen Psychiatry 1981;38:776-784.
12. Olney JW. Excitatory amino acids and neuropsychiatric disorders. Biol Psychiatry 1989;26:505-525.
13. Olney JW. Excitotoxic amino acids and neuropsychiatric disorders. Am Rev Pharmacol Toxicol 1990;30:47-71.
14. Pelligrini-Giampietro DE, Cherici G, Noiani M, Carla V, Moroni F. Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. J Neurosci 1990;10:1035-1041.
15. Schooler NR, Goldberg SC, Boothe H, Cole JO. One year after discharge: Community adjustment of schizophrenic patients. Am J Psychiatry 1967:123:986-995.
16. Slivka A, Cohen G. Hydroxyl radical attack on dopamine. J Biol Chem 1985;260:15466-15472.
17. Sherry DF, Jacobs LF, Gaulin SJ. Spatial memory and adaptive specialization of the hippocampus. Trends in Neurosciences 1992;15:298-303.
18. Spitzer RL, Williams JBW, Gibbon M, First MB. Structured clinical interview for DSM-III-R - Patient Version (SCID-P) Biometrics Research Department, New York State Psychiatric Institute, 722 West 168th Street, New York, New York, 1988.
19. Waziri R, Baruah S, Hegwood T, Sherman AD. Abnormal serine hydroxymethyltransferase activity in the temporal lobes of schizophrenics. Neurosci Lett 1990;120:237-240.
20. Waziri R, Baruah S, Sherman AD. Abnormal serine-glycine metabolism in the brains of schizophrenics. Schizophrenia Res 1992;8:233-243.
21. Wirt RD, Werner S. Differential Treatment and Prognosis in Schizophrenia. 1959.
22. Wyatt RJ. Neuroleptics and the natural course of schizophrenia. Schizophr Bull 1991;17:325-351.
23. Wyatt RJ, Green MF, Tuma AH. Long-term morbidity associated with delayed treatment of first admission schizophrenic patients: A reanalysis of the Camarillo State Hospital data, Psychological Medicine, 1997;27:261-268.