Fluid administration attenuates the haemodynamic effect of frusemide in running horses

Equine Veterinary Journal

Volumn 30, Issue 3, 1998, Pages 246-250

  Hinchcliff, K W ^a   Mckeever, K H ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Atrial natriuretic peptide; Exercise induced pulmonary haemorrhage; Horse; Lasix

Indexed keywords

EQUIDAE; EQUUS CABALLUS;

ATRIAL NATRIURETIC FACTOR; DIURETIC AGENT; FUROSEMIDE; ISOTONIC SOLUTION; PLASMA PROTEIN; RINGER'S SOLUTION; SODIUM CHLORIDE;

ANIMAL; ANIMAL DISEASE; ANIMAL EXPERIMENT; ARTICLE; BLOOD VOLUME; BODY WEIGHT; CHEMICALLY INDUCED DISORDER; CROSSOVER PROCEDURE; DRUG EFFECT; FEMALE; FLUID THERAPY; HEART ATRIUM FUNCTION; HEART RATE; HEMATOCRIT; HEMODYNAMICS; HORSE; HORSE DISEASE; HYPOTENSION; LUNG WEDGE PRESSURE; PHYSIOLOGY;

ANIMALS; ATRIAL FUNCTION, RIGHT; ATRIAL NATRIURETIC FACTOR; BLOOD PROTEINS; BLOOD VOLUME; BODY WEIGHT; CROSS-OVER STUDIES; DIURETICS; FEMALE; FLUID THERAPY; FUROSEMIDE; HEART RATE; HEMATOCRIT; HEMODYNAMIC PROCESSES; HORSE DISEASES; HORSES; HYPOTENSION; ISOTONIC SOLUTIONS; PHYSICAL CONDITIONING, ANIMAL; PULMONARY WEDGE PRESSURE; SODIUM CHLORIDE;

EID: 0032066234     PISSN: 04251644     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-3306.1998.tb04495.x     Document Type: Article

References (28)

1. Bourland, W.A., Day, D.K. and Williamson, H.E. (1977) The role of the kidney in the early nondiuretic action of furosemide to reduce elevated left atrial pressure in the hypervolemic dog. J. Pharmaco. Expt. Ther. 202, 221-229.
2. Cooley, J.L., Hinchcliff, K.W., McKeever, K.H., Lamb, DR. and Muir, W.W (1994) Effect of furosemide on plasma atrial natriuretic peptide and aldosterone concentrations and renin activity in running horses. Am. J. vet. Res. 55, 273-277.
3. Edwards, B.S., Zimmerman, R.S., Schwab, TYR., Heublein, D.M. and Burnett, J.C. (1988) Atrial stretch, not pressure, is the principal determinant controlling the acute release of atrial natriuretic factor. Circ. Res. 62, 191-195.
4. Erickson, B.K , Erickson, H.H. and Coffman, J R. (1990) Pulmonary artery, aortic and oesophageal pressure changes during high intensity treadmill exercise in the horse: a possible relation to exercise-induced pulmonary hemorrhage, Equine vet. J., Suppl. 9, 47-52.
5. Freestone, J E., Carlson, G.P., Harrold, D.R. and Church, G (1988) Influence of furosemide treatment on fluid and electrolyte balance in horses. Am. J. vet. Res. 49, 1899-1902.
6. Glantz, S.A. and Slinker, B.K. (1990) Primer of Regression and Analysis of Variance McGraw-Hill Inc., New York, pp 381-460.
7. Greenberg, S., McGowan, C., Xie, J. and Summer, W.R. (1994) Selective pulmonary and venous smooth muscle relaxation by furoseimde: a comparison with morphine. J. Pharmacol. expt. Therap. 270, 1077-1085.
8. Hinchcliff, K.W. and Mitten, L.A. (1993) Furosemide, bumetanide and ethacrynic acid. Vet. Clin. N. Am.: Equine Pract. 3, 511-522.
9. Hinchcliff, K.W, McKeever, K H. and Muir, W.W. (1991) Furosemide-induced changes in plasma and blood volume in horses. J. vet. Pharmacol. Therap. 14, 411-417.
10. Hinchcliff, K.W., McKeever, K.H., Muir, W.W and Sams, R.A. (1995) Pharmacologic interaction of furosemide and phenylbutazone in horses. Am. J. vet Res. 56, 1206-1212.
11. Hinchcliff, K W., Hubbell, J.A.E., Grosenbough, D., Mitten, L.A. and Beard, W.L. (1996) Hemodynamic effects of furosemide are dependent on diuresis. Proc. Am. Ass. equine Practnrs. 42, 229-230.
12. Hopper, M.K., Pieschl Jr., R.L., Pelletier, N.G and Erickson, H.H, (1991) Cardiopulmonary effects of acute blood volume alteration prior to exercise. In: Equine Exercise Physiology 3. Eds: S.G.B. Persson, A. Lindholm and L.B. Jeffcott. ICEEP Publications, Davis. pp 9-16.
13. Johnston, G.D., Hiatt W R., Neis, A.S., Payne, N.A., Murphy, R.C. and Gerber, I.G. (1983) Factors modifying the early nondiurtic vascular effects of furosemide in man. The possible role of renal prostaglandins. Circ. Res. 53, 630-635.
14. Langsetmo, I., Meyer Tammi, S., Fedde, M.R and Erickson, H.E. (1996) Relationship between pulmonary vascular pressure and pulmonary hemorrhage in horses: is there a threshold value? Proc. Am. Ass. equine Practnrs. 42, 227-228.
15. Lindinger, M.I., and Ecker, G.L (1995) Ion and water losses from body fluids during a 163 km endurance ride Equine vet. J., Suppl. 18 (Equine Exercise Physiology IV), 314-322
16. Lundergan, C.F., Fitzpatrick, T.M., Rose, J C , Ramwell, P W. and Kot, P.A. (1988) Effect of cyclooxygenase inhibition on the pulmonary vasodilator response to furosemide. J. Pharmacol Expt. Ther. 246, 102-106.
17. Manohar, M., Hutchens, E. and Coney, E. (1993) Pulmonary haemodynamics in the exercising horse and their relationship to exercise-induced pulmonary haemorrhage Br. vet. J. 149, 419-428.
18. McKeever, K.H., Hinchcliff, K.W., Schmall, L.M., Lamb, D.R. and Muir, W.W. (1991 a) Atrial natriuretic peptide during exercise in horses. In: Equine Exercise Physiology 3. Eds: S.G.B. Persson, A. Lindholm and L.B. Jeffcott ICCEP Publications, Sweden. pp 368-373.
19. McKeever, K.H., Hinchcliff, K.W and Cooley, J.L. (1991b) Acute volume load during exercise in horses: atrial natriurctic factor, vasopressing and hemodynamics. Med. Sci Sports Exercise 23, S104 (Abstr.).
20. McKeever, K.H., Hinchcliff, K W., Reed, S.M. and Robertson, J T.R. (1993) Role of decreased plasma volume in hematocrit alterations during incremental treadmill exercise in horses. Am. J. Physiol 265, R404-R408.
21. McKeever, K.H., Hinchcliff, K W., Cooley, J.L , Lamb, D.R. and Muir, W.W. (1992) Arterial-venous difference in atrial natriuretic peptide concentration during exercise in horses. J. Am. vet. med. Ass. 53, 2174-2177.
22. Mitten, L.A , Hinchcliff, K.W. and Pate, J.L. (1996) Phenylbutazone increases right atnal pressure and heart rate of running horses. J. appl. Physiol. 81, 312-317.
23. Muir, W.W, Kohn, C.W. and Sams, R. (1978) Effects of furosemide on plasma volume and extracellular fluid volume in horses. Am. J. vet. Res. 39, 1688-1691.
24. Muir, W.W., Milne, D.W and Skarda, R.T. (1976) Acute hemodynamic effects of furosemide administered intravenously in the horse. Am. J vet. Res. 37, 1177-1180.
25. Olsen, S.C , Coyne, C.P., Lowe, B S., Pelletier, N., Raub, E.M and Erickson, H.H. (1992) Influence of furosemide on hemodynamic responses during exercise in horses. Am. J. vet Res. 53, 742-747
26. Paseoe, J.R. (1996) Exercise induced pulmonary hemorrhage: a unifying concept Proc. Am. Ass. equine Practnrs 42, 220-226.
27. Rivas, R.J. and Hinchcliff, K.W. (1997) Effect of furosemide and fluid administration on blood volume and right atrial pressure of horses. Am. J. vet. Res. 58, 632-635.
28. Tobin, T., Roberts, B L., Swercek, T.W and Crisman, M. (1978) The pharmacology of furosemide in the horse. III. Dose and time response relationships, effects of repeated dosing, and performance effects. J. equine Med. Surg 2, 216-226.