Effects of Exercise at Different Ages on Bone Density and Mechanical Properties of Femoral Bone of Aged Mice

Tohoku Journal of Experimental Medicine

Volumn 185, Issue 1, 1998, Pages 15-24

  Hoshi, Akio ^a,b   Watanabe, Hiromi ^b   Chiba, Momoko ^b   Inaba, Yutaka ^b  

^a NIPPON DENTAL UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone density; Ca metabolism; Mechanical properties of the bone; Voluntary exercise

Indexed keywords

CALCITONIN; CALCIUM; PARATHYROID HORMONE; PHOSPHORUS;

AGING; ANIMAL; ANIMAL EXPERIMENT; ARTICLE; BIOMECHANICS; BLOOD; BODY WEIGHT; BONE DENSITY; FEMALE; FEMUR; INSTITUTE FOR CANCER RESEARCH MOUSE; MOUSE; PHYSIOLOGY; TENSILE STRENGTH;

AGING; ANIMALS; BIOMECHANICS; BODY WEIGHT; BONE DENSITY; CALCITONIN; CALCIUM; FEMALE; FEMUR; MICE; MICE, INBRED ICR; PARATHYROID HORMONE; PHOSPHORUS; PHYSICAL CONDITIONING, ANIMAL; TENSILE STRENGTH;

EID: 0032065428     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.185.15     Document Type: Article

References (22)

1. Aloia, J.F., Cohn, S.H., Ostuni, J., Cane, R. & Ellis, K. (1978) Prevention of involutional bone loss by exercise. Ann. Intern. Med., 89, 356-358.
2. Aoki, H., Okayama, S., Kondo, K. & Akao, M. (1993) Effect of exercise on strength and chemical composition of rat femur bone. Biomed. Mater. Eng., 3, 25-31.
3. Blalir, S.N., Kohl, H.W., Gordon, N.F. & Paffenbarger, R.S., Jr. (1992) How much physical activity is good for health? Annu. Rev. Public Health, 13, 99-126.
4. Bourrin, S., Ghaemmaghami, F., Vico, L., Chappard, D., Gharib, C. & Alexandre, C. (1992) Effect of five-week swimming program on rat bone: A histomorphometric study. Calcif. Tissue Int., 51, 137-142.
5. Burstein, A.H., Zika, J.M., Heiple, K.G. & Klein, L. (1975) Contribution of collagen and mineral to the elastic-plastic properties of bone. Am. J. Bone Joint Surg., 57, 956-961.
6. Detenbeck, L.C. & Jowsey, J. (1969) Normal aging in the bone of the adult dog. Clin. Orthop., 65, 76-80.
7. Hoshi, A., Kanaba, A. & Matsuda, K. (1990) Effect of physical activity on calcium metabolism in middle elder aged female. Bull. Physiol. Fit. Research Inst., 75, 119-128. (in Japanese)
8. Hoshi, A., Watanabe, H., Chiba, M. & Inaba, Y. (1996) Effects of swimming and weight loading on bone density and mechanical properties of the mouse femoral bone. Environ. Health Prev. Med., 1, 128-132.
9. Hoshi, A., Watanabe, H., Chiba, M. & Inaba, Y. (1998) Bone density and mechanical properties in femoral bone of swim loaded aged mice. Biomed. Environ. Sci., (in press)
10. Jacobson, P.C., Beaver, W., Grubb, S.A., Taft, T.N. & Talmadge, R.V. (1984) Bone density in women: College athletes and older athletic women. J. Orthop. Res., 2, 328-332.
11. Koyama, H. & Nishizawa, Y. (1993) Body weight as a determinant of bone mineral. Igakunoayumi, 165, 601-605. (in Japanese)
12. 3 administered in vivo on phospahte uptake by isolated chick renal cells. Am. J. Physiol., 242, C312-C318.
13. Matsushita, M., Tsuboyama, T., Kasai, R., Okumura, H., Yamamuro, T., Higuchi, K., Kohno, A., Yonezu, T., Utani, A., Umezawa, M. & Takeda, T. (1986) Age-related changes in bone mass in the senescence-accelerated mouse (SAM). Am. J. Pathol., 12, 276-283.
14. Mazess, R.B. (1987) Bone density in diagnosis of osteoporosis. Calcif. Tissue Int., 41, 117-118.
15. Miyanaga, Y. (1979) Measurement of strenght and viscoelasticity of subchondral bone. Orthopedic. Surg., 30, 119-1205. (in Japanese)
16. Nishida, H., Matsui, H. & Sugiura, H. (1992) Effects of exercise and calcium-intake on bone hardness and bone constituents in aged mice. Jpn. J. Public Health., 39, 205-213. (in Japanese)
17. Okumura, H., Yamamoto, T., Kasai, R., Ichisaka, A., Hatashi, Y., Matsusita, M. & Takeshita, K. (1984) Microdensitometrical analysis of the bone of experimental animals. Bone Morphometry, 3, 99-109. (in Japanese)
18. Orimo, H. (1996) Recent findings in osteoporosis research. Juntendo Med. J., 42, 2-12. (in Japanese)
19. Riggs, B.L. & Melton, L.J. III. (1986) Involutional osteoporosis. N. Engl. J. Med., 314, 1676-1686.
20. Rubin, C.T., Bain, S.D. & McLead, K.J. (1992) Suppression of the osteogenic response in the skeleton. Calcif. Tissue Int., 50, 306-313.
21. Suzuki, K., Machida, K., Kuriyama, T. & Sugawara, K. (1994) Preventive effects of long-term voluntary exercise on a variety of diseases and their mechanisms in laboratory animals studies: A review. Hum. Sci. Res., 3, 127-142. (in Japanese)
22. Tokuyama, K., Saito, M. & Okuda, H. (1982) Effects of wheel running on food intake and weight gain of male and female rats. Physiol. Behav., 28, 899-903.