The Effects of Dexamethasone Immunosuppression on Turkey Osteomyelitis Complex in an Experimental Escherichia coli Respiratory Infection

Poultry Science

Volumn 77, Issue 5, 1998, Pages 654-661

  Huff, G R ^a   Huff, W E ^a   Balog, J M ^a   Rath, N C ^a  

^a UNIVERSITY OF ARKANSAS   (United States)

Author keywords

Dexamethasone; Escherichia coli; Immunosuppression; Turkey osteomyelitis complex

Indexed keywords

DEXAMETHASONE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIRD DISEASE; BODY WEIGHT; DRUG EFFECT; ENTEROBACTER INFECTION; HEART MUSCLE; IMMUNOSUPPRESSIVE TREATMENT; LIVER; MALE; MORTALITY; ORGAN SIZE; OSTEOMYELITIS; PATHOLOGY; SPLEEN; TURKEY (BIRD);

ANIMALS; BODY WEIGHT; DEXAMETHASONE; ESCHERICHIA COLI INFECTIONS; IMMUNOSUPPRESSION; LIVER; MALE; MYOCARDIUM; ORGAN SIZE; OSTEOMYELITIS; POULTRY DISEASES; SPLEEN; TURKEYS;

EID: 0032063736     PISSN: 00325791     EISSN: None     Source Type: Journal    
DOI: 10.1093/ps/77.5.654     Document Type: Article

References (39)

1. Anderson, R. J., L. A. Schafer, D. B. Olin, and T. C. Eickhoff, 1973. Infectious risk factors in the immunosuppressed host. Am. J. Med. 54:453-460.
2. Barnes, H. J., S. C. Clark, and B. J. Tilley, 1990. Green liver/ osteomyelitis complex in turkeys: an overview. Pages 73-77 in: Proceedings of the Avian Skeletal Disease Symposium. AAAP/AVMA. San Antonio, TX.
3. Bayyari, G. R., W. E. Huff, R. A. Norton, J. K. Skeeles, J. N. Beasley, N. C. Rath, and J. M. Balog, 1994. A longitudinal study of green-liver osteomyelitis complex in commercial turkeys. Avian Dis. 38:744-754.
4. Bayyari, G. R., W. E. Huff, N. C. Rath, J. M. Balog, L. A. Newberry, J. D. Villines, and J. K. Skeeles, 1997a. Immune and physiological responses of turkeys with green-liver osteomyelitis complex. Poultry Sci. 76:280-288.
5. Bayyari, G. R., W. E. Huff, N. C. Rath, J. M. Balog, L. A. Newberry, J. D. Villines, J. K. Skeeles, N. B. Anthony, and K. E. Nestor, 1997b. Effect of the genetic selection of turkeys for increased body weight and egg production on immune and physiological responses. Poultry Sci. 76: 289-296.
6. Bayyari, G. R., W. E. Huff, J. M. Balog, and N. C. Rath, 1997c. Variation in toe-web response of turkey poults to phytohemagglutinin-P and their resistance to respiratory infection and turkey osteomyelitis complex in an Escherichia coli challenge model. Poultry Sci. 76:791-797.
7. Campbell, T. W., 1988. Avian Hematology. Iowa State University Press, Ames, IA.
8. Clark, S. R., H. J. Barnes, A. A. Bickford, R. P. Chin, and R. Droual, 1991. Relationship of osteomyelitis and associated soft-tissue lesions with green liver discoloration in torn turkeys. Avian Dis. 35:139-146.
9. Cook, R. E., 1988. Turkey osteomyelitis-synovitis complex. Inspection standards and procedures. Technical Services, Food Safety and Inspection Service. USDA, National Agricultural Library, Washington, DC.
10. Corrier, D. E., and J. R. DeLoach, 1989. Evaluation of cell-mediated cutaneous basophil hypersensitivity in young chickens by an interdigital skin test. Poultry Sci. 69: 403-408.
11. Droual, R., R. P. Chin, and M. Rezvani. 1996. Synovitis, osteomyelitis, and green liver in turkeys associated with Escherichia coli. Avian Dis. 40:417-424.
12. Duncan, D. B., 1955. Multiple range and multiple F tests. Biometrics 11:1-42.
13. Graham, B. S., and W. S. Tucker, Jr., 1984. Opportunistic infections in endogenous Cushing's syndrome. Ann. Intern. Med. 101:334-348.
14. Gross, W. B., and H. S. Siegel, 1983. Evaluation of the heterophil/lymphocyte ratio as a measure of stress in chickens. Avian Dis. 27:972-979.
15. Gross, W. B., P. B. Siegel, and R. T. DuBose, 1980. Some effects of feeding corticosterone to chickens. Poultry Sci. 59: 516-522.
16. Gustafson, T. L., W. Schaffner, G. B. Lavely, C. W. Stratton, H. K. Johnson, and R. H. Hutcheson, Jr., 1983. Invasive aspergillosis in renal transplant recipients: correlation with corticosteroid therapy. J. Infect. Dis. 148:230-238.
17. Hart, W. M., and H. E. Essex, 1942. Water metabolism of the chicken with special reference to the role of the cloaca. Am. J. Physiol. 336:657.
18. Hester, H. R., H. E. Essex, and F. C. Mann, 1940. Secretion of urine in the chicken. Am. J. Physiol. 128:592.
19. Isobe, T., and H. S. Lillehoj, 1992. Effects of corticosteroids on lymphocyte subpopulations and lymphokine secretion in chickens. Avian Dis. 36:590-596.
20. Isobe, T., and H. S. Lillehoj, 1993. Dexamethasone suppresses T cell-mediated immunity and enhances disease susceptibility to Eimeria mivati infection. Vet. Immun. Immunopathol. 39:431-446.
21. Long, P. L., and M. E. Rose, 1970. Extended schizogony of Eimeria mivati in betamethasone-treated chickens. Parasitology 60:147-155.
22. McCaskey, P. C., 1989. Incidence and pathogenesis of the osteomyelitis-synovitis complex in turkeys and its association with abnormally green livers. J. Am. Vet. Med. Assoc. 194:1789.
23. McGruder, E. D., M. H. Kogut, D. E. Corrier, J. R. DeLoach, and B. M. Hargis, 1995. Interaction of dexamethasone and Salmonella enteritidis immune lymphokines on Salmonella enteritidis organ invasion and in vitro polymorphonuclear leukocyte function. FEMS Immunol. Med. Microbiol. 11: 25-34.
24. Mutalib, A., C. Riddell, and A. D. Osborne, 1982. Studies on the pathogenesis of Staphylococcal osteomyelitis in chickens. Effect of stress on experimentally induced osteomyelitis. Avian Dis. 27:141-156.
25. Mutalib, A., B. Miguel, T. Brown, and W. Maslin, 1996. Distribution of arthritis and osteomyelitis in turkeys with green liver discoloration. Avian Dis. 40:661-664.
26. National Research Council, 1994. Nutrient Requirements of Poultry. 9th rev. ed. National Academy Press, Washington, DC.
27. Piercy, D.W.T., and B. West, 1976. Experimental Escherichia coli infection in broiler chickens: course of the disease induced by inoculation via the air sac route. J. Comp. Pathol. 86: 203-210.
28. Redig, P. T., J. L. Dunnette, L. Mauro, V. Sivanandan, and F. Markham, 1985. The in vitro response of turkey lymphocytes to steroid hormones. Avian Dis. 29:373-383.
29. Rose, M. E., 1970. Immunity to coccidiosis: effect of betamethasone treatment of fowls on Eimeria mivati infection. Parasitology 60:137-146.
30. Roth, J. A., and K. P. Flaming, 1990. Model systems to study immunomodulation in domestic food animal. Pages 21-41 in: Immunomodulation in Domestic Food Animals. F. Blecha and B. Charley, ed. Academic Press, Inc., San Diego, CA.
31. SAS Institute, 1988. SAS/STAT® User's Guide. 1988 edition. SAS Institute Inc., Cary, NC.
32. Schaffner, A., 1985. Therapeutic concentrations of glucocorticoids suppress the antimicrobial activity of human macrophages without impairing their responsiveness to gamma interferon. J. Clin. Inv. 76:1755-1764.
33. Schaffner, A., and T. Schaffner, 1988. Glucocorticoid-induced impairment of macrophage antimicrobial activity: mechanisms and dependence of the state of activation. Pages 212-221 in: Perspectives on Bacterial Pathogenesis and Host Defense. B. Urbaschek, ed. The University of Chicago Press, Chicago, IL.
34. Scheinman, R. I., P. C. Cogswell, A. K. Lofquist, and A. S. Baldwin, Jr., 1995. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 270:283-286.
35. Siegel, H. S., 1980. Physiological stress in birds. Bioscience 30: 529-534.
36. Siegel, H. S., and M. Van Kampen, 1984. Energy relationships in growing chickens given daily injections of corticosterone. Br. Poult. Sci. 25:477-485.
37. Tilley, B. J., and H. J. Barnes, 1990. Factors associated with green livers in turkeys. Page 46 in: Proceedings of the Western Poultry Disease Conference. Sacramento, CA.
38. Westerhof, I., W. E. Van den Brom, and J. A. Mol, 1996. Responsiveness of the glucocorticoid-suppressed pituitaryadrenocortical system of pigeons (Columba livia domestica) to stimulation with arginine vasopressin. Avian Dis. 40: 312-320.
39. Yamamoto, Y., and H. Friedman, 1996. Steroids and infection. Pages 173-194 in: Psychoneuroimmunology, Stress, and Infection. H. Friedman, T. W. Klein, and A. L. Friedman, ed. CRC Press, Boca Raton, FL.