Endocrinological and Polysomnographic Findings in Kleine-Levin Syndrome: No Evidence for Hypothalamic and Circadian Dysfunction

Sleep

Volumn 21, Issue 3, 1998, Pages 278-284

  Mayer, G ^a,c   Leonhard, E ^a   Krieg, J ^b   Meier Ewert, K ^a  

^a Hephata Klinik Schwalmstadt Treysa   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c Hephata Klinik   (Germany)

Author keywords

Actimetry; Circadian rhythm; Endocrinology; Kleine Levin syndrome; Sleep structure

Indexed keywords

FOLLITROPIN; HUMAN GROWTH HORMONE; HYDROCORTISONE; MELATONIN; PROLACTIN; THYROTROPIN;

ADOLESCENT; ADULT; ARTICLE; BLOOD; CIRCADIAN RHYTHM; FEMALE; HUMAN; HYPERSOMNIA; HYPOTHALAMUS; MALE; METHODOLOGY; PHYSIOLOGY; POLYSOMNOGRAPHY; REM SLEEP;

ADOLESCENT; ADULT; CIRCADIAN RHYTHM; FEMALE; FOLLICLE STIMULATING HORMONE; HUMAN GROWTH HORMONE; HUMANS; HYDROCORTISONE; HYPOTHALAMUS; KLEINE-LEVIN SYNDROME; MALE; MELATONIN; POLYSOMNOGRAPHY; PROLACTIN; SLEEP, REM; THYROTROPIN;

EID: 0032063530     PISSN: 01618105     EISSN: None     Source Type: Journal    
DOI: 10.1093/sleep/21.3.278     Document Type: Article

References (24)

1. Smolik P, Roth B. Kleine-Levin syndrome, ethiopathogenesis and treatment. Acta Universitatis Carolinae Medica - Monographia CXXVI-II 1988.
2. Roth B, and Nevsimalová S. The clinical picture of periodic hypersomnia. Sleep 1980. 5th Eur Congr Sleep Res, Amsterdam 1980:120-124. Karger, Basel 1981.
3. Billiard M, Cadilhac J. Les hypersomnies récurrentes. Rev Neurol 1988;144(4):249-258.
4. Billiard M, Guilleminault C, Dement WC. A menstruation-linked periodic hypersomnia. Neurology 1975;25:436-443
5. Critchley M. Periodic hypersomnia and megaphagia in adolescent males. Brain 1962;85:627-656.
6. Critchley M, Hoffman HL. Syndrome of periodic somnolence and morbid hunger. Br Med J 1942;1: 137-9.
7. Fröscher W, Maier V, Fritsch TH. Periodic hypersomnia: case report with biochemical and EEG findings. Sleep 1991;14(5):460-463.
8. Russel J, Grunstein R. Kleine-Levin syndrome: a case report. Australian and New Zealand Journal of Psychiatry 1992;26:119-123.
9. Waldhauser F, Lieberman H., Lynch H, et al. A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol. Neuroendocrinology 1987;46:125-30.
10. Lemire I. Revue du syndrome de Kleine-Levin: vers une approche intégrée. Revue can de psychiatrie 1993;38:277-284.
11. Chesson AL., Levine SN., Kong LS. and Lee SC. Neuroendocrine evaluation in Kleine-Levin Syndrome: evidence of reduced dopaminergic tone during periods of hypersomnolence. Sleep 1991;14(3):226-232.
12. Gadoth,N, Dickerman Z, Bechar M, Laron Z and Lavie P. Episodic hormone secretion during sleep in Kleine-Levin Syndrome: evidence for hypothalamic dysfunction. Brain Dev 1987;9:309-315.
13. Kloß W, Meier-Ewert K. Das Kleine-Levin Syndrom - eine funktionelle Zwischenhirnstörung? Psycho 1983:602-608.
14. Carpenter S, Yassa R. and Ochs R. A pathologic basis for KleineLevin Syndrome. Arch Neuro 1982;39:125-128.
15. Fenzi F, Simonati A., Crosato F, Ghersini L and Rizzuro, N. Clinical features of Kleine-Levin Syndrome with localized encephalitis. Neuropediatrics 24, 1993:292-295.
16. Takrani LB, Cronin D. Kleine-Levin syndrome in a female patient. Can Psychiatr Assoc J 1965;21:315-8.
17. Lavie P, Gadoth N, Gordon CR, Goldhammer G, Bechar M. Sleep patterns in Kleine-Levin syndrome. Electoenceph Clin Neurophysiol 1979;47:369-71.
18. Reynolds CF, Kupfer DJ, Christiansen CL, Auchenbach R. Brenner RP, Sewitch DE, Taska LS, Coble PA. Multiple sleep latency test findings in Kleine-Levin Syndrome. J Nerv Ment Dis 1984;172:41-44.
19. Hishikawa Y. Ijima S, Tashiro T, Sugita Y, Teshima Y, Matsuo R and Kaneda H. Polysomnographic findings and growth hormone secretion in patients with periodic hypersomnia. Sleep 1980. 5th Eur Congr Sleep Res Amsterdam 1980:128-133.
20. Romero O, Sagalés T, Gimeno V and Cordoba J. Phase advancement of slow-wave sleep in a patient with periodic hypersomnia. Sleep 1995;18(3):206-208.
21. Burton SA. Recovery from sleep attacks" in Kleine-Levin Syndrome may involve a process of gradual phase advance. Abstract APSS Congress 1994.
22. Thompson C, Obrecht R, Franey C, Arendt J, Checkley SA. Neuroendocrine rhythms in a patient with the Kleine-Levin syndrome. British Journal of Psychiatry 1985;147:440-43.
23. Kerkhofs M., Van Cauter E., Von Onderbergen A., Caufriez A., Thorner MO. and Copinschi G Sleep-promoting effects of growth hormone-releasing hormone in normal men. Am J Physiol 1993;264:E594-E598.
24. Dawson D, Encel N. Melatonin and sleep in humans. J Pineal Res 1993;15:1-12.