Mechanical characterization of an in vitro device designed to quantitatively injure living brain tissue

Annals of Biomedical Engineering

Volumn 26, Issue 3, 1998, Pages 381-390

  Morrison III, Barclay ^a   Meaney, David F ^a   McIntosh, Tracy K ^a,b,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NONE   (United States)

Author keywords

Cell culture; Dynamic loading; Mechanical stimulus; Stretch injury

Indexed keywords

ARTICLE; BIOLOGICAL MODEL; BRAIN INJURY; CELL CULTURE; COMPUTER PROGRAM; CULTURE TECHNIQUE; ELASTICITY; INSTRUMENTATION; MECHANICAL STRESS; PATHOLOGY; SIGNAL PROCESSING; VISCOSITY;

BRAIN INJURIES; CELLS, CULTURED; CULTURE TECHNIQUES; ELASTICITY; MODELS, NEUROLOGICAL; SIGNAL PROCESSING, COMPUTER-ASSISTED; SOFTWARE; STRESS, MECHANICAL; VISCOSITY;

EID: 0032063408     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1114/1.61     Document Type: Article

References (39)

1. Adams, J. H., D. I. Graham, L. S. Murray, and G. Scott. Diffuse axonal injury due to nonmissile head injury in humans: An analysis of 45 cases. Ann. Neurol. 12:557-563, 1981.
2. Adkins, J. E., and R. S. Rivlin. Large elastic deformations of isotropic materials IX. The deformation of thin shells. Philos. Trans. R. Soc. London, Ser. A 244:505-531, 1952.
3. Balentine, J. D., W. B. Greene, and M. Bornstein. In vitro spinal cord injury. Lab. Invest. 58:93-99, 1988.
4. Brodland, G. W. Highly non-linear deformations of uniformly-loaded circular plates. Int. J. Solids Struct. 24:351-362, 1988.
5. 2-], in NG 108-15 cells subjected to high strain rate deformation and chemical hypoxia: An in vitro model for neural trauma. J. Neurotrauma. 13:396-407, 1996.
6. Christman, C. W., M. S. Grady. S. A. Walker, K. L. Holloway, and J. T. Povlishock. Ultrastructural studies of diffuse axonal injury in humans. J. Neurotrauma 11:173-186, 1994.
7. Ellis, E. F., J. S. McKinney, K. A. Willoughby, S. Liang, and J. T. Povlishock. A new model for rapid stretch-induced injury of cells in culture: Characterization of the model using astrocytes. J. Neurotrauma 12:325-339, 1995.
8. Galbraith, J. A., L. E. Thibault, and D. R. Matteson, Mechanical and electrical responses of the giant squid axon to simple elongation. J. Biomech. Eng. 115:13-22, 1993.
9. Gennarelli, T. A. Animate models of head injury. J. Neurotrauma 11:357-368, 1994.
10. Gennarelli, T. A., L. E. Thibault, J. H. Adams, D. I. Graham, C. J. Thompson, and R. P. Marcincin. Diffuse axonal injury and traumatic coma in the primate. Ann. Neurol 12:564-574, 1982.
11. Gorfien, S. F., F. K. Winston, L. E. Thibault, and E. J. Macarak. Effects of biaxial deformation on pulmonary endothelial cells. J. Cell Physiol. 139:492-500, 1989.
12. Hart-Smith, L. J. Elasticity parameters for finite deformations of rubber-like materials. Z. Angew. Math. Phys. 17:608-626, 1966.
13. Hart-Smith, L. J., and J. D. C. Crisp. Large elastic deformations of thin rubber membranes. Int. J. Eng. Sci. 5:1-24, 1967.
14. Kirkpatrick, J. B., M. L. Higgins, J. H. Lucas, and G. W. Gross. In vitro simulation of neural trauma by laser. J. Neuropathol. Exp. Neurol. 44:268-284, 1985.
15. Klingbeil, W. W., and R. T. Shield. Some numerical investigations on empirical strain energy functions in the large axi-symmetric extensions of rubber membranes. Z. Angew. Math. Phys. 15:608-629, 1964.
16. Koeneman. J. B. Viscoelastic properties of brain tissue. MS thesis. Case Institute of Technology, Cleveland, OH, 1966.
17. LaPlaca, M. C., V. M. Lee, and L. E. Thibault. An in vitro model of traumatic neuronal injury: Loading rate-dependent changes in acute cytosolic calcium and lactate dehydrogenase release. J. Neurotrauma 14:355-368, 1997.
18. LaPlaca, M. C., and L. E. Thibault. An in vitro traumatic injury model to examine the response of neurons to a hydro-dynamically induced deformation. Ann. Biomed. Eng. 25:665-677, 1997.
19. Lucas, J. H. In vitro models of mechanical injury. J. Neurotrauma 9:117-121, 1992.
20. Lucas, J. H., and A. Wolf. In vitro studies of multiple impact injury to mammalian CNS neurons: prevention of perikaryal-damage and death by ketamine. Brain Res. 543:181-193, 1991.
21. Margulies, S. S. Biomechanics of traumatic coma in the primate. Ph.D. Thesis, University of Pennsylvania, Philadelphia, PA, 1990.
22. Margulies, S. S., L. E. Thibault, and T. A. Gennarelli. Physical model simulations of brain injury in the primate. J. Biomech. 23:823-836, 1990.
23. McKinney, J. S., K. A. Willoughby, S. Liang, and E. F. Ellis, Stretch-induced injury of cultured neuronal, glial. and endothelial cells: Effect of polyethelene glycol-conjugated superoxide dismutase. Stroke 27:934-940, 1996.
24. Meaney, D. F. Biomechanics of acute subdural hematoma in the subhuman primate and man. Ph.D. Thesis, University of Pennsylvania. Philadelphia, PA. 1991.
25. Meaney, D. F., and L. E. Thibault. Physical model studies of cortical brain deformation in response to high strain rate inertial loading. In: International Conference on the Biomechanics of Impacts. Lyon. France: IRCOBI, 1990, pp. 215-224.
26. Murphy, E. J., and L. A. Horrocks. A model for compression trauma: pressure induced injury in cell cultures. J. Neurotrauma. 10:431-444, 1993.
27. Oppenheimer. D. R. Microscopic lesions in the brain following head injury. J. Neurol. Neurosurg. Psychiatry 31:299-306, 1968.
28. Pamidi, M. R., and S. H. Advani. Nonlinear constitutive relations for human brain tissue. J. Biomech. Eng. 100:44-48, 1978.
29. Press, W. H., S. A. Teukolsky, W. T. Vetterling, and B. P. Flannery. Statistical description of Data. In: Numerical Recipes in C, the Art of Scientific Computing. Cambridge, MA: Cambridge University Press, 1992. pp. 609-655.
30. Rand, C. W., and C. B. Courville. Histological changes in the brain in cases of fatal injury to the head. Arch. Neurol. Psychiatry 31:526-555, 1934.
31. Regan, R. F., and D. W. Choi. The effect of NMDA, AMPA/ kainate, and calcium channel antagonists on traumatic cortical neuronal injury in culture. Brain Res. 633:236-242, 1994.
32. Reissner, E. On finite deflections of circular plates. In: Proceedings of Symposia in Applied Mathematics of the American Mathematical Society. New York: American Mathematical Society, 1949, pp. 213-219.
33. Shepard, S. R., J. B. G. Ghajar, R. Giannuzzi, S. Kupferman, and R. J. Hariri. Fluid percussion barotrauma chamber: A new in vitro model for traumatic brain injury. J. Surg. Res. 51:417-424, 1991.
34. Shuck, L. Z., and S. H. Advani. Rheological response of human brain tissue in shear. Trans. ASME, J. Basic Eng. 12:905-911, 1972.
35. Tavalin, S. J., E. F. Ellis, and L. S. Satin. Mechanical perturbation of cultured cortical-neurons reveals a stretch-induced delayed depolarization. J. Neurophysiol 74:2767-2773, 1995.
36. Thibault, L. E., and D. L. Fry. Mechanical characterization of membranelike biological tissue. J. Biomech. Eng. 105:31-38, 1983.
37. Wang, H. C., and A. S. Wineman. A mathematical model for the determination of viscoelastic behavior of brain in vivo- I oscillatory response. J. Biomech. 5:431-446, 1972.
38. Williams, J. L., J. H. Chen, and D. M. Belloli. Strain fields on cell stressing devices employing clamped circular elastic diaphrams as substrates. J. Biomech. Eng. 114:377-384, 1992.
39. Winston, F. K., E. J. Macarak, S. F. Gorfien, and L. E. Thibault. A system to reproduce and quantify the biomechanical environment of the cell. J. Appl. Physiol. 67:397-405, 1989.