Mini symposium: Spermatid injections for male infertility: Micro- and macro-consequences of ooplasmic injections of early haploid male gametes

Human Reproduction Update

Volumn 4, Issue 3, 1998, Pages 197-212

  Sofikitis, Nikolaos ^a   Miyagawa, Ikuo ^a   Yamamoto, Yasuhisa ^a   Loutradis, Dimitrios ^b   Mantzavinos, Themis ^b   Tarlatzis, Vasilios ^c  

^a TOTTORI UNIVERSITY   (Japan)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

ROSNI; Spermatid; Spermatogenesis

Indexed keywords

ANIMAL CELL; AZOOSPERMIA; CELL ISOLATION; CELL NUCLEUS; CELL SELECTION; CELL SHAPE; CONFERENCE PAPER; EMBRYO; FEMALE; GENETICS; GENOME IMPRINTING; HAMSTER; HUMAN; HUMAN CELL; INTRACYTOPLASMIC SPERM INJECTION; MALE; MEDICAL ETHICS; NONHUMAN; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROGENY; QUALITY CONTROL; RABBIT; SAFETY; SPERMATID; SPERMATOGENESIS; ZYGOTE; ANIMAL; CELL NUCLEUS TRANSPLANTATION; CYTOPLASM; FERTILIZATION IN VITRO; HAPLOIDY; METHODOLOGY; MICROINJECTION; OLIGOSPERMIA; OOCYTE; REVIEW; ULTRASTRUCTURE;

ANIMALS; CYTOPLASM; FEMALE; FERTILIZATION IN VITRO; HAPLOIDY; HUMANS; MALE; MICROINJECTIONS; NUCLEAR TRANSFER TECHNIQUES; OLIGOSPERMIA; OOCYTES; SPERMATIDS; SPERMATOGENESIS; ZYGOTE;

EID: 0032063028     PISSN: 13554786     EISSN: None     Source Type: Journal    
DOI: 10.1093/humupd/4.3.197     Document Type: Conference Paper

References (87)

1. Akmal, K.A., Dufour, J.M. and Kim, K. (1997) Retinoic acid receptor α gene expression in the rat testis: potential role during the prophase of meiosis and in the transition from round to elongating spermatids. Biol. Reprod., 56, 549-556.
2. Amer, M., Soliman, E., El-Sadek, M. et al. (1997) Is complete spermiogenesis failure a good indication for spermatid conception? Lancet, 350, 116.
3. Anderson, D.M., Lyman, S.D., Baird, A. et al. (1990) Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms. Cells, 63, 235-243.
4. Angelopoulos, T., Krey, L., McCullough, A. et al. (1997) A single and objective approach to identifying human round spermatids. Hum. Reprod., 12, 2208-2216.
5. Antinori, S.,Versaci, C.,Dani, G. et al. (1997a) Fertilization with human testicular spermatids: four successful pregnancies. Hum. Reprod., 12, 285-291.
6. Antinori, S.,Versaci, C., Dani, G. et al. (1997b) Successful fertilization and pregnancy after injections of frozen-thawed round spermatids into human oocytes. Hum. Reprod., 12, 554-556.
7. Araki,Y., Motoyama, M., Yoshida, A. et al. (1997) Intracytoplasmic injection of late spermatids: a successful procedure in achieving childbirth for couples in which the male partner suffers from azoospermia due to deficient spermatogenesis. Fertil. Steril., 22, 559-561.
8. Baschat, A., Schwinger, E. and Diedrich, K. (1996) Assisted reproductive techniques - are we avoiding the genetic issues? Hum. Reprod., 11, 330-333.
9. Bates, G.W. (1987) Electrofusion: principles and applications. In Sowers, A.E. (ed.), Cell Fusion. Plenum Press, New York, pp. 367-395.
10. Chai, N., Phyllips, A., Fernandez, A. et al. (1997) A putative human male infertilitygene DAZLA: genomic structure and methylation status. Mol. Hum. Reprod., 3, 705-708.
11. Chabot, B.,Stephenson, D.A., Chapman, V.M. et al. (1988) The protooncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature, 335, 88-89.
12. Chen, S., Ho, H., Chen, H. et al. (1996) Fertilization and embryo cleavage after intracytoplasmic spermatid injection in an obstructive azoospermic patient with defective spermiogenesis. Fertil. Steril., 66, 157-60.
13. Dozortsev, D., Rybouchkin, A., De Sutter, P. et al. (1995) Human oocyte activation following intracytoplasmic sperm injection: the role of the sperm cell. Hum. Reprod., 10, 403-407.
14. De Kretser, D.M. and Kerr, J.M. (1988) The cytology of the testis. In Knobil, E. and Neil, J. (eds), The Physiology of Reproduction. Raven Press, New York, pp. 837-866.
15. Edwards, R.G., Tarin, J.J., Dean, N.N. et al. (1994) Are spermatid injections into human oocytes now mandatory? Hum. Reprod., 9, 2217-2219.
16. Fawcett, D.M., Anderson, W.A. and Phillips, D.M. (1971) Morphogenetic factors influencing the shape of the sperm head. Dev. Biol., 26, 220-251.
17. Fishel, S., Green, S., Bishop, M. et al. (1995) Pregnancy after intracytoplasmic injection of spermatid. Lancet, 345, 1641-1642.
18. Fishel, S., Aslam, I. and Tesarik, J. (1996) Spermatid conception: a stage too early, or a time too soon? Hum. Reprod., 11, 1371-1375.
19. Fishel, S., Green, S., Hunter, A. et al. (1997) Human fertilization with round and elongated spermatids. Hum. Reprod., 12, 336-340.
20. Gerton, G.L. and Millette, C.F. (1984) Generation of flagella by cultured mouse spermatids. J. Cell Biol., 98, 619-628.
21. Goto, K., Kinoshita, A., Nakanishi, Y. et al. (1996) Blastocyst formation following intracytoplasmic injection of in-vitro derived spermatids into bovine oocytes. Hum. Reprod., 11, 824-829.
22. Gritch, H., Bruning, C. and Robles, M. (1997) Long term spermatogenic cell culture. J. Urol., 157 (Suppl.), abstract 654, p. 169.
23. Hannay, T. (1995) New Japanese IVF method finally made available in Japan. Nature Med., 1, 289-290.
24. Janny, L. and Ménézo, Y. (1994) Evidence for strong paternal effect on human preimplantation embryo development and blastocyst formation. Mol. Reprod. Dev., 38, 36-42.
25. Kimura, Y. and Yanagimachi, R. (1995a) Mouse oocytes injected with testicular spermatozoa or round spermatids can develop into normal offspring. Development, 121, 2397-2405.
26. Kimura, Y. and Yanagimachi, R. (1995b) Development of normal mice from oocytes injected with secondary spermatocyte nuclei. Biol. Reprod., 53, 855-862.
27. Mansour, R.T., Aboulghar, M.A., Serour, K. et al. (1996a) Pregnancy and delivery after intracytoplasmic injection of spermatids into human oocytes. Middle East Fertil. Soc., 1, 223-225.
28. Mansour, R.T., Aboulghar, M.A., Serour, G. et al. (1996b) Successful intracytoplasmic sperm injection without performing cytoplasmic aspiration. Fertil. Steril., 66, 256-159.
29. Mazia, D. (1984) Centrosomes and mitotic poles. Cell Res., 153, 1-23.
30. Mendoza, C. and Tesarik, J. (1996) The occurrence and identification of round spermatids in the ejaculate of men with non-obstructive azoospermia. Fertil. Steril., 66, 826-829.
31. Mendoza, C., Benkhalifa, M., Cohen-Bacrie, P. et al. (1996) Combined use of proacrosin immunochemistry and autosomal DNA in situ hybridization for evaluation of human ejaculated germ cells. Zygote, 4, 279-283.
32. Meng, L. and Wolf, D.P. (1997) Sperm induced oocyte activation in the rhesus monkey: nuclear and cytoplasmic changes following intracytoplasmic sperm injection. Hum. Reprod., 12, 1062-1068.
33. Nagy, Z., Liu, J., Joris, H. et al. (1994) Time course of oocyte activation, pronucleus formation, and cleavage in human oocytes fertilized by intracytoplasmic sperm injection. Hum. Reprod., 9, 1743-1748.
34. Nakamura, M., Romrell, L.J. and Hall, P. (1978) The effects of glucose and temperature on protein biosynthesis by immature (round) spermatids from rat testis. J. Cell Biol., 79, 1-9.
35. Navara, C., First, N. and Schatten, G. (1994) Microtubule organization in the cow during fertilization, polyspermy, parthenogenesis, and nuclear transfer: the role of the sperm transfer. Dev. Biol., 162, 29-40.
36. O'Donnell, L., McLachlan, R., Wreford, N. et al. (1996) Testosterone withdrawal promotes stage-specific detachment of round spermatids from the rat seminiferous epithelium. Biol. Reprod., 55, 895-901.
37. Ogura, A. and Yanagimachi, R. (1993) Round spermatid nuclei injected into hamster oocytes form pronuclei and participate in syngamy. Biol. Reprod., 48, 219-225.
38. Ogura, A., Yanagimachi, R. and Usui, N. (1993) Behavior of hamster and mouse round spermatid nuclei incorporated into mature oocytes by electrofusion. Zygote, 1, 1-8.
39. Ogura, A., Matsuda, J. and Yanagimachi, R. (1994) Birth of normal young after electrofusion of mouse oocytes with round spermatids. Proc. Natl. Acad. Sci. USA, 91, 7460-7462.
40. Ono, K., Sofikitis, N., Miyagawa, I. (1996) Fertilization of rabbit oocytes with nuclei extracted from thawed round spermatids. Jpn. J. Urol., 87 (Suppl. 2), 393.
41. Ono, K. Miyagawa, I. Sofikitis, N. et al. (1997) Defects in genetic and epigenetic contributions of the male gamete to zygote affect early embryonic development and compromise embryonic capacity for implantation. Fertil. Steril., 68 (Suppl.), abstract P-152, pp. S165-166.
42. Ozil, J.P. (1990) The parthenogenetic development of rabbit oocytes after pulsatile electrical stimulation. Development, 109, 117-27.
43. Palermo, G., Joris, H., Devroy, P. et al. (1992) Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet, 340, 17-18.
44. Palermo, G., Munné, S. and Cohen, J. (1994) The human zygote inherits its mitotic potential from the male gamete. Hum. Reprod., 9, 1220-1227.
45. Parrington, J., Swann, K., Shevchenko, V. et al. (1996) Calcium oscillations in mammalian eggs triggered by a soluble protein. Nature, 379, 364-368.
46. Perreault, S. and Zirkin, B.R. (1982) Sperm nuclear decondensation in mammals: role of sperm associated proteinase in vivo. J. Exp. Zool., 224, 253-257.
47. Perreault, S., Naish, S. and Zirkin, B.R. (1987) The timing of hamster sperm nuclear decondensation and male pronucleus formation is related to sperm nuclear disulfide bond content. Biol. Reprod., 36, 239-244.
48. Rajfer, J., Turner, T.T., Rivera, F. et al. (1987) Inhibition of testicular testosterone synthesis following experimental varicocele in rats. Biol. Reprod., 36, 933-937.
49. Russell, L.D. and Brinster, R.L. (1996) Ultrastructural observations of spermatogenesis following transplantation of rat testis cells into mouse seminiferous tubules. J. Androl., 17, 615-626.
50. Russell, L.D., Franca, L.R. and Brinster, R.L. (1996) Ultrastructural observations of spermatogenesis in mice resulting from transplantation of mouse spermatogonia. J. Androl., 17, 603-614.
51. Sasagawa, I. and Yanagimachi, R. (1997) Spermatids from mice after cryptorchid and reversal operations can initiate normal embryo development. J. Androl., 18, 203-209.
52. Sathananthan, A.H., Kola, I., Osborne, J. et al. (1991) Centrioles in the beginning of human development. Proc. Natl. Acad. Sci. USA, 88, 4806-4810.
53. Schatten, G. (1994) The centrosome and its mode of inheritance: the reduction of centrosome during gametogenesis and its restoration during fertilization. Dev. Biol., 165, 299-335.
54. Schatten, G., Schatten, H., Mazia, D. et al. (1986) Behaviors of centrosomes during fertilization and cell division in mouse oocytes and sea urchin eggs. Proc. Natl. Acad. Sci. USA, 85, 105-109.
55. Silber, S.J. (1996) Sertoli cell-only syndrome. Hum. Reprod., 11, 229-33.
56. Silber, S.J., Nagy, Z., Liu, J. et al. (1995a) The use of testicular and epididymal spermatozoa for intracytoplasmic sperm injections: the genetic implications for male infertility. Hum. Reprod., 10, 2031-2043.
57. Silber, S.J., Van Steirteghem, A.C. and Devroy, P. (1995b) Sertoli cell only revisited. Hum. Reprod., 10, 1031-1032.
58. Silber, S.J., Nagy, Z., Devroy, P. et al. (1997) Distribution of spermatogenesis in the testicles of azoospermic men: the presence or absence of spermatids in the testes of men with germinal failure. Hum. Reprod., 12, 2422-2428.
59. Simerly, C., Wu, G., Zoran, S. et al. (1995) The paternal inheritance of the centrosome, the cell's microtubule-organizing center, in humans and the implications for infertility. Nature Med., 11, 47-52.
60. Sofikitis, N.V., Miyagawa, I., Agapitos, E. et al. (1994a) Reproductive capacity of the nucleus of the male gamete after completion of meiosis. J. Assist. Reprod. Genet., 11, 335-341.
61. Sofikitis, N., Miyagawa, I., Zavos, P.M. et al. (1994b) Confocal scanning laser microscopy of morphometric human sperm parameters: correlation with acrosin profiles and fertilizing capacity. Fertil. Steril., 62, 376-386.
62. Sofikitis, N., Miyagawa, I., Sharlip, I. et al. (1995a) Human pregnancies achieved by intra-ooplasmic injections of round spermatid nuclei isolated from testicular tissue of azoospermic men. Presented at the American Urological Association 90th Annual Meeting in Las Vegas, April 23-28, 1995. J. Urol., 153 (Suppl.), 258A.
63. Sofikitis, N., Toda, T., Miyagawa, I. et al. (1995b) Application of ooplasmic round spermatid nuclear injections for the treatment of azoospermic men in USA. Fertil. Steril., 64 (Suppl.), S88-S89.
64. Sofikitis, N.V., Toda, T., Miyagawa, I. et al. (1996a) Beneficial effects of electrical stimulation before round spermatid nuclei injections into rabbit oocytes on fertilization and subsequent embryonic development. Fertil. Steril., 65, 176-185.
65. Sofikitis, N. V., Miyagawa, I., Incze, P. et al. (1996b) Detrimental effect of left varicocele on the reproductive capacity of the early haploid male gamete. J. Urol., 156, 267-270.
66. Sofikitis, N.V., Yamamoto, Y. and Miyagawa, I. (1997a) The azoospermic father: Fact or fiction? the reproductive potential of the early haploid male gamete. In Waites, G.M.H., Frick, J. and Baker, J.W.H. (eds), Current Advances in Andrology. Monduzzi Editore, Bologna, pp. 189-195.
67. Sofikitis, N.V., Mantzavinos, T., Loutradis, D. et al. (1997b) Treatment of male infertility caused by spermatogenic arrest at the primary spermatocyte stage with ooplasmic injections of round spermatids or secondary spermatocytes isolated from foci of early haploid male gametes. Presented at the 13th Annual Meeting of The European Society of Human Reproduction and Embryology in Edinburgh, June 22-25, 1997. Hum. Reprod., 12 (Suppl.), 81-82.
68. Sofikitis, N.V., Kanakas, N., Mantzavinos, T. et al. (1997c) Deficiency in the oocyte-activating substance in spermatozoa: a cause of ICSI failure. Presented at the 13th Annual Meeting of The European Society of Human Reproduction and Embryology in Edinburgh, June 22-25, 1997. Hum. Reprod., 12 (Suppl.), 81.
69. Sofikitis, N., Yamamoto, Y. and Miyagawa, I. (1997d) The early haploid male gamete develops a capacity for fertilization after the coalescence of the proacrosomal granules. Hum. Reprod., 12, 2713-2719.
70. Sofikitis, N., Yamamoto, Y., Miyagawa, I. et al. (1998a) Ooplasmic elongating spermatid injections for the treatment of non-obstructive azoospermia. Hum. Reprod. 13, 709-714.
71. Sofikitis, N., Mantzavinos, T., Loutradis, D. et al. (1998b) Delivery of a healthy male after ooplasmic injections of secondary spermatocytes. To be presented at The 23rd Annual Meeting of The American Society of Andrology at Long Beach, CA, USA, March 27-29, 1998. J. Androl., 19 (Suppl. 1), 57 (abstract).
72. Sousa, M., Barros, A. and Tesarik, J. (1996) Calcium responses of human oocytes after intracytoplasmic injection of leukocytes, spermatocytes, and round spermatids. Mol. Hum. Reprod., 2, 853-857.
73. Swann, K. (1990) A cytosolic sperm factor stimulates repetitive calcium increases and mimics fertilization in hamster eggs. Development, 110, 1295-302.
74. Tanaka, A., Nagayoshi, M., Awata, S. et al. (1996) Clinical evaluation of round spermatid injection into human oocytes. Fertil. Steril., 66 (Suppl.), abstract P 12, p. S99.
75. Tanaka, A., Nagayoshi, M. and Sofikitis, N. (1997) Conclusions from transplantation of human or hamster spermatogonia/primary spermatocytes to rat or mouse testis. Fertil. Steril., 68 (Suppl.), abstract O-122, p. S61.
76. Taylor, C.T., Lawrence, Y.M., Kingsland, C.R. et al. (1993) Oscillations in intracellular free calcium induced by spermatozoa in human oocytes at fertilization. Hum. Reprod., 8, 2174-2179.
77. Tesarik, J., Sousa, M. and Testart, J. (1994) Human oocyte activation after intracytoplasmic sperm injection. Hum. Reprod., 9, 511-518.
78. Tesarik, J., Mendoza, C. and Testart, J. (1995) Viable embryos from injection of round spermatids into oocyte. N. Engl. J. Med., 333, 525.
79. Tesarik, J., Rolet, F., Brami, C. et al. (1996) Spermatid injections into oocytes. II. Clinical application in the treatment of infertility due to non-obstructive azoospermia. Hum. Reprod., 11, 780-783.
80. Tycko, B. (1997) Post-graduate course program of The American Society of Andrology, 22nd Annual Meeting, Baltimore, Maryland, February 22-25, pp. 83-106.
81. Vanderzwalmen, P., Lejeune, B., Nijs, M. et al. (1995) Fertilization of an oocyte microinseminated with a spermatid in an in-vitro fertilization program. Hum. Reprod., 10, 502-503.
82. Vanderzwalmen, P., Zech, H., Birkenfeld, ? et al. (1997) Intracytoplasmic injection of spermatids retrieved from testicular tissue: influence of testicular pathology, type of selected spermatids and oocyte activation. Hum. Reprod., 12, 1203-1213.
83. Vitullo, A.D. and Ozil, J.P. (1992) Repetive calcium stimuli derive meiotic resumption and pronuclei development during mouse oocyte activation. Dev. Biol., 151, 128-136.
84. Weiss, M., Vigier, M., Hue, D. et al. (1997) Pre- and postmeiotic expression of male germ cell-specific genes throughout 2-week-cocultures of rat germinal and Sertoli cells. Biol. Reprod., 57, 68-76.
85. Werthman, P., Kaboo, R., Peng, S. et al. (1997) Adenoviral mediated gene transfer to murine testis in vivo. J. Urol., 157 (Suppl. 1), abstract 653, p. 169.
86. Yamamoto, Y., Sofikitis, N. and Miyagawa, I. (1997) Round spermatid nuclear injections (ROSNI) versus intact round spermatid injections (ROSI) into the ooplasm. Int. J. Androl., 20 (Suppl. 1), p. a-133.
87. Yamanaka, K., Sofikitis, N., Miyagawa, I. et al. (1997) Ooplasmic round spermatid nuclear injections as an experimental treatment of non-obstructive azoospermia. J. Assist. Reprod. Genet., 14, 55-62.