Glutathione and glutathione S-transferase in blood and in leucocytes: relationship with cholesterolemia in healthy volunteers;GLUTATHION ET GLUTATHION S-TRANSFERASE SANGUINS ET LEUCOCYTAIRES: RELATION AVEC LA CHOLESTEROLEMIE CHEZ DES VOLONTAIRES SAINS

Annales de Biologie Clinique

Volumn 56, Issue 3, 1998, Pages 321-327

  Gannage Yared M H ^a   Khneisser, I ^a   Salem, N ^a   Gouyette, A ^b   Loiselet, J ^a   Halaby, G ^a   Massade, L ^b  

^a SAINT JOSEPH UNIVERSITY   (Lebanon)

^b INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Body mass index; Cholesterolemia; Glutathione; Glutathione S transferase

Indexed keywords

ESTROGEN; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LOW DENSITY LIPOPROTEIN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGE; ARTICLE; ATHEROGENESIS; BODY MASS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; LEUKOCYTE; LIPID OXIDATION; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; NORMAL HUMAN; SEX DIFFERENCE; SMOKING; SPECTROPHOTOMETRY; BLOOD; CHEMISTRY; GLUCOSE BLOOD LEVEL; MIDDLE AGED; REFERENCE VALUE; SEXUAL DEVELOPMENT;

ADULT; BLOOD GLUCOSE; BODY MASS INDEX; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; FEMALE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; REFERENCE VALUES; SEX CHARACTERISTICS; TRIGLYCERIDES;

EID: 0032061645     PISSN: 00033898     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Akerboom TPM, Sies H. Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Methods Enzymol 1981 ; 77 : 373-82.
2. Armstrong RN. Glutathione S-transferases: reaction mechanism, structure, and function. Chem Res Toxicol 1991 ; 4 : 131-40.
3. Mannervick B. The isoenzymes of glutathione S-transferase. Adv Enzymol 1985 ; 57 : 357-417.
4. Ogura K, Nishiyama T, Okada T, et al. Molecular Cloning and amino acid sequencing of rat liver class theta glutathione S-transferases Yrs-Yrs inactivating reactive sulfate esters of carcinogenic arylmethanols. Biochem Biophys Res Comm 1991 ; 181 : 1294-300.
5. Sinning I, Kleywegt GJ, Cowan SW, et al. Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi Class enzymes. J Mol Biol 1993 ; 232 : 192-212.
6. Pickelt CB, Lu AYH. Glutathione S-transferases: gene structure, regulation and biological function. Annu Rev Biochem 1989 ; 58 : 743-64.
7. Beutler E, Gelbart T. Plasma glulathione in health and in patients with malignant disease. J Lab Clin Med 1985 ; 105 : 581-4.
8. Guengerich FP, Thier R, Persmark M, Taylor JB, Pemble SE, Ketterer B. Conjugation of carcinogens by q class glulathione S-transferase: mechanisms and relevance to variations in human risk. Pharmacogenetics 1995 ; 5 : S103-7.
9. Mistry P, Harrap KR. Historical aspects of glutathione and cancer chemotherapy. Pharmac Ther 1991 ; 49 : 125-32.
10. Hercbergs A, Brok-Simoni F, Holtzman F, Bar-Am J, Leith JT, Brenner HJ. Erythrocyte glutathione and tumour response to chemotherapy. Lancet 1992 ; 339 : 1074-6.
11. Reaven PD, Witztum JL. The role of oxidation of LDL in atherogenesis. The Endocrinologist 1995 ; 5 : 44-54.
12. Regnström J, Nilsson J, Tornvall P, Landou C, Hamsten A. Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet 1992 ; 339 : 1183-6.
13. De Rijke YB, Vogelzang CJM, Van Berkel TJC, et al. Susceptibility to low density lipoproteins to oxidation in coronary bypass patient [Letter]. Lancet 1992 ; 340 : 858-9.
14. Zieden B, Molgaard J, Olsson AG. Low-density lipoprotein oxidation and coronary atherosclerosis [Letter]. Lancet 1992 ; 340 : 727-8.
15. Leake DS. Oxidised low density lipoprotein and atherogenesis. Br Heart J 1993 ; 69 : 476-8.
16. Witztum JL, Steinberg D. Role of oxidized low density lipoprotein in atherogenesis. J Clin Invest 1991 ; 88 : 1785-92.
17. Aviram M. Modified forms of low density lipoprotein and atherosclerosis. Atherosclerosis 1993 ; 98 : 1-9.
18. Darley-Usmar VM, Severn A, O'Leary VJ, Rogers M. Treatment of macrophages with oxidized low-density lipoprotein increases their intracellular glutathione content. Biochem J 1991 ; 278 : 429-34.
19. Gotoh N, Graham A, Niki E, Dartey U. Inhibition of glutathione synthesis increases the toxicity of oxidized low density lipoprotein to human monocytes and macrophages. Biochem J 1993 ; 296 : 151-4.
20. Julius M, Lang CA, Gleiberman L, Harburg E, DiFranceisco W, Schork A. Glutathione and morbidity in a community-based sample of elderly. J Clin Epidemiol 1994 ; 47 : 1021-6.
21. Michelet F, Gueguen R, Leroy P, Wellman M, Nicolas A, Siest G. Blood and plasma glutathione measured in healthy subjects by HPLC: relation to sex, aging, biological variables, and life habits. Clin Chem 1995 ; 41 : 1509-17.
22. Habig WH, Jacoby WB. Assays for differenciation of glutathione S-transférase. Methods Enzymol 1981 ; 77 : 373-84.
23. Hartmann L. Techniques modernes de laboratoires et explorations fonctionnelles. 1971 : 271-3.
24. Cominacini L, Pastorino AM, Garbin U, et al. The susceptibility of low-density lipoprotein to in vitro oxidation is increased in hypercholesterolemic patients. Nutrition 1994 ; 10 : 527-31.
25. Levy A, Brook JG, Dankner G, Ben-Amotz A, Aviram. Enhanced in vitro oxidation of plasma lipoproteins derived from hypercholesterolemic patients. Metabolism 1991 ; 40 : 794-9.
26. Lamb DJ, Wilkins GM, Leake DS. The oxidative modification of low density lipoprotein by human lymphocytes. Atherosclerosis 1992 ; 92 : 187-92.
27. Leake DS, Rankin SM. The oxidative modification of low density lipoproteins by macrophages. Biochem J 1990 ; 270 : 741-8.
28. Denke MA. Hormone replacement therapy : benefit and safety issues. Curr Opin Lipidol 1996 ; 6 : 369-73.
29. Shwaery GT, Vita JA, Keaney JF Jr. Antioxidant protection of LDL by physiological concentrations of 17 beta estradiol. Requirement for estradiol modification. Circulation 1997 ; 95 : 1378-85.
30. Mazière C, Auclair M, Ronveaux MF, Salmon S, Santus R, Mazière JC. Estrogens inhibit copper and cell-mediated modification of low density lipoprotein. Atherosclerosis 1991 ; 89 : 175-82.
31. Ruiz-Larrea MB, Garrido MJ, Lacort M. Estradiol-induced effects on glutathione metabolism in rat hepatocytes. J Biochem (Tokyo) 1993 ; 113 : 563-7.
32. Lang CA, Naryshkin S, Schneider DL, Mills BJ, Lindeman RD. Low blood glutathione levels in healthy aging adults. J Lab Clin Med 1992 ; 120 : 720-5.
33. Siekmeier R, Wülfroth P, Wieland H, Grob W, Marz W. Low-density lipoprotein susceptibility to in vitro oxidation in healthy smokers and nonsmokers. Clin Chem 1996 ; 42 : 524-30.
34. Reaven GM, Chen Y-DY, Jeppesen J, Maheux P, Krauss RM. Insulin resistance and hyperinsulinaemia in individuals with small, dense, low density lipoprotein particles. J Clin Invest 1993 ; 92 : 141-6.
35. de Uraaf J, Hak-Lominers HLM, Hectors MPC, Demacker PNM, Hendriks JCM, Stalenhoef AFH. Enhanced susceptibility to in vitro oxidation of the dense low density lipoprotein subfraction in health subjects. Arterioscler Thromb 1991 ; 11 : 298-306.