Structural impairments in optic nerve of diabetic rats ameliorated with the aldose reductase inhibitor

Experimental Eye Research

Volumn 66, Issue 4, 1998, Pages 397-401

  Ino Ue, Masanori ^a   Yokogawa, Hiromi ^a   Yamamoto, Misao ^a   Naka, Hiroaki ^b   Kuriyama, Hiroshi ^b  

^a KOBE UNIVERSITY   (Japan)

^b SENJU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Aldose reductase inhibitor; Diabetes mellitus; Myelinated fiber caliber; Optic nerve

Indexed keywords

ALDOSE REDUCTASE INHIBITOR; GLUCOSE; SG 210; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; MYELINATED NERVE; NONHUMAN; OPTIC NERVE DISEASE; OPTIC NERVE FIBER; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; WEIGHT REDUCTION;

EID: 0032055846     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1997.0426     Document Type: Article

References (33)

1. Alberghina M. Metabolic correlates and axonal transport in nerves during experimental diabetes. Metab. Pediat. Sys. Ophthalmol. 9:1986;71-73.
2. Apaydin C., Oguz Y., Agar A., Yargicoglu P., Remir N., Aksu G. Visual evoked potentials and optic nerve histopathology in normal and diabetic rats and effect of ginkgo biloba extract. Acta Ophthalmol. 71:1993;623-628.
3. Barnett A. H. Origin of the microangiopathic changes in diabetes. Eye. 7:1993;218-222.
4. Berninger T. A., Arden G. B. The pattern electroretinogram. Eye. 2:1988;(Suppl), 257-83.
5. Boschi D., Frosini M. C., Mencucei R., Sodi A. The influence of early diabetes on the pattern electroretinogram. Doc Ophthalmol. 71:1989;369-373.
6. Boycott B. B., Wassle H. The morphological type of ganglion cells of the domestic cat's retina. J. Physiol. (London). 240:1974;397-419.
7. Bresnick G. Diabetic retinopathy viewed as a neurosensory disorder. Arch. Ophthalmol. 104:1986;989-990.
8. Charkrabarti S., Slima A. A. F., Nakajima T., Yagihashi S., Greene D. A. Aldose reductase in the BD rat: isolation, immunological identification and localization in the retina and peripheral nerve. Diabetologia. 30:1987;244-251.
9. Chihara E. Impairment of protein synthesis in the retinal tissue in diabetic rabbits: secondary reduction of fast axonal transport. J. Neurochem. 37:1981;247-250.
10. Chihara E., Sakugawa M., Entani S. Reduced protein synthesis in diabetic retina and secondary reduction of slow axonal transport. Brain Research. 250:1982;363-366.
11. Comi G., Martinelli V., Galardi G., Medaglini S., Beccaria L., Meschi F., Rosti L., Bressani N., Chiumello G. Evaluation of central nerve conduction by visual evoked potentials in insulin-dependent diabetic children. Metabolic and clinical correlation. Acta. Diabetol. Lata. 24:1987;157-162.
12. Della Sala S., Bertoni G., Somazzi L., Stubbe F., Willkins A. J. Impaired contrast sensitivity in diabetic patients with and without retinopathy: A new technique for rapid assessment. Br. J. Ophthalmol. 69:1985;136-142.
13. DiLeo M. A. S., Falsini B., Caputo S., Ghirlanda G., Porciatli V., Greco A. V. Spatial frequency-selective losses with pattern electroretinogram type I (insulin-dependent) diabetic patients without retinopathy. Diabetologia. 33:1990;726-730.
14. Dyck P. J., Lanbert E. H., Windebank A. J., Lais A. C., Sparks M. F., Karnes J., Sherman W. R., Hallcher L. M., Low P. A., Service F. J. Acute hyperosmolar hyperglycemia causes axonal shrinkage and reduced nerve conduction velocity. Exp. Neurol. 71:1981;507-514.
15. Ghafour I. M., Foulds W. S., Fllan D., McClure F. Contrast sensitivity in diabetic subjects with and without retinopathy. Br. J. Ophthalmol. 66:1982;492-495.
16. Giarelli L., Grandi G., Delendi M., Falconieri G. Optic nerve in diabetes mellitus: A case control study. Metab. Pediatric. Sys. Ophthalmol. 9:1986;71-73.
17. Greene D. A., Latlimer S. A., Sima A. A. F. Sorbitol, phosphoinositides, and sodium-potassium-ATPase in the pathogenesis of diabetic complications. N. Engl. J. Med. 316:1987;599-606.
18. Jakobsen J. Axonal dwindling in early experimental diabetes: I. A study of cross sectioned nerves. Diabetologia. 12:1976;539-546.
19. Martinelli V., Filippi M., Meschi F., Pozza G., Canal N., Comi G. C. Electrophysiological study of optic pathways in insulin dependent diabetes mellitus. Clin. Vis. Sci. 6:1991;437-443.
20. Mayer J. H., Tomlinson D. R. Prevention of defects of axonal transport and nerve conduction velocity by oral administration of myo-inositol or an aldose reductase inhibitor in streptozotocin-diabetic rats. Diabetologia. 25:1983;433-438.
21. Medori R., Autilio-Gambetti L., Monaco S., Gambetti P. Experimental diabetic neuropathy: Impairment of slow transport with changes in axon cross-sectional area. Proc. Natl. Acad. Sci. 82:1985;7716-7720.
22. Prager T. C., Garcia C. A., Mincher G. A., Mishra J., Chu H. The pattern electroretinogram in diabetes. Am. J. Ophthalmol. 109:1990;279-284.
23. Puvanendran K., Devathasan G., Wong P. K. Visual evoked responses in diabetes. J. Neurol. Neurosurg. Psychiat. 46:1983;643-647.
24. Robinson W. G. Jr, Laver N. M., Lou M. F. The role of aldose reductase in diabetic retinopathy: Prevention and intervention studies. Progress in retinal and eye research. 1995;Pergamon. p. 593-640.
25. Scott A. C. The electrophysics of a nerve fiber. Rev. Mod. Phys. 47:1975;487-533.
26. Sharma A. K., Bajada S., Thomas P. K. Influence of streptozotocin-induced diabetes on myelinated nerve fiber maturation and on body growth in the rat. Acta. Neuropathol. 53:1981;257-265.
27. Sokol S., Moskowitz A., Skarf B., Evans R., Molitch M., and Senior B. Contrast sensitivity in diabetics with and without background retinopathy. Arch. Ophthalmol. 103:1985;51-54.
28. Trick G. L., Burde R. M., Gordon M. D., Kilo C., Santiago J. V. Retinocortical conduction time in diabetics with abnormal pattern reversal electroretinograms and visual evoked potentials. Doc. Ophthalmol. 70:1988;19-28.
29. Yamazaki H., Adachi-Usami A., Chiba J. Contrast thresholds of diabetic patients determined by VECP and psychophysical measurements. Acta. Ophthalmol. 60:1982;368-392.
30. Yagihashi S., Kamijyo M., Watanabe K. Reduced myelinated fiber size correlates with loss of axonal neurofilaments in peripheral nerve of chronically streptozotocin diabetic rats. Am. J. Pathol. 136:1990a;1365-1373.
31. Yagihashi S., Kamijo M., Ido Y., Mirrlees D. J. Effects of long-term aldose reductase inhibition on development of experimental diabetic neuropathy. Ultrastructural and morphometic studies of sural nerve in streptozocin-induced diabetic rats. Diabetes. 39:1990b;690-696.
32. Yagihashi S., Kamijo M., Baba M., Yagihashi U., Nagai K. Effect of Aminoguanidine on functional and structural abnormalities in peripheral nerve of STZ-induced diabetic rats. Diabetes. 41:1992c;47-52.
33. Yaltkaya K., Balkan S., Baysal A. I. Visual evoked potentials in diabetes mellitus. Acta. Neurol. Scand. 77:1988;239-241.