The organization of the cortical motor system: New concepts

Electroencephalography and Clinical Neurophysiology

Volumn 106, Issue 4, 1998, Pages 283-296

  Rizzolatti, G ^a   Luppino, G ^a   Matelli, M ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Motor cortex; Parietal lobe; Parieto frontal connections; Premotor areas

Indexed keywords

FRONTAL CORTEX; FUNCTIONAL ANATOMY; MOTOR CORTEX; NERVE PROJECTION; PARIETAL LOBE; PRIORITY JOURNAL; REVIEW; SENSORIMOTOR CORTEX;

EID: 0032055592     PISSN: 00134694     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0013-4694(98)00022-4     Document Type: Article

References (108)

1. Andersen, R.A., Asanuma, C., Essick, G. and Siegel, R.M. Corticocortical connections of anatomically and physiologically defined subdivisions within the inferior parietal lobule. J. Comp. Neurol., 1990, 296: 65-113.
2. Barbas, H. and Pandya, D.N. Architecture and frontal cortical connections of the premotor cortex (area 6) in the rhesus monkey. J. Comp. Neurol., 1987,256: 211-228.
3. Boussaoud, D., Ungerleider, L. and Desimone, R. Pathways for motion analysis: cortical connections of the medial superior temporal and fundus of the superior temporal visual areas in the macaque. J. Comp. Neurol., 1990, 296: 462-495.
4. Bremmer, F., Duhamel, J.-R. and Ben Hamed, S. Non-retinocentric coding of visual space in the macaque ventral intraparietal area (VIP). Soc. Neurosci. Abstr., 1996, 22: 666.8.
5. Bremmer, F., Duhamel, J.-R., Ben Hamed, S. and Graf, W. The representation of movement in near extra-personal space in the macaque ventral intraparietal area (VIP). In: P. Thier and H.O. Karnath (Eds.), Parietal Lobe Contributions to Orientation in 3D Space. Springer, Heidelberg, 1997, pp. 255-270.
6. Brodmann, K. Vergleichende Lokalisationslehre der Groshirnrinde. Barth, Leipzig (Reprinted 1925), 1909, 324 pp.
7. Brace, C.J., Goldberg, M.E., Bushnell, C. and Stanton, G.B. Primate frontal eye fields. II. Physiological and anatomical correlates of electrically evoked movements. J. Neurophysiol., 1985, 54: 714-734.
8. Caminiti, R., Ferraina, S. and Johnson, P.B. The sources of visual information to the primate frontal lobe: a novel role for the superior parietal lobule. Cereb. Cortex, 1996, 6: 319-328.
9. Cavada, C. and Goldman-Rakic, P.S. Posterior parietal cortex in rhesus monkey: I. Parcellation of areas based on distinctive limbic and sensory corticocortical connections. J. Comp. Neurol., 1989, 287: 393-421.
10. Colby, C.L., Gattass, R., Oison, C.R. and Gross, G.G. Topographical organization of cortical afférents to extrastriate visual area PO in the macaque: a dual tracer study. J. Comp. Neurol., 1988, 269: 392-413.
11. Colby, C.L. and Duhamel, J.-R. Heterogeneity of extrastriate visual areas and multiple parietal areas in the macaque monkeys. Neuropsychologia, 1991,29:517-537.
12. Colby, C.L., Duhamel, J.-R. and Goldberg, M.E. Ventral intraparietal area of the macaque: anatomic location and visual response properties. J. Neurophysiol., 1993, 69: 902-914.
13. Deiber, M.-P., Passingham, R.E., Colebatch, J.G., Fristen, K.J., Nixon, P.D. and Frackowiak, R.S.J. Cortical areas and the selection of movement: a study with positron emission tomography. Exp. Brain Res., 1991, 84: 393-402.
14. De Renzi, E. Disorders of Space Exploration and Cognition. Wiley, New York, 1982.
15. di Pellegrino, G. and Wise, S.P. A neurophysiological comparison of three distinct regions of the primate frontal lobe. Brain, 1991, 114: 951-978.
16. Dum, R.P. and Strick, P.L. The origin of corticospinal projections from the premotor areas in the frontal lobe. J. Neurosci., 199la, 11: 667-689.
17. Dum, R.P. and Strick, P.L. Premotor areas: nodal points for parallel efferent systems involved in the central control of movement. In: D.R. Humphrey and H.-J. Freund (Eds.), Motor Control: Concepts and Issues. Dahlem Workshop Reports. Wiley, Chichester, 1991b, pp. 383-397.
18. Fadiga, L., Fogassi, L., Pavesi, G. and Rizzolatti, G. Motor facilitation during action observation: a magnetic stimulation study. J. Neurophysiol., 1995, 73: 2608-2611.
19. Ferraina, S., Garasto, M.R., Battaglia-Mayer, A., Ferraresi, P., Johnson, P.B., Lacquaniti, F. and Caminiti, R. Visual control of hand-reaching movement: activity in parietal area 7m. Eur. J. Neurosci., 1997a, 9: 1090-1095.
20. Ferraina, S., Johnson, P.B., Garasto, M.R., Battaglia-Mayer, A., Ercolani, L., Bianchi, L., Lacquaniti, F. and Caminiti, R. Combination of hand and gaze signals during reaching: activity in parietal area 7m of the monkey. J. Neurophysiol., 1997b, 77: 1034-1038.
21. Foerster, O. Motorische felder und bahnen. Sensible corticale felder. In: O. Bumke and O. Foerster (Eds.), Handbuck der Neurologie, Vol. 6. Springer, Berlin, 1936, pp. 1-357.
22. Fogassi, L., Gallese, V., Fadiga, L., Luppino, G., Matelli, M. and Rizzolatti, G. Coding of peripersonal space in inferior premotor cortex (area F4). J. Neurophysiol., 1996, 76: 141-157.
23. Freund, H.-J. What is the evidence for multiple motor areas in the human brain? In: D. R. Humphrey and H.-J. Freund (Eds.), Motor Control: Concepts and Issues. Wiley, Chichester, UK, 1991, pp. 399-411.
24. Gallese, V., Murata, A., Kaseda, M., Niki, N. and Sakata, H. Deficit of hand preshaping after muscimol injection in monkey parietal cortex. NeuroReport, 1994, 5: 1525-1529.
25. Gallese, V., Fadiga, L., Fogassi, L. and Rizzolatti, G. Action recognition in the premotor cortex. Brain, 1996, 119: 593-609.
26. Gallese, V., Fadiga, L., Fogassi, L., Luppino, G. and Murata, A. A parietalfrontal circuit for hand grasping movements in the monkey: evidence from reversible inactivation experiments. In: P. Thier and H.-O. Karnath (Eds.), Parietal Lobe Contributions to Orientation in 3D Space. Springer, Heidelberg, 1997, pp. 255-270.
27. Galletti, C., Fattori, P., Battaglini, P.P., Shipp, S. and Zeki, S. Functional demarcation of a border between areas V6 and V6A in the superior parietal gyrus of the macaque monkey. Eur. J. Neurosci., 1996, 8: 30-52.
28. Galletti, C., Fattori, P., Kutz, D.F. and Battaglini, P.P. Arm movementrelated neurons in visual area V6A of the macaque superior parietal lobule. Eur. J. Neurosci., 1997, 9: 410-413.
29. Gattass, R., Sousa, A.P.B. and Cowey, E. Cortical visual areas of the macaque: possible substrates for pattern recognition mechanisms. In: C. Ghagas, R. Gattass and C.G. Gross (Eds.), Pattern Recognition Mechanisms. Pontifical Academy of Sciences, Vatican City, 1985, pp. 1-20.
30. Gattass, R., Sousa, A.P.B., Mishkin, M. and Ungerleider, L.G. Cortical projections of area V2 in the Macaque. Cereb. Cortex, 1997, 7: 110-129.
31. Gentilucci, M., Fogassi, L., Luppino, G., Matelli, M., Camarda, R. and Rizzolatti, G. Functional organization of inferior area 6 in the macaque monkey: I. Somatotopy and the control of proximal movements. Exp. Brain Res., 1988, 71: 475-490.
32. Geyer, S., Ledberg, A., Schleicher, A., Kinomura, S., Schormann, T., Burgel, U., Klingberg, T., Larsson, J., Zilles, K. and Roland, P.E. Two different areas within the primary motor cortex of man. Nature,1996. 382: 805-807.
33. Godschalk, M., Lemon, R.N., Nijs, H.G.T. and Kuypers, H.G.J.M. Behavior of neurons in monkey peri-arcuate and precentral cortex before and during visually guided arm and hand movements. Exp. Brain Res., 1981, 44: 113-116.
34. Godschalk, M., Mitz, A.R., Vanduin, B. and Vanderburg, H. Somatotopy of monkey premotor cortex examined with microstimulation. Neurosci. Res., 1995, 23: 269-279.
35. Grafton, ST., Fadiga, L., Arbib, M.A. and Rizzolatti, G. Premotor cortex activation during observation and naming familiar tools. Neuroimage,1997. 6: 231-236.
36. Graziano, M.S.A., Yap, G.S. and Gross, C.G. Coding of visual space by premotor neurons. Science, 1994, 266: 1054-1057.
37. Graziano, M.S.A., Hu, X.T. and Gross, C.G. Coding the locations of objects in the dark. Science, 1997, 277: 239-241.
38. Halsband, U. and Passingham, R. The role of premotor and parietal cortex in the direction of action. Brain Res., 1982, 240: 368-372.
39. Halsband, U. and Freund, H.-J. Premotor cortex and conditional motor learning in man. Brain, 1990, 113: 207-222.
40. He, S.Q., Dum, R.P. and Strick, P.L. Topographic organization of corticospinal projections from the frontal lobe: motor areas on the lateral surface of the hemisphere. J. Neurosci., 1993, 13: 952-980.
41. He, S.Q., Dum, R.P. and Strick, P.L. Topographic organization of corticospinal projections from the frontal lobe: motor areas on the medial surface of the hemisphere. J. Neurosci., 1995, 15: 3284-3306.
42. Huerta, M.F. and Kaas, J.H. Supplementary eye field as defined by intracortical microstimulation: connections in Macaques. J. Comp. Neurol., 1990, 293: 299-330.
43. Iriki, A., Tanaka, M. and Iwamura, Y. Coding of modified body schema during tool use by macaque postcentral neurones. NeuroReport, 1996,7:2325-2330.
44. Iwamura, Y. and Tanaka, M. Representation of reaching and grasping in the monkey postcentral gyms. Neurosci. Lett., 1996, 214: 147-150.
45. Jeannerod, M., Arbib, M.A., Rizzolatti, G. and Sakata, H. Grasping objects: the cortical mechanisms of visuomotor transformation. Trends Neurosci., 1995, 18: 314-320.
46. Johnson, P.B., Ferraina, S., Bianchi, L. and Caminiti, R. Cortical networks for visual reaching: physiological and anatomical organization of frontal and parietal lobe arm regions. Cereb. Cortex, 1996, 6: 102-119.
47. Kalaska, J.F., Cohen, D.A.D., Prud'homme, M. and Hyde, M.L. Parietal area 5 neuronal activity encodes movement kinematics, not movement dynamics. Exp. Brain Res., 1990, 80: 351-364.
48. Keizer, K. and Kuypers, H.G.J.M. Distribution of corticospinal neurons with collaterals to the lower brain stem reticular formation in monkey (Macaca fascicularis). Exp. Brain Res., 1989, 74: 311-318.
49. Kurata, K. Distribution of neurons with set- and movement-related activity before hand and foot movements in the prcmotor cortex of rhesus monkey. Exp. Brain Res., 1989. 77: 245-256.
50. Kurata, K. Information processing for motor control in primate premotor cortex. Behav. Brain Res., 1994, 61: 135-142.
51. Lacquaniti, F., Guigon, E., Bianchi, L., Ferraina, S. and Caminiti, R. Representing spatial information for limb movement: role of area 5 in the monkey. Cereb. Cortex, 1995, 5: 391-409.
52. Lu, M.T., Preston, J.B. and Strick, P.L. Interconnections between the prefrontal cortex and the premotor areas in the frontal lobe. J. Comp. Neural., 1994, 341: 375-392.
53. Luppino, G., Matelli, M. and Rizzolatti, G. Cortico-cortical connections of two electrophysiologically identified arm representations in the mesial agranular frontal cortex. Exp. Brain Res., 1990, 82: 214-218.
54. Luppino, G., Matelli, M., Camarda, R., Gallese, V. and Rizzolatti, G. Multiple representations of body movements in mesial area 6 and the adjacent cingulate cortex: an intracortical microstimulation study. J. Comp. Neurol., 1991, 311: 463-482.
55. Luppino, G., Matelli, M., Camarda, R. and Rizzolatti, G. Corticocortical connections of area F3 (SMA-proper) and area F6 (pre-SMA) in the macaque monkey. J. Comp. Neurol., 1993, 338: 114-140.
56. Luppino, G., Matelli, M., Camarda, R. and Rizzolatti, G. Corticospinal projections from mesial frontal and cingulate areas in the monkey. NeuroReport, 1994, 5: 2545-2548.
57. Maier, M.A., Davis, J.N., Armand, J., Kirkwood, P.A., Philbin, N., Ognjenovic, N. and Lemon, R.N. Comparison of cortico-motoneuronal (CM) connections from macaque motor cortex and supplementary motor area. Soc. Neurosci. Abstr., 1997, 23: 502.13.
58. Massion, J. Movement, posture and equilibrium: interaction and coordination. Prog. Neurobiol., 1992, 38: 35-56.
59. Matelli, M., Luppino, G. and Rizzolatti, G. Patterns of cytochrome oxidase activity in the frontal agranular cortex of macaque monkey. Behav. Brain Res., 1985, 18: 125-137.
60. Matelli, M., Luppino, G. and Rizzolatti, G. Architecture of superior and mesial area 6 and of the adjacent cingulate cortex. J. Comp. Neural., 1991,311:445-462.
61. Matelli, M., Rizzolatti, G., Bettinardi, V., Gilardi, M.C., Perani, D., Rizzo, G. and Fazio, F. Activation of precentral and mesial motor areas during the execution of elementary proximal and distal arm movements - a PET study. NeuroReport, 1993, 4: 1295-1298.
62. Matelli, M., Luppino, G., Murata, A. and Sakata, H. Independent anatomical circuits for reaching and grasping linking inferior parietal lobule and inferior area 6 in the monkey. Soc. Neurosci. Abstr. 1994,20:404.4.
63. Matelli, M. and Luppino, G. Thalamic input to mesial and superior area 6 in the macaque monkey. J. Comp. Neurol., 1996, 372: 59-87.
64. Matelli, M., Luppino, G., Govoni, P. and Geyer, S. Anatomical and functional subdivisions of inferior area 6 in macaque monkey. Soc. Neurosci. Abstr., 1996, 22: 796.2.
65. Matelli, M. and Luppino, G. Functional anatomy of human motor cortical areas. In: F. Boiler and J. Grafman (Eds.), Handbook of Neuropsychology, Vol. 11. Elsevier, Amsterdam, 1997, pp. 9-26.
66. Maunsell, J.H.R. and Van Essen, D.C. The connections of the middle temporal visual area (MT) and their relationship to a cortical hierarchy in the macaque monkey. J. Neurosci., 1983, 3: 2563-2586.
67. Milner, A.D. and Goodale, M.A. The Visual Brain in Action. Oxford University Press, Oxford, 1995.
68. Mitz, A.R. and Wise, S.P. The somatotopic organization of the supplementary motor area: intracortical microstimulation mapping. J. Neurosci., 1987, 7: 1010-1021.
69. Mountcastle, V.B., Lynch, J.C.G.A., Sakata, H. and Acuna, C. Posterior parietal association cortex of the monkey: command functions for operations within extrapersonal space. J. Neurophysiol., 1975, 38: 871-908.
70. Murata, A., Fadiga, L., Fogassi, L., Gallese, V., Raos, V. and Rizzolatti, G. Object representation in the ventral premotor cortex (area F5) of the monkey. J. Neurophysiol., 1997, 78: 2226-2230.
71. Murray, E.A. and Coulter, J.D. Supplementary sensory area. In: C.N. Woolsey (Ed.), Cortical Sensory Organization, Vol. 1: Multiple Somatic Areas. Humana, Clifton, NJ, 1981, pp. 167-195.
72. Ono, M., Kubik, S. and Abemathey, C.D. Atlas of the Cerebral Sulci. Thieme, Stuttgart, 1990, 218 pp.
73. Pandya, D.N. and Seltzer, B. Intrinsic connections and architectonics of posterior parietal cortex in the rhesus monkey. J. Comp. Neurol., 1982, 204: 204-210.
74. Passingham, R.E. The Frontal Lobe and Voluntary Action. Oxford Uni-versity Press, Oxford, 1993, 299 pp.
75. Paus, T. Location and function of the human frontal eye-field: a selective review. Neuropsychologia, 1996, 34: 475-483.
76. Penfield, W. and Welch, K. The supplementary motor area of the cerebral cortex. Arch. Neurol. Psychiatry, 1951, 66: 289-317.
77. Petrides, M. Motor conditional associative-learning after selective prefrontal lesions in the monkey. Behav. Brain Res., 1982, 5: 407-413.
78. Petrides, M. Deficits on conditional associative-learning tasks after frontal and temporal lesions in man. Neuropsychologia, 1985, 23: 601-614.
79. Petrides, M. and Pandya, D.N. Comparative architectonic analysis of the human and the macaque frontal cortex. In: F. Boiler and J. Grafman (Eds.), Handbook of Neuropsychology, Vol. 9. Eisevier, Amsterdam, 1994, pp. 17-58.
80. Picard, N. and Strick, P.L. Motor areas of the medial wall: a review of their location and functional activation. Cereb. Cortex, 1996, 6: 342-353.
81. Porter, R. and Lemon, R. Corticospinal Function and Voluntary Movement. Clarendon Press, Oxford, 1993, 427 pp.
82. Preuss, T.M., Stepniewska, I. and Kaas, J.H. Movement representation in the dorsal and ventral premotor areas of owl monkeys: a microstimulation study. J. Comp. Neurol., 1996, 371: 649-675.
83. Rao, S.M., Harrington, D.L., Haaland, K.Y., Bobholz, J.A., Cox, R.W. and Binder, J.R. Distributed neural systems underlying the timing of movements. J. Neurosci., 1997, 17: 5528-5535.
84. Rizzolatti, G., Camarda, R., Fogassi, M., Gentilucci, M., Luppino, G. and Matelli, M. Functional organization of inferior area 6 in the macaque monkey: II. Area F5 and the control of distal movements. Exp. Brain Res., 1988, 71: 491-507.
85. Rizzolatti, G., Gentilucci, M., Camarda, R., Gallese, V., Luppino, G. and Matelli, M. Neurons related to reaching-grasping arm movements in the rostral part of area 6 (area 6a/3). Exp. Brain Res., 1990, 82: 337-350.
86. Rizzolatti, G., Fadiga, L., Gallese, V. and Fogassi, L. Premotor cortex and the recognition of motor actions. Cogn. Brain Res., 1996a, 3: 131-141.
87. Rizzolatti, G., Fadiga, L., Matelli, M., Bettinardi, V., Paulesu, E., Perani, D. and Fazio, F. Localization of grasp representations in humans by PET. 1. Observation versus execution. Exp. Brain Res., 1996b, 111: 246-252.
88. Rizzolatti, G., Luppino, G. and Matelli, M. The classic supplementary motor area is formed by two independent areas. In: H.O. Luders (Ed.), Supplementary Sensorimotor Area, Vol. 70. Lippincott-Raven, Philadelphia, 1996c, pp. 45-56.
89. Rizzolatti, G., Fadiga, L., Fogassi, L. and Gallese, V. The space around us. Science, 1997a, 277: 190-191.
90. Rizzolatti, G., Fogassi, L. and Gallese, V. Parietal cortex: from sight to action. Curr. Opin. Neurobiol., 1997b, 7: 562-567.
91. Rizzolatti, G. and Arbib, M.A. Language within our grasp. Trends Neurosci., 1998, in press.
92. Sakata, H., Takaoka, Y., Kawarasaki, A. and Shibutani, H. Somatosensory properties of neurons in the superior parietal cortex (area 5) of the rhesus monkey. Brain Res., 1973, 64: 85-102.
93. Sakata, H., Taira, M., Murata, A. and Mine, S. Neural mechanisms of visual guidance of hand action in the parietal cortex of the monkey. Cereb. Cortex, 1995, 5: 429-438.
94. Schlag, J. and Schlag-Rey, M. Evidence for a supplementary eye field. J. Neurophysiol., 1987, 57: 179-200.
95. Seltzer, B. and Pandya, D.N. Posterior parietal projections to the intraparietal sulcus of the rhesus monkey. Exp. Brain Res., 1986, 62: 459-469.
96. Suzuki, H. and Azuma, M. Topographic studies on visual neurons in the dorsolateral prefrontal cortex of the monkey. Exp. Brain Res., 1983, 53: 47-58.
97. Taira, M., Mine, S., Georgopulos, A.P., Murata, A. and Sakata, H. Parietal cortex neurons of the monkey related to the visual guidance of hand movement. Exp. Brain Res., 1990, 83: 29-36.
98. Tanji, J. and Shima, K. Role for supplementary motor area cells in planning several movements ahead. Nature, 1994, 371: 413-416.
99. Tanji, J., Shima, K. and Mushiake, H. Multiple cortical motor areas and temporal sequencing of movements. Cogn. Brain Res., 1996, 5: 117122.
100. Tanné, J., Boussaoud, D., Boyerzeller, N. and Rouiller, E.M. Direct visual pathways for reaching movements in the macaque monkey. NeuroReport, 1995, 7: 267-272.
101. Turner, O.A. Growth and development of the cerebral cortical pattern in man. Arch. Neurol. Psychiatry, 1948, 59: 1-12.
102. Ungerleider, L.G. and Desimone, R. Cortical projections of visual area MT in the macaque. J. Comp. Neurol., 1986, 248: 190-222.
103. Vaadia, E., Benson, D.A., Hienz, R.D. and Goldstein, M.H. Unit study of monkey frontal cortex: active localization of auditory and visual stimuli. J. Neurophysiol., 1986, 56: 934-952.
104. Vogt, O. and Vogt, C. Ergebnisse unserer Hirnforschung. J. Psychol. Neurol. 1919, 25: 277-462.
105. Wise, S.P., Alexander, G.E., Altman, J.S., Brooks, V.B., Freund, H.-J., Fromm, C.J., Humphrey, D.R., Sasaki, K., Strick, P.L., Tanji, J., Vogel, S. and Wiesendanger, M. Group report: what are the specific functions of the different motor areas? In: D.R. Humphrey and H.-J. Freund (Eds.), Motor Control: Concepts and Issues. Wiley, Chichester, UK, 1991, pp. 463-485.
106. Wise, S.P., Boussaoud, D., Johnson, P.B. and Caminiti, R. Premotor and parietal cortex: corticocortical connectivity and combinatorial computations. Annu. Rev. Neurosci., 1997, 20: 25-42.
107. Woolsey, C.N., Settlage, P.H., Meyer, D.R., Sencer, W., Pinto Hamuy, T. and Travis, A.M. Patterns of localization in precentral and 'supplementary' motor areas and their relation to the concept of a premotor area. Res. Publ. Assoc. Nerv. Ment. Dis., 1952, 30: 238-264.
108. Zilles, K., Schlaug, G., Matelli, M., Luppino, G., Schleicher, A., Qu, M.S., Dabringhaus, A., Seitz, R. and Roland, P.E. Mapping of human and macaque sensorimotor areas by integrating architectonic, transmitter receptor MRI and PET data. J. Anat., 1995, 187: 515-537.