Dominant-negative effect of the lymphocyte function-associated antigen- 1 β (CD18) cytoplasmic domain on leukocyte adhesion to ICAM-1 and fibronectin

Journal of Immunology

Volumn 160, Issue 7, 1998, Pages 3494-3501

  Rey Ladino, Jose A ^a   Pyszniak, Andrew M ^a   Takei, Fumio ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; FIBRONECTIN RECEPTOR; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ANIMAL CELL; ARTICLE; IMMUNOREGULATION; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD18; ANTIGENS, CD4; B-LYMPHOCYTES; CELL ADHESION; CELL LINE; CYTOPLASM; FIBRONECTINS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MICE; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES;

EID: 0032055216     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Kishimoto, T. K., R. S. Larson, A. L. Corbi, M. L. Dustin, D. E. Staunton, and T. A. Springer. 1989. The leukocyte integrins. Adv. Immunol. 46:149.
2. Springer, T. A. 1990. Adhesion receptors of the immune system. Nature 346:425.
3. Staunton, D. E., S. D. Marlin, C. Stratowa, M. L. Dustin, and T. A. Springer. 1988. Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell 52:925.
4. Staunton, D. E., V. J. Merluzzi, R. Rothlein, R. Barton, S. D. Marlin, and T. A. Springer. 1989. A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses. Cell 56:849.
5. de Fougerolles, A. R., S. A. Stacker, R. Schwarting, and T. A. Springer. 1991. Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1. J. Exp. Med. 174:253.
6. Xu, H., I. L. Tong, A. R. De Fougerolles, and T. A. Springer. 1992. Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA. J. Immunol. 149:2650.
7. Fawcett, J., C. L. L. Holness, L. A. Needham, H. Turley, K. C. Gatter, D. Y. Mason, and D. L. Simmons. 1992. Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes. Nature 360:481.
8. Vazeux, R., P. A. Hoffman, J. K. Tomita, E. S. Dickinson, R. L. Jasman, T. St. John, and W. M. Gallatin. 1992. Cloning and characterization of a new intercellular adhesion molecule ICAM-R. Nature 360:485.
9. Springer, T. A. 1990. Adhesion receptors of the immune system. Nature 346:425.
10. Dustin, M. L., and T. A. Springer. 1989. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341:619.
11. van Kooyk, Y., P. van de Wiel-van Kemenade, P. Weder, T. W. Kuijpers, and C. G. Figdor. 1989. Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes. Nature 342:811.
12. Diamond, M. S., and T. A. Springer. 1994. The dynamic regulation of integrin adhesiveness. Curr. Biol. 4:506.
13. Lub, M., Y. Van Kooyk, S. J. Van Vliet, and C. G. Figdor. 1997. Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1. Mol. Biol. Cell 8:341.
14. Keizer, G. D., W. Visser, M. Vliem, and C. G. Figdor. 1988. A monoclonal antibody (NKI-L16) directed against a unique epitope on the α-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions. J. Immunol. 140:1393.
15. 2+ binding epitope on leukocyte integrin α subunits. EMBO J. 8:3759.
16. Diamond, M. S., and T. A. Springer. 1993. A subpopulation of Mac-1 (CD11/ CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J. Cell Biol. 120:545.
17. Burn, P., A. Kupfer, and S. J. Singer. 1988. Dynamic membrane-cytoskeletal interactions: specific association of integrin and talin arises in vivo after phorbol ester treatment of peripheral blood lymphocytes. Proc. Natl. Acad. Sci. USA 85:497.
18. Kupfer, A., P. Burn, and S. J. Singer. 1990. The PMA-induced specific association of LFA-1 and talin in intact cloned T helper cells. J. Mol. Cell. Immunol. 4:317.
19. + modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion. J. Cell Biol. 124:1061.
20. 2 (LFA-1, CD11a/CD18) cytoplasmic domain/cytoskeleton interaction. J. Exp. Med. 181:315.
21. Hibbs, M. L., H. Xu, S. A. Stacker, and T. A. Springer. 1991. a. Regulation of adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin β subunit. Science 251:1611.
22. Hibbs, M. L., S. Jakes, S. A. Stacker, R. W. Wallace, and T. A. Springer. 1991. b. The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 β subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site. J. Exp. Med. 174:1227.
23. Chen, Y. P., T. E. O'Toole, T. Shipley, J. Forsyth, S. E. LaFlamme, K. M. Yamada, S. J. Shattil, and M. H. Ginsberg. 1994. "Inside-out" signal transduction inhibited by isolated integrin cytoplasmic domains. J. Biol. Chem. 269:18307.
24. O'Toole, T. E., Y. Katagiri, R. J. Faull, K. Peter, R. Tamura, V. Quaranta, J. C. Loftus, S. J. Shattil, and M. H. Ginsberg. 1994. Integrin cytoplasmic domains mediate inside-out signal transduction. J. Cell Biol. 124:1047.
25. 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule. Cell 86:233.
26. 1-integrin-linked protein kinase. Nature 379:91.
27. Pyszniak, A. M., C. A. Welder, and F. Takei. 1994. Cell surface distribution of high-avidity LFA-1 detected by soluble ICAM-1-coated microspheres. J. Immunol. 152:5241.
28. Takei, F. 1983. Two surface antigens expressed on proliferating mouse T lymphocytes defined by rat monoclonal antibodies. J. Immunol. 130:2794.
29. Karasuyama, H., A. Kudo, and F. Melchers. 1990. The proteins encoded by the VpreB and λ 5 pre-B cell-specific genes can associate with each other and with μ heavy chains. J. Exp. Med. 172:969.
30. Food, M. R., S. Rothenberger, R. Gabathuler, I. D. Haidl, G. Reid, and W. A. Jefferies. 1994. Transport and expression in human melanomas of a transferrin-like glycosylphosphatidylinositol-anchored protein. J. Biol. Chem. 269:3034.
31. Welder, C. H., D. H. S. Lee, and F. Takei. 1993. Inhibition of cell adhesion by microspheres coated with recombinant soluble ICAM-1. J. Immunol. 150:2203.
32. Hara, T., and S. M. Fu. 1986. Phosphorylation of a and β subunits of 180/100-kDa polypeptides (LFA-1) and related antigens. Leukocyte Typing II 3:77.
33. Cha-Fen, L., and T. A. Springer. 1977. The α subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1. J. Immunol. 159:268.
34. Pyszniak, A. M., C. Carpenito, and F. Takei. 1997. The role of LFA-1 (CD11a/ CD18) cytoplasmic domains in binding to intercellular adhesion molecule-1 (CD54) and in postreceptor cell spreading. Exp. Cell Res. 233:78.
35. Noto, K., K. Kato, K. Okumura, and H. Yahita. 1995. Identification and functional characterization of mouse CD29 with a mAb. Int. Immunol. 7:835.
36. Pavalko, F. M., and S. M. LaRoche. 1993. Activation of human neutrophils induces an interaction between the integrin β2-subunit (CD18) and the actin binding protein α-actinin. J. Immunol 151:3795.
37. Sharma, C. P., R. M. Ezzell, and M. A. Arnaout. 1995. Direct interaction of filamin (ABP-280) with the β2-integrin subunit CD18. J. Immunol. 154:3461.
38. Diaz-Gonzalez, F., J. Forsyth, B. Steiner, and M. H. Ginsberg. 1996. Trans-dominant inhibition of integrin function. Mol. Biol. Cell 7:1939.
39. Ruegg, C., A. A. Postigo, E. E. Sikorski, E. C. Butcher, R. Pytela, and D. J. Erle. 1992. Role of integrin α4 β7/α4 βp in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering. J. Cell Biol. 117:179.
40. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301.
41. Alon, R., P. D. Kassner, M. W. Carr, E. B. Finger, M. E. Hemler, and T. A. Springer. 1995. The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. J. Cell. Biol 128:1243.
42. Altevogt, P., M. Hubbe, M. Ruppert, J. Lohr, P. Von Hoegen, M. Sammar, D. P. Andrew, L. McEvoy, M. J. Humphries, and E. C. Butcher. 1995. The α4 integrin chain is a ligand for α4 β7 and α4 β1. J. Exp. Med. 182:345.
43. Berlin, C., R. F. Bargatze, J. J. Campbell, U. H. von Andrian, M. C. Szabo, S. R. Hasslen, R. D. Nelson, E. L. Berg, S. L. Erlandsen, and E. C. Butcher. 1995. α4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell 80:413.