Elimination of free radionuclide by a chelating agent improves tumor- to-nontumor ratios following radioimmunotargeting with antibody labeled with 67Ga

Nuclear Medicine and Biology

Volumn 25, Issue 3, 1998, Pages 261-265

  Ryser, J E ^a,d   Rose, K ^a   Jones, R ^a   Pelegrin, A ^b   Donath, A ^a   Egeli, R ^a   Smith, A ^c   Offord, R E ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c PAUL SCHERRER INSTITUTE   (Switzerland)

^d Fondation des Grangettes   (Switzerland)

Author keywords

Antibodies; Cancer; Deferoxamine; Gallium; Radioimmunoscintigraphy

Indexed keywords

CHELATING AGENT; DEFEROXAMINE; GALLIUM 67; IMMUNOGLOBULIN F(AB')2 FRAGMENT; MONOCLONAL ANTIBODY GA 67; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG UPTAKE; ISOTOPE LABELING; KIDNEY; LIVER; MOUSE; NONHUMAN; SPLEEN; TISSUE DISTRIBUTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CHELATING AGENTS; COLONIC NEOPLASMS; DEFEROXAMINE; GALLIUM RADIOISOTOPES; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; KIDNEY; KINETICS; MICE; MICE, NUDE; RADIOIMMUNODETECTION; RADIOIMMUNOTHERAPY; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 0032054619     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(97)00189-3     Document Type: Article

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