Striatal dopamine dynamics are altered following an intranigral infusion of iron in adult rats

Free Radical Biology and Medicine

Volumn 24, Issue 6, 1998, Pages 988-993

  Maan Yuh Lin, Anya ^a,b   Yang, Chih Hsin ^a,c   Chai, Chok Yung ^a,b  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Dopamine dynamics; Free radical; In vivo electrochemistry; Iron; Nomifensine; Oxidative stress; Striatum; Substantia nigra

Indexed keywords

DOPAMINE; FREE RADICAL; IRON; NOMIFENSINE; POTASSIUM ION; URETHAN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINE UPTAKE; ELECTROCHEMICAL DETECTION; LIPID PEROXIDATION; MALE; NERVE ENDING; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA;

ANIMALS; BIOSENSING TECHNIQUES; CORPUS STRIATUM; DOPAMINE; ELECTROCHEMISTRY; FERROUS COMPOUNDS; INFUSIONS, PARENTERAL; IRON; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; RATS;

ANIMALIA;

EID: 0032054319     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00398-5     Document Type: Article

References (36)

1. Ames B. N., Shigenaga M. K., Hagen T. M. Oxidants, antioxidants and the degenerative disease of aging. Proc. Natl. Acad. Sci. USA. 90:1993;7915-7922.
2. Mecocci P., MacGarvey U., Kaufman A. E., Koontz D., Shoffner J. M., Wallace D. C., Beal M. F. Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann. Neurol. 34:1993;609-616.
3. Michel P. P., Vyas A., Agid Y. Toxic effects of iron for cultured mesencephalic dopaminergic neurons derived from rat embryonic brains. J. Neurochem. 59:1992;118-127.
4. Ben-Shachar D., Youdim M. B. H. Intranigral iron injection induces behavioral and biochemical "Parkinsonism" in rats. J. Neurochem. 57:1991;2133-2135.
5. Cass W. A., Gerhardt G. A., Zhang Z., Ovadia A., Gash D. M. Increase dopamine clearance in the non-lesioned striatum of rhesus monkeys with unilateral 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (MPTP) striatal lesions. Neurosci. Lett. 185:1995;52-55.
6. Chiueh C. C., Wu R. M., Mohanakumar K. P., Sternberger L. M., Krishina G., Obata T., Murry D. L. In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia. Ann. NY Acad. Sci. 738:1994;25-36.
7. Cohen G., Werner P. Free radicals, oxidative stress and neurodegeneration. Calne D.B. Neurodegenerative diseases. 1994;139-162 WB Saunders, Philadelphia.
8. Dexter D. T., Wells F. R., Lees A. J., Agid F., Agid Y., Jenner P., Marsden C. D. Increased nigral iron content and alteration in other metal ions occurring in brain in Parkinson's disease. J. Neurochem. 52:1994;1830-1836.
9. Halliwell B. Reactive oxygen species and the central nervous system. J. Neurochem. 59:1992;1609-1623.
10. 3H]dopamine uptake in rat striatal slices. Brain Res. 671:1995;321-324.
11. van Horne C., Hoffer B. J., Stromberg I., Gerhardt G. A. Clearance and diffusion of locally applied dopamine in normal and 6-hydroxydopamine-lesioned rat striatum. J. Pharmacol. Exper. Ther. 263:1992;1285-1292.
12. Olanow C. W. An introduction to the free radical hypothesis in Parkinson's disease. Ann. Neurol. 32:1992;S2-S9.
13. Perry T. L., Godin D. V., Hansen A. Parkinson's disease A disorder due to nigral glutathione deficiency . Neurosci. Lett. 33:1982;305-310.
14. Rauhala P., Parameswarannay K., Sziraki I., Lin A. M. Y., Chiueh C. C. S-nitrosothiols and nitric oxide, but not sodium nitroprusside protect nigrostriatal dopamine neurons against iron-induced oxidative stress in vivo. Synapse. 23:1996;58-60.
15. Schulz J. B., Henshaw D. R., Siwek D., Jenkins B. G., Ferrante R. J., Cipolloni P. B., Kowall N. W., Rosen B. R., Beal M. F. Involvement of free radicals in excitotoxicity in vivo. J. Neurochem. 64:1995;2239-2247.
16. Sengstock G. J., Olanow C. W., Dunn A. J., Arendash G. W. Iron induced degeneration of nigrostriatal neurons. Brain Res. Bull. 28:1992;645-649.
17. Sengstock G. J., Olanow C. W., Dunn A. J., Barone S. Jr, Arendash G. W. Progressive changes in striatal dopaminergic markers, nigral volume, and rotational behavior following iron infusion into the rat substantia nigra. J. Neurol. 130:1994;82-94.
18. Sofic E., Paulus W., Jellinger K., Riederer P., Youdim M. B. H. Selective increase of iron in substantia nigra zona compacta of Parkinsonian brains. J. Neurochem. 56:1991;978-982.
19. Sofic E., Lang K. W., Jellinger K., Riederer P. Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci. Lett. 142:1992;128-130.
20. Youdim M. B., Ben-Shachar D., Eshel G., Finberg J. P. M., Riederer P. The neurotoxicity of iron and nitric oxide relevance to the etiology of Parkinson's disease. Narabyashi H., Nagatsu T., Yanagisawa N., Mizuno Y. Adv. Neurology. 1993;259-266 Raven Press, New York.
21. Floyd R. A., Carney J. M. Free radicals damage to protein and DNA Mechanisms involved and relevant observation on brain undergoing oxidative stress . Ann. Neurol. 32:1992;S22-S27.
22. Wink D. A., Hanbauer I., Krishna M. C., DeGraff W., Gamson J., Mitchell J. B. Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species. Proc. Natl. Acad. Sci. USA. 90:1993;9813-9817.
23. Espino A., Cutillas B., Tortosa A., Ferrer I., Bartrons R., Ambrosio S. Chronic effects of single intranigral injections of 6-OHDA or MPP studied by microdialysis in free moving rats. Brain Res. 695:1995;151-157.
24. Zigmond M. J., Stricker E. M. Animal models of Parkinsonism using selective neurotoxins Clinical and basic implication . Int. Rev. Neurobiol. 31:1989;1-79.
25. Halliwell B., Gutteridge J. M. Oxygen toxicity, oxygen radicals, transition metals and diseases. Biochem. J. 219:1984;1-14.
26. Gerhardt G. A., Greg M. R., Hoffer B. J. Release of monoamines from striatum of rat and mouse evoked by local application of potassium Evaluation of a new in vivo electrochemical technique . J. Neurochem. 46:1986;842-850.
27. Tuomisto J. Nomifensine and its derivatives as possible tools for studying amine uptake. Eur. J. Pharmacol. 42:1977;101-106.
28. Paxinos, G.; Watson, C. The rat brain in stereotaxic coordinates. Raven Press: Academic Press; 1986.
29. Friedemann M. N. In vivo electrochemical studies of dopamine diffusion and clearance in the striatum of young and aged F344 rats. Age. 15:1992;23-28.
30. Gerhardt G. A., Oke A. F., Nagy G., Moghaddam B., Adams R. N. Nafion-coated electrodes with high selectivity for CNS electrochemistry. Brain Res. 290:1984;390-395.
31. Lin A. M. Y., Chai C. Y. Dynamic analysis of ethanol effects on NMDA-evoked dopamine overflow in rat striatum. Brain Res. 696:1995;15-20.
32. Gerhardt G. A., Palmer M. Characterization of the techniques of pressure ejection and microiontophoresis using in vivo electrochemistry. J. Neurosci. Methods. 22:1987;147-159.
33. Kikugawa K., Kato T., Beppu M., Haysaaka A. Fluorescent and crosslinked protein formed by free radical and aldehyde species generated during lipid peroxidation. Adv. Exp. Med. Biol. 266:1989;345-356.
34. Mokanakumar K. P., DeBartolomeis A., Wu R. M., Yeh K. J., Sternberger L. M., Peng S., Murphy D. L., Chiueh C. C. Ferrous citrate complex and nigral degeneration Evidence for free radical formation and lipid peroxidation . Ann. NY Acad. Sci. 738:1994;392-399.
35. Zaleska M. M., Nagy K., Floyd R. A. Iron-induced lipid peroxidation and inhibition of dopamine synthesis in striatum synaptosomes. Neurochem. Res. 14:1989;597-605.
36. Trendelenburg U. A kinetic analysis of extraneuronal uptake and metabolism of catecholamines. Physiol. Biochem. Pharmacol. 87:1980;33-115.