Amplification, expression, and steroid regulation of the preprogalanin gene in human breast cancer

Cancer Research

Volumn 58, Issue 7, 1998, Pages 1353-1357

  Ormandy, Christopher J ^a,c   Lee, Christine S L ^a   Ormandy, Helen F ^a   Fantl, Vera ^b   Shine, John ^a   Peters, Gordon ^b   Sutherland, Robert L ^a  

^a ST VINCENT S HOSPITAL   (Australia)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GALANIN; MITOGENIC AGENT; NEUROPEPTIDE; PROTEIN PRECURSOR;

ARTICLE; BREAST CANCER; CHROMOSOME 11Q; CONTROLLED STUDY; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; HORMONAL REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROGNOSIS;

BLOTTING, NORTHERN; BLOTTING, SOUTHERN; BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 11; DEXAMETHASONE; DIHYDROTESTOSTERONE; DNA, NEOPLASM; ESTROGENS; GALANIN; GENE AMPLIFICATION; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PROGESTINS; PROTEIN PRECURSORS; RNA, MESSENGER; STEROIDS; TUMOR CELLS, CULTURED;

EID: 0032054276     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Lidereau, R., Callahan, R., Dickson, C., Peters, G., Escot, C., and Ali, I. U. Amplification of the int-2 gene in primary human breast tumors. Oncogene Res., 2: 285-291, 1988.
2. Tsuda, H., Hirohashi, S., Shimosato, Y., Hirota, T., Tsugane, S., Yamamoto, H., Miyajima, N., Toyoshima, K., Yamamoto, T., Yokota, J., Yoshida, T., Sakamoto, H., Terada, M., and Sugimura, T. Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1. Cancer Res., 49: 3104-3108, 1989.
3. Tsuda, T., Tahara, E., Kajiyama, G., Sakamoto, H., Terada, M., and Sugimura, T. High incidence of coamplification of hst-1 and int-2 genes in human esophageal carcinomas. Cancer Res., 49: 5505-5508, 1989.
4. Adnane, J., Gaudray, P., Simon, M. P., Simony-Lafontaine, J., Jeanteur, P., and Theillet, C. Proto-oncogene amplification and human breast tumor phenotype. Oncogene, 4: 1389-1395, 1989.
5. Borg, A., Sigurdsson, H., Clark, G. M., Ferno, M., Fuqua, S. A., Olsson, H., Killander, D., and McGurie, W. L. Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis. Br. J. Cancer, 63: 136-142, 1991.
6. Lammie, G. A., and Peters, G. Chromosome 11q13 abnormalities in human cancer. Cancer Cells (Cold Spring Harbor), 3: 413-420, 1991.
7. Schuuring, E., Verhoeven, E., van Tinteren, H., Peterse, J. L., Nunnink, B., Thunnissen, F. B., Devilee, P., Cornelisse, C. J., van de Vijver, M. J., Mooi, W. J., and Michalides, R. J. Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer. Cancer Res., 52: 5229-5234, 1992.
8. Schuuring, E., Verhoeven, E., Mooi, W. J., and Michalides, R. J. Identification and cloning of two overexpressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas. Oncogene, 7: 355-361, 1992.
9. Seshadri, R., Lee, C. S. L., Hui, R., McCaul, K., Horsfall, D. J., and Sutherland, R. L. Cyclin D1 amplification is not associated with reduced overall survival in primary breast cancer but may predict early relapse in patients with features of good prognosis. Clin. Cancer Res., 2: 1177-1184, 1996.
10. Hui, R., Cornish, A. L., McClelland, R. A., Robertson, J. F. R., Blamey, R. W., Musgrove, E. A., Nicholson, R. I., and Sutherland, R. L. Cyclin D1 and estrogen receptor mRNA expression are positively correlated in primary breast cancer. Clin. Cancer Res., 2: 923-928, 1996.
11. Hui, R., Campbell, D. H., Lee, C. S. L., McCaul, K., Horsfall, D. J., Musgrove, E. A., Daly, R. J., Seshadri, R., and Sutherland, R. L. EMS1 amplification can occur independently of CCND1 or INT-2 amplification at 11q13 and may identify different phenotypes in primary breast cancer. Oncogene, 15: 1617-1623, 1997.
12. Buckley, M. F., Sweeney, K. J., Hamilton, J. A., Sini, R. L., Manning, D. L., Nicholson, R. I., deFazio, A., Watts, C. K., Musgrove, E. A., and Sutherland, R. L. Expression and amplification of cyclin genes in human breast cancer. Oncogene, 8: 2127-2133, 1993.
13. Campbell, D. H., deFazio, A., Sutherland, R. L., and Daly, R. J. Expression and tyrosine phosphorylation of EMS1 in human breast cancer cell lines. Int. J. Cancer, 68: 485-492, 1996.
14. Ali, I. U., Merlo, G., Callahan, R., and Lidereau, R. The amplification unit on chromosome 11q13 in aggressive primary human breast tumors entails the bcl-1, int-2 and hst loci. Oncogene, 4: 89-92, 1989.
15. Karlseder, J., Zeillinger, R., Schneeberger, C., Czerwenka, K., Speiser, P., Kubista, E., Birnbaum, D., Gaudray, P., and Theillet, C. Patterns of DNA amplification at band q13 of chromosome 11 in human breast cancer. Genes Chromosomes Cancer, 9: 42-48, 1994.
16. Szepetowski, P., Simon, M. P., Grosgeorge, J., Huebner, K., Bastard, C., Evans, G. A., Tsujimoto, Y., Birnbaum, D., Theillet, C., and Gaudray, P. Localization of 11q13 loci with respect to regional chromosomal breakpoints. Genomics, 12: 738-744, 1992.
17. Szepetowski, P., Courseaux, A., Carle, G. F., Theillet, C., and Gaudray, P. Amplification of 11q13 DNA sequences in human breast cancer: D11S97 identifies a region tightly linked to BCL1 which can be amplified separately. Oncogene, 7: 751-755, 1992.
18. Szepetowski, P., Ollendorff, V., Grosgeorge, J., Courseaux, A., Birnbaum, D., Theillet, C., and Gaudray, P. DNA amplification at 11q13.5-q14 in human breast cancer. Oncogene, 7: 2513-2517, 1992.
19. Gaudray, P., Szepetowski, P., Escot, C., Birnbaum, D., and Theillet, C. DNA amplification at 11q13 in human cancer: from complexity to perplexity. Mutat. Res., 276: 317-328, 1992.
20. Evans, H., Baumgartner, M., Shine, J., and Herzog, H. Genomic organization and localization of the gene encoding human preprogalanin. Genomics, 18: 473-477, 1993.
21. Evans, H. F., and Shine, J. Human galanin: molecular cloning reveals a unique structure. Endocrinology, 129: 1682-1684, 1991.
22. 2+ mobilization, inositol phosphate accumulation, and clonal growth in small cell lung cancer cells. Cancer Res., 51: 1674-1679, 1991.
23. Sethi, T., and Rozengurt, E. Multiple neuropeptides stimulate clonal growth of small cell lung cancer: effects of bradykinin, vasopressin, cholecystokinin, galanin, and neurotensin. Cancer Res., 51: 3621-3623, 1991.
24. Sethi, T., Langdon, S., Smyth, J., and Rozengurt, E. Growth of small cell lung cancer cells: stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo. Cancer Res., 52 (Suppl.): 2737s-2742s, 1992.
25. Crawley, J. N. Biological actions of galanin. Regul. Pept., 59: 1-16, 1995.
26. Vrontakis, M. E., Torsello, A., and Friesen, H. G. Galanin. J. Endocrinol. Invest., 14: 785-794, 1991.
27. Casey, G., Smith, R., McGillivray, D., Peters, G., and Dickson, C. Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene. Mol. Cell. Biol., 6: 502-510, 1986.
28. Krissansen, G. W., Owen, M. J., Verbi, W., and Crumpton, M. J. Primary structure of the T3 γ subunit of the T3/T cell antigen complex deduced from cDNA sequences: evolution of the T3 γ and δ subunits. EMBO J., 8: 1799-1808, 1996.
29. Misrahi, M., Atger, M., D'Auriol, L., Loosfelt, H., Meriel, C., Fridlansky, F., Guiochon-Mantel, A., Galibert, A., and Milgrom, E. Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA. Biochem. Biophys. Res. Commun., 143: 740-748, 1987.
30. Chan, Y. L., Guiell, R., Noller, H. F., and Wool, I. G. The nucleotide sequence of a rat 18S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18S ribosomal nucleic acid. J. Biol. Chem., 259: 224-230, 1984.
31. Reddel, R. R., Murphy, L. C., Hall, R. E., and Sutherland, R. L. Differential sensitivity of human breast cancer cells to the growth inhibitory effects of tamoxifen. Cancer Res., 45: 1525-1531, 1985.
32. Fantl, V., Richards, M. A., Smith, R., Lammie, U. A., Johnstone, G., Allen, D., Gregory, W., Peters, G., Dickson, C., and Bames, D. M. Gene amplification on chromosome band 11q13 and oestrogen receptor status in breast cancer. Eur. J. Cancer, 26: 423-429, 1990.
33. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
34. Merchenthaler, I., Lopez, F. J., and Negro-Vilar, A. Anatomy and physiology of central galanin-containing pathways. Prog. Neurobiol. (NY), 40: 711-769, 1993.
35. Vrontakis, M. E., Peden, L. M., Duckworth, M. L., and Friesen, H. G. Isolation and characterization of a complementary DNA (galanin) clone from estrogen-induced pituitary tumor messenger RNA. J. Biol. Chem., 262: 16755-16758, 1987.
36. Kaplan, L. M., Gabriel, S. M., Koenig, J. I., Sunday, M. E., Spindel, E. R., Martin, J. B., and Chin, W. W. Galanin is an estrogen-inducible, secretory product of the rat anterior pituitary. Proc. Natl. Acad. Sci. USA, 85: 7408-7412, 1988.
37. O'Halloran, D. J., Jones, P. M., Steel, J. H., Gon, G., Giaid, A., Ghatei, M. A., Polak, J. M., and Bloom, S. R. Effect of endocrine manipulation on anterior pituitary galanin in the rat. Endocrinology, 127: 467-475, 1990.
38. Torsello, A., Vrontakis, M. E., Schroedter, I. C., Vuille, J. C., Ikejiani, C., and Friesen, H. G. Steroids and tissue-specific modulation of galanin gene expression in the male rat reproductive system. Endocrinology, 130: 3301-3306, 1992.
39. Xu, J., Tyan, T., Cedrone, E., Savaraj, N., and Wang, N. Detection of 11q13 amplification as the origin of a homogeneously staining region in small cell lung cancer by chromosome microdissection. Genes Chromosomes Cancer, 17: 172-178, 1996.
40. Ormandy, C. J., Camus, A., Barra, J., Damotte, D., Lucas, B., Buteau, H., Brousse, N., Babinet, C., Binart, N., and Kelly, P. A. Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse. Genes Dev., 11: 167-178, 1997.
41. Ormandy C. J., Binart, N., and Kelly, P. A. Mammary gland development in prolactin receptor knockout mice. J. Mamm. Gland Biol. Neoplasia, 2: 355-364, 1997.
42. Das, R., and Vonderhaar, B. K. Prolactin as a mitogen in mammary cells. J. Mamm. Gland Biol. Neoplasia, 2: 29-40, 1997.
43. Patton, S., and Neville M. C. Maternal adaptation to lactation. J. Mamm. Gland Biol. Neoplasia, 2: 201-203, 1997.
44. Eriksson, M., Lindh, B., Uvnas-Moberg, K., and Hokfelt, T. Distribution and origin of peptide-containing nerve fibres in the rat and human mammary gland. Neuroscience, 70: 227-245, 1996.