Chronic disulfiram treatment effects on intranasal cocaine administration: Initial results

Biological Psychiatry

Volumn 43, Issue 7, 1998, Pages 540-543

  McCance Katz, Elinore F ^a,b   Kosten, Thomas R ^a,b   Jatlow, Peter ^b  

^a VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol; Antabuse; Cocaine; Disulfiram; Drug interaction; Pharmacotherapy

Indexed keywords

ALCOHOL; COCAINE; DISULFIRAM;

ADULT; ALCOHOLISM; ARTICLE; CLINICAL ARTICLE; COMORBIDITY; DRUG DEPENDENCE TREATMENT; DRUG EFFECT; EUPHORIA; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; SUBSTANCE ABUSE;

ADMINISTRATION, INTRANASAL; ADULT; ALCOHOL DETERRENTS; BLOOD PRESSURE; COCAINE; DISULFIRAM; DOUBLE-BLIND METHOD; FEMALE; HEART RATE; HUMANS; MALE; SUBSTANCE-RELATED DISORDERS;

EID: 0032054260     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(97)00506-4     Document Type: Article

References (16)

1. Ambre JJ, Belknap SM, Nelson J, Ruo TI, Shin S, Atkinson AJ (1988): Acute tolerance to cocaine in humans. Clin Pharmacol Ther 44:1-8.
2. Benowitz N (1993): Clinical pharmacology and toxicology of cocaine. Pharmacol Toxicol 72:3-12.
3. Carroll K, Ziedonis D, O'Malley S, McCance-Katz E, Gordon L, Rounsaville B (1993): Pharmacologic interventions for abusers of alcohol and cocaine: A pilot study of disulfiram versus naltrexone. J Drug Addiction 2:77-79.
4. Carroll KM, Nich C, Ball SA, McCance-Katz EF, Rounsaville BJ (in press): Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram. Addictions.
5. Faiman MD (1979): Biochemical pharmacology of disulfiram. In: Majehowicz E, Nobel EP, editors. Biochemistry and Pharmacology of Ethanol, vol 2. New York: Plenum Press, pp 325-348.
6. Fischman MW, Schuster CR, Hatano Y (1983): A comparison of the subjective and cardiovascular effects of cocaine and lidocaine in humans. Pharmacol Biochem Behav 18:123-127.
7. Fischman MW, Schuster CR, Javaid J, Hatano Y, Davis J (1985): Acute tolerance to the cardiovascular and subjective effects of cocaine. J Pharmacol Exp Ther 235:677-682.
8. Foltin RW, Fischman MW (1991): Smoked and intravenous cocaine in humans: Acute tolerance, cardiovascular and subjective effects of cocaine. J Pharmacol Exp Ther 257: 247-261.
9. Grant BF, Harford TC (1990): Current and simultaneous use of alcohol with cocaine: Results of a national survey. Drug Alcohol Depend 25:97-104.
10. Hameedi FA, Rosen MI, McCance-Katz EF, McMahon TJ, Price LH, Jatlow PI, et al (1995): Behavioral, physiological and pharmacological interaction of cocaine and disulfiram. Biol Psychiatry 37:560-563.
11. Helander A, Carlsson S (1990): Use of leukocyte aldehyde dehyrogenase activity to monitor inhibitory effect of disulfiram treatement. Alcoholism Clin Exp Res 14:48-52.
12. Jatlow P, Elsworth JD, Bradberry CW, Winger G, Taylor JR, Russell R, et al (1991): Cocaethylene: A neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion. Life Sci 48:1787-1794.
13. McCance EF, Price LH, Kosten TR, Jatlow PI (1995): Cocaethylene: Pharmacology, physiology, and behavioral effects in humans. J Pharmacol Exp Ther 274:215-223.
14. McCance-Katz EF, Price LH, McDougle CJ, Kosten TR, Black JE, Jatlow PI (1993): Concurrent cocaine-ethanol ingestion in humans: Pharmacology, physiology, behavior, and the role of cocaethylene. Psychopharmacology 111:39-46.
15. Van Etten ML, Higgins ST, Budney AJ, Bickel WK, Hughes JR, Foerg F (1994): Disulfiram therapy in patients abusing cocaine and alcohol. NIDA Res Monogr 141:443.
16. Weiss RD, Mirin SM, Griffin ML, Michael JL (1988): Psychopathology in cocaine abusers - Changing trends. J Nerv Ment Dis 176:719-725.