Magnesium deficiency exacerbates brain injury and stroke mortality induced by alcohol: A 31P-NMR in vivo study

Alcohol

Volumn 15, Issue 3, 1998, Pages 181-183

  Altura, Burton M ^a,b   Gebrewold, Asefa ^a   Zhang, Aimin ^a   Altura, Bella T ^a,b   Gupta, Raj K ^c  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b Downstate Health Sciences University   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

31P NMR spectroscopy; Alcohol hemorrhagic stroke; Intracellular brain pH; Mg2+ (cytosolic free)

Indexed keywords

ALCOHOLISM; ANIMAL EXPERIMENT; ARTICLE; BRAIN INJURY; CELL PH; DISEASE ASSOCIATION; DOSE RESPONSE; MAGNESIUM DEFICIENCY; MALE; NONHUMAN; RAT; STROKE;

ANIMALS; BRAIN; BRAIN INJURIES; CEREBROVASCULAR DISORDERS; DIET; ETHANOL; HYDROGEN-ION CONCENTRATION; MAGNESIUM; MAGNESIUM DEFICIENCY; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PHOSPHATES; PHOSPHOCREATINE; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0032054030     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(97)00107-9     Document Type: Article

References (10)

1. Altura B. M., Altura B. T. Alcohol, the cerebral circulation, and strokes. Alcohol. 1:1984;325-331.
2. Altura B. M., Altura B. T. Magnesium in cardiovascular biology. Sci. Am. Sci. Med. 2:1995;28-36.
3. Altura B. M., Altura B. T., Gupta R. K. Alcohol intoxication results in rapid loss in free magnesium in brain and disturbances in brain bioenergetics. Relation to cerebrovasospasm, alcohol-induced strokes, and barbiturate anesthesia-induced deaths Magnesium Trace Elem. 10:1992;122-135.
4. Altura B. M., Zhang A., Cheng T. P.-O., Altura B. T. Ethanol promotes rapid depletion of intracellular free Mg in cerebral vascular smooth muscle cells. Possible relation to alcohol-induced behavioral and stroke-like effects Alcohol. 10:1993;563-566.
5. 31P-NMR in vivo study Alcohol. 12:1995;131-136.
6. Anonymous Binge drinking and stroke. 1983;660-661, Lancet ii.
7. Camargo C. A. Jr. Moderate alcohol consumption and stroke. The edipedmiologic evidence. Stroke. 20:1989;1611-1626.
8. Donahue R. P., Abbott P. D., Reed D. M., Yano K. Alcohol and hemorrhagic stroke. JAMA. 255:1986;2311-2314.
9. Vink R., Heath D. L., McIntosh T. K. Acute and prolonged alterations in brain free magnesium following fluid percussion-induced brain trauma in rats. J. Neurochem. 66:1996;2477.
10. i. Relation to etiology of alcohol-induced stroke Alcohol. 14:1997;367-371.