An economic synthesis of 1,2,3,4-tetra-O-acetyl-5-thio-D-xylopyranose and its transformation into 4-substituted-phenyl 1,5-dithio-D-xylopyranosides possessing antithrombotic activity

Carbohydrate Research

Volumn 308, Issue 3-4, 1998, Pages 297-310

  Bozó, Éva ^a   Boros, Sándor ^a   Kuszmann, János ^a   Gács Baitz, Eszter ^b   Párkányi, László ^b  

^a Institute for Drug Research Budapest   (Hungary)

^b CTRL RES INSTITUTE FOR CHEMISTRY   (Hungary)

Author keywords

1,2 O Isopropylidene D xylofuranose cyclic sulfite and sulfate derivatives; 5 Thio D xylose derivatives; C Glycosides; Glycosidation reactions; Oral antithrombotic activity; Thioglycosides

Indexed keywords

1,2,3,4 TETRA O ACETYL 5 THIO DEXTRO XYLOPYRANOSE; THIOGLYCOSIDE; UNCLASSIFIED DRUG;

ANTICOAGULATION; ARTICLE; CONFORMATION; DEACETYLATION; DIASTEREOISOMER; DRUG ACTIVITY; DRUG SYNTHESIS; GLYCOSYLATION; HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLOGRAPHY; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRINOLYTIC AGENTS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RATS; SULFUR COMPOUNDS; XYLOSE;

THIA;

EID: 0032053289     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6215(98)00088-3     Document Type: Article

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