Analgesic efficacy and safety of nonpreserved ketorolac tromethamine ophthalmic solution following radial keratotomy

American Journal of Ophthalmology

Volumn 125, Issue 4, 1998, Pages 472-480

  Yee, Richard W ^a   Grene, R Bruce ^c   Casebeer, J Charles ^c   Durrie, Daniel S ^b   Price Jr , Francis W ^c   Cheetham, Janet K ^c   Blissit, Mary Lou ^c   DeGryse, Ronald ^c   Reis, Brenda ^c   Rosenthal, Allan ^c  

^a UNIVERSITY OF TEXAS   (United States)

^b Hunkler Eye Clinic   (United States)

^c Hunkler Eye Clinic ^*

Author keywords

[No Author keywords available]

Indexed keywords

KETOROLAC TROMETAMOL; PARACETAMOL; PROMETHAZINE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ERYTHEMA; EYELID EDEMA; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RADIAL KERATOTOMY; RANDOMIZED CONTROLLED TRIAL;

EID: 0032052709     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9394(99)80187-1     Document Type: Article

References (15)

1. 1. Juan H. Prostaglandins as modulators of pain. Gen Pharmacol 1978;9:403-409.
2. 2. Ferreira SH, Moncada S, Vane JR. Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. Br J Pharmacol 1973;49:86-97.
3. 3. Rooks WH. The pharmacologic activity of ketorolac tromethamine. Pharmacotherapy 1990;10:30S-32S.
4. 4. DiPalma JR. Ketorolac: an injectable NSAID. Am Fam Phys 1991;43:207-210.
5. 5. Resman-Targoff BH. Ketorolac: a parenteral nonsteroidal anti-inflammatory drug. DICP 1990;24:1098-1104.
6. 6. Donnenfeld ED, Selkin BA, Perry HD, et al. Controlled evaluation of a bandage contact lens and a topical nonsteroidal anti-inflammatory drug in treating traumatic corneal abrasions. Ophthalmology 1995;102:979-984.
7. 7. Fry LL. Efficacy of diclofenac sodium solution in reducing discomfort after cataract surgery. J Cataract Refract Surg 1995;21:187-190.
8. 8. Arshinoff S, D'Addario D, Sadler C, Bilotta R, Johnson TM. Use of topical nonsteroidal anti-inflammatory drugs in excimer laser photorefractive keratectomy. J Cataract Refract Surg 1994;20(suppl):216-222.
9. 9. Stein R, Stein HA, Cheskes A, Symons S. Photorefractive keratectomy and postoperative pain. Am J Ophthalmol 1994;117:403-405.
10. 10. Epstein RL, Laurence EP. Relative effectiveness of topical ketorolac and topical diclofenac on discomfort after radial keratotomy. J Cataract Refract Surg 1995;21:156-159.
11. 11. Binder PS. Excimer laser photoablation: miracle or menace? J Ophthalmic Nurs Technol 1994;13:61-76.
12. 12. Tinkelman DG, Rupp G, Kaufman H, Pugely J, Schultz N. Double-masked paired-comparison clinical study of ketorolac tromethamine 0.5% ophthalmic solution compared with placebo eyedrops in the treatment of seasonal allergic conjunctivitis. Surv Ophthalmol 1993;38(suppl):133-140.
13. 13. Ballas Z, Blumenthal M, Tinkelman DG, Kriz R, Rupp G. Clinical evaluation of ketorolac tromethamine 0.5% ophthalmic solution for the treatment of seasonal allergic conjunctivitis. Surv Ophthalmol 1993;38(suppl):141-148.
14. 14. Flach AJ, Lavelle CJ, Olander KW, Retzlaff JA, Sorenson LW. The effect of ketorolac tromethamine solution 0.5% in reducing postoperative inflammation after cataract extraction and intraocular lens implantation. Ophthalmology 1988;95: 1279-1284.
15. 15. Flach AJ, Graham J, Krugeer LP, Stegman RC, Tanenbaum L. Quantitative assessment of postsurgical breakdown of the blood aqueous barrier following administration of ketorolac tromethamine solution: a double-masked, paired-comparison vehicle-placebo solutions study. Arch Ophthalmol 1988;106: 344-347.