Estrogen receptor mediated inhibition of cancer cell invasion and motility: An overview

Journal of Steroid Biochemistry and Molecular Biology

Volumn 65, Issue 1-6, 1998, Pages 163-168

  Rochefort, Henri ^a   Platet, Nadine ^a   Hayashido, Yasutaka ^a,b   Derocq, Danielle ^a   Lucas, Annick ^a   Cunat, Séverine ^a   Garcia, Marcel ^a  

^a INSERM   (France)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; FIBRONECTIN; FIBULIN;

BREAST CARCINOMA; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CELL MOTILITY; CONFERENCE PAPER; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; METASTASIS; OVARY CARCINOMA;

BREAST NEOPLASMS; CELL MOVEMENT; ESTROGENS; FEMALE; HUMANS; NEOPLASM INVASIVENESS; OVARIAN NEOPLASMS; RECEPTORS, ESTROGEN; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032052261     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(98)00010-7     Document Type: Conference Paper

References (40)

1. Pike M. C., Krailo M. D., Henderson B. E., Casagrande J. T., Hoel D. G. 'Hormonal' risk factors, 'breast tissue age' and the age-incidence of breast cancer. Nature. 303:1983;767-770.
2. Rao B. R., Slotman B. J. Endocrine factors in common epithelial ovarian cancer. Endocr. Rev. 12:1991;14-26.
3. Dickson R. B., McManaway M. E., Lippman M. E. Estrogen-induced factors of breast cancer cells partially replace estrogen to promote tumor growth. Science. 232:1986;1540-1544.
4. Chalbos D., Vignon F., Keydar I., Rochefort H. Estrogens stimulate cell proliferation and induce secretory proteins in a human breast cancer cell line (T47D). J. Clin. Endocrin. Metab. 55:1982;276-283.
5. Price J. E., Polyzos A., Zhang R. D., Daniels M. D. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res. 50:1990;717-721.
6. Thompson E. W., Paik S., Brünner N., Sommers C. L., Zugmaier G., Clarke R., Shima T. B., Torri J., Donahue S., Lippman M. E. Association of increased basement membrane-invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J. Cell Physiol. 150:1992;534-544.
7. Rochefort, H., Oestrogen- and anti-oestrogen-regulated genes in human breast cancer. In Non-Reproductive Actions of Sex Steroids, CIBA Foundation Symposium 191. John Wiley and Sons, Chichester, U.K., 1995, pp. 254-268.
8. Lefebre O., Chenard M. P., Masson R., Linares J., Dierich A., LeMeur M., Wending C., Tomasetto C., Chambon P., Rio M. C. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil peptide. Science. 274:1996;259-262.
9. Holt J. T., Thompson M. E., Szabo C., Robinson-Benion C., Arteaga C. L., King M. C., Jensen R. A. Growth retardation and tumour inhibition by BRCA1. Nature Genet. 12:1996;298-302.
10. Rochefort H., Capony F., Garcia M., Cavaillès V., Freiss G., Chambon M., Morisset M., Vignon F. Estrogen-induced lysosomal proteases secreted by breast cancer cells. A role in carcinogenesis? J. Cell Biochem. 35:1987;17-29.
11. Garcia M., Platet N., Laurent V., Derocq D., Brouillet J. P., Rochefort H. Biological and clinical significance of cathepsin D in breast cancer metastasis. Stem Cells. 14:1996;642-650.
12. Vignon F., Capony F., Chambon M., Freiss G., Garcia M., Rochefort H. Autocrine growth stimulation of the MCF7 breast cancer cells by the estrogen-regulated 52K protein. Endocrinology. 118:1986;1537-1545.
13. Garcia M., Derocq D., Pujol P., Rochefort H. Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency. Oncogene. 5:1990;1809-1814.
14. Liaudet E., Derocq D., Rochefort H., Garcia M. Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors. Cell Growth Differ. 6:1995;1045-1052.
15. Liotta L. A., Steeg P. S., Stetler-Stevenson W. G. Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation. Cell. 64:1991;327-336.
16. Johnson M. D., Torri J. A., Lippman M. E., Dickson R. B. The role of cathepsin D in the invasiveness of human breast cancer cells. Cancer Res. 53:1993;873-877.
17. Briozzo P., Badet J., Capony F., Pieri I., Montcourrier P., Barritault P., Rochefort H. MCF7 mammary cancer cells respond to bFGF and internalize it following its release from extracellular matrix: A permissive role of cathepsin D. Exp. Cell Res. 194:1991;252-259.
18. Saftig P., Hetman M., Schmahl W., Weber K., Heine L., Mossmann H., Köster A., Hess B., Evers M., Von Figura K., Peters C. Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the mucosa and profound destruction of lymphoid cells. EMBO J. 14:1995;3599-3608.
19. Albini A., Iwamoto Y., Kleinman H. K., Martin G. R., Aaronson S. A., Kozlowski J. M., McEwan R. N. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res. 47:1987;3239-3245.
20. Langdon S. P., Hirst G. L., Miller E. P., Hawkins R. A., Tesdale A. L., Smyth J. F., Miller W. R. The regulation of growth and protein expression by estrogen in vitro: A study of 8 human ovarian carcinoma cell lines. J. Steroid Biochem. Mol. Biol. 50:1994;131-135.
21. Galtier-Dereure F., Capony F., Maudelonde T., Rochefort H. Estradiol stimulates cell growth and secretion of pro-cathepsin D and 120 kDa protein in the human ovarian cancer cell line BG-1. J. Clin. Endocrinol. Metab. 75:1992;1497-1502.
22. Clinton G., Rougeot C., Derancourt J., Roger P., Defrenne A., Godyna S., Argraves W. S., Rochefort H. Estrogens increase the expression of fibulin-1, an extracellular matrix protein, secreted by human ovarian cancer cells. Proc. Natl. Acad. Sci. USA. 93:1996;316-320.
23. Argraves W. S., Tran H., Burgess W. H., Dickerson K. Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure. J. Cell Biol. 111:1990;3155-3164.
24. Pujol, P., Chalbos, D. and Rochefort, H., Estradiol induces fibulin-1 mRNA in ovarian cancer cell lines. In preparation.
25. Roger, P., Lucas, A., Baldet, P. and Rochefort, H., Expression of fibulin-1 and estrogen receptor α in human ovarian epithelial tumors. Submitted.
26. Hayashido, Y., Lucas, A., Rougeot, C., Godyna, S., Argraves, W. S. and Rochefort, H., Estradiol and fibulin-1 inhibit motility of human ovarian and breast cancer cells induced by fibronectin. Int. J. Cancer 75 (1998) 654-658.
27. Platet, N., Derocq, D., Cunat, S., Rochefort, H. and Garcia, M., Inhibition of in vitro invasiveness of human breast cancer cells by transfected estrogen receptor before and after its activation by estrogen. Submitted.
28. Albini A., Graf J., Kitten G. T., Kleinman H. K., Martin G. R., Veillette A., Lippman M. E. 17β-estradiol regulates and v-Ha-ras transfection constitutively enhances MCF7 breast cancer cell interactions with basement membrane. Proc. Natl. Acad. Sci. USA. 83:1986;8182-8186.
29. Garcia, M., Derocq, D., Platet, N., Bonnet, S., Brouillet, J. P., Touitou, I. and Rochefort, H., Both estradiol and tamoxifen decrease proliferation and invasiveness of cancer cells transfected with a mutated estrogen receptor. J. Steroid Biochem. Mol. Biol., 1997, 61, in press.
30. Jiang S.-Y., Langan-Fahey S. M., Stella A., McCague R., Jordan V. C. Point mutation of estrogen receptor (ER) at the ligand binding domain changes the pharmacology of antiestrogens in ER-negative breast cancer cells stably expressing cDNA's for ER. Mol. Endocrinol. 6:1992;2167-2174.
31. Garcia M., Derocq D., Freiss G., Rochefort H. Activation of estrogen receptor transfected in a receptor negative breast cancer cell line decreases the metastatic and invasive potential of the cells. Proc. Natl. Acad. Sci. USA. 89:1992;11538-11542.
32. Philips A., Chalbos D., Rochefort H. Estradiol increases and antiestrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells, without affecting c-fos and c-jun synthesis. J. Biol. Chem. 268:1993;14103-14108.
33. Koop S., Schmidt E. E., MacDonald I. C., Morris V. L., Khokha R., Grattan M., Leone J., Chambers A. F., Groom A. Independence of metastatic ability and extravasation: Metastatic ras-transformed and control fibroblasts extravasate equally well. Proc. Natl. Acad. Sci. USA. 93:1996;11080-11084.
34. Chappell S. A., Walsh T., Walker R. A., Shaw J. A. Loss of heterozygosity at chromosome 6q in preinvasive and early invasive breast carcinomas. Br. J. Cancer. 75:1997;1324-1329.
35. Lastowska M. A., Lillington D. M., Shelling A. N., Cooke I., Gibbons B., Young B. D., Ganesan T. S. Fluorescence in situ hybridisation analysis using cosmid probes to define chromosome 6q abnormalities in ovarian carcinoma cell lines. Cancer Genet. Cytogenet. 77:1994;99-105.
36. Welch D. R., Chen P., Miele M. E., McGary C. T., Bower J. M., Stanbridge E. J., Weissman B. E. Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity. Oncogene. 9:1994;255-262.
37. Massot O., Baskevitch P. P., Capony F., Garcia M., Rochefort H. Estradiol increases the production of 1-antichymotrypsin in MCF7 and T47D human breast cancer cell lines. Mol. Cell. Endocrinol. 42:1985;207-214.
38. Sheng S., Carey J., Seftor E. A., Dias L., Hendrix M. J. Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc. Natl. Acad. Sci. USA. 93:1996;11669-11674.
39. Migliaccio A., Di Domenico M., Castoria G., de Falco A., Bontempo P., Nola E., Auricchio F. Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells. EMBO J. 15:1996;1292-1300.
40. Kuiper G. G. J. M., Carlsson B., Grandien K., Enmark E., Häggblad J., Nilsson S., Gustafsson J. A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β Endocrinology. 138:1997;863-870.