Treatment with AC pulsed electromagnetic fields normalizes the latency of the visual evoked response in a multiple sclerosis patient with optic atrophy

International Journal of Neuroscience

Volumn 93, Issue 3-4, 1998, Pages 239-250

  Sandyk, Reuven ^a  

^a TOURO COLLEGE   (United States)

Author keywords

Demyelination; Electromagnetic fields; Melatonin; Multiple sclerosis; Optic nerve; Optic neuritis; Opticatrophy; Secrotonin; Visual evoked response

Indexed keywords

EID: 0032052134     PISSN: 00207454     EISSN: None     Source Type: Journal    
DOI: 10.3109/00207459808986429     Document Type: Article

References (68)

1. Adams, R. D. & Victor, M. (1985). Principles of neurology, 3rd Edition, pp. 699-717. (McGraw-Hill Book Company, New York).
2. Aldegunde, M., Miguez, I. & Veira, J. (1985) "Effects of pinealectomy on regional brain serotonin metabolism," International Journal of Neuroscience, 26, 9-13.
3. Asselman, P., Chadwick, D. W. & Marsden, C. D. (1975). "Visual evoked responses in the diagnosis and management of patients suspected of multiple sclerosis," Brain, 98, 261-282.
4. Baumgarten, H G & Lachenmayer, L. (1985). "Anatomical features and physiological properties of central serotonin neurons," Pharmacopsychiatrie, 18, 180-187.
5. Bawin, S. M. & Adey, W. R. (1976). "Sensitivity of calcium binding in cerebral tissue to weak environmental electric fields oscillating at low frequency." Proceedings of the National Academy of Sciences, USA, 73, 1999-2003.
6. Bhaskar, P. A., Vanchilingam, S., Bhaskar, A , Devaprabhu, A. & Ganesan, R. A. (1986). "Effect of L-dopa on visual evoked potential in patients with Parkinson's disease," Neurology, 36, 1119-1121.
7. Blackman, C. F (1988). Stimulation of brain tissue in vitro by extremely low frequency, low intensity, sinusoidal electromagnetic fields. In M.E. O'Connor & R.H. Lovely (eds.). Electromagnetic fields and neurobehavioral function. (Alan R. Liss, New York).
8. Bodis-Wollner, I., Yahr, M. D. & Thornton, J. (1980) Visual evoked potentials and the severity of Parkinson's disease In F.C. Rose & R. Capildeo (eds.), Research progress in parkinson's disease, pp. 126-137 (Pitman Medical, Kent)
9. Bodis-Wollner, I., Yahr, M D., Mylin, L. & Thornton, J (1982). "Dopaminergic deficiency and delayed visual evoked potentials in humans," Annals of Neurology, 11, 478-483.
10. Borst, J G. G. & Sakmann, B. (1996). "Calcium influx and transmitter release in a fast CNS synapse," Nature, 383, 431-434.
11. Bubenick, G. A. & Purtill, R. A. (1980). "The role of melatonin and dopamine in retinal physiology," Canadian Journal of Physiology and Pharmacology. 58, 1457-1462.
12. Claveria, L E., Curzon, G., Harrison, M. J. G. & Kantamaneni, B D. (1974). "Amme metabolites in the cerebrospinal fluid of patients with disseminated sclerosis," Journal of Neurology, Neurosurgery and Psychiatry, 37, 715-718.
13. Cutler, J. R., Aminoff, M J. & Brant-Zawadzki, M. (1986). "Evaluation of patients with multiple sclerosis by evoked potentials and magnetic resonance imaging: a comparative study," Annals of Neurology, 20, 645-648
14. Davidson, D., Pullar, I. A., Mawdsley, C., Kinloch, N. & Yates, M. (1977). "Monoamine metabolites in cerebrospinal fluid in multiple sclerosis," Journal of Neurology, Neurosurgery and Psychiatry, 40, 741-745.
15. Dubocovich, M. L. (1983). "Melatonin as a potent modulalor of dopamine release in the retina." Nature, 306, 782-784.
16. Dyer, R S., Howell, W. E. & MacPhail, R. C. (1981) "Dopamine depletion slows retinal transmission," Experimental Neurology, 71, 326-340.
17. Gawel, M. J., Das, P. & Vincent, S. (1980). Visual and auditory evoked responses in Parkinson's disease. In F.C. Rose & R. Capildeo (eds.), Research progress in parkinson's disease, pp. 138-146 (Pitman Medical, Kent).
18. Gern, W. A. & Ralph, C. L. (1979). "Melatonin synthesis by the retina," Science, 204, 183-184.
19. Greenberg, D. A. (1997). "Calcium channels in neurological disease," Annals of Neurology, 42, 275-282.
20. Halliday, A. M. (1978). Clinical applications of evoked potentials. In W.B. Matthews & G.H. Glaser (eds.), Recent advances in clinical neurology, pp. 47-73 (Churchill Livingstone, Edinburgh).
21. Halliday, A M. & Wakefield, G. W. (1963) "Cerebral evoked potentials in patients with dissociated sensory loss," Journal of Neurology, Neurosurgery and Psychiatry, 26, 211-219.
22. Halliday, A. M. & McDonald, W. I. (1977). "Pathophysiology of demyelinating disease," British Medical Bulletin, 33, 21-27.
23. Halliday, A. M., McDonald, W. I. & Mushin, I. (1977). Visual evoked potentials in patients with demyelinating disease. In Desmedt, J.E. (ed.), Visual evoked potentials in man: new developments, pp 438-449 (Clarendon Press, Oxford).
24. Harrer, G. & Fischbach, R. (1973). "Uber die Wirkung bestimmter aminosauren auf das ergebniss des unberwarmungstests bein multiple sclerose kranken," Journal of Neural Transmission, 34, 205-214.
25. Haymaker, W. (1969). Bing's local diagnosis in neurological diseases, pp 357-359. (The C.V. Mosby Company, Saint Louis).
26. Holder, G. E., Bartlett, J. R., Bridges, P. K., Kantamanei, B. D. & Curzon, G. (1980). "Correlation between transmitter metabolite concentrations in human ventricular cerebrospinal fluid and pattern visual evoked potentials," Brain Research, 188, 582-586.
27. Hopper, C. L., Matthews, C. G. & Cleeland, C. S (1972). "Symptom instability and thermoregulation in multiple sclerosis," Neurology, 22, 142-148.
28. Johansson, B. & Roos, B. E. (1974). "5-hydroxyindoleacetic acid in cerebrospinal fluid of patients with neurological diseases," European Neurology, 11, 37-45.
29. Kisser, W. & Harrer, G. (1974), "Amino acid determinations in serum of patients with multiple sclerosis," Wiener Klinische Wochenschrift, 86, 80-82
30. Koella, W. P. & Czicman, J. S. (1963). "Influence of serotonin upon optic evoked potentials, EEG, and blood pressure of cat." American Journal of Physiology, 204, 873-880.
31. Krause, K., Cremer-Bartels, G. & Mitoskas, G. (1985). Effects of low magnetic fields on human and avian retina. In Brown, G.M. & Wainwright, S.D. (eds.), The pineal gland: endocrine aspects, pp. 209-215 (Pergamon Press, Oxford).
32. Leino, M. (1984) "6-Methoxy-tetrahydro-beta-carboline and melatonin in the human retina," Experimental Eve Research, 38, 325-330.
33. Lennon, V. A & Carnegie, P. R. (1971). "Immunopharmacological disease: a break in tolerance to receptor sites," Lancet, 2, 630-633.
34. Matthews, W. B. & Glaser, G. H. (1978). Recent advances in clinical neurology, p. 4 (Churchill Livingstone, Edinburgh).
35. Matthews, G & Von Gersdorff, H. (1996). "Calcium dependence of neurotransmitter release," Seminars in Neurosciences, 8, 329-334
36. McCutchen, C. B. & Iragui, V J (1979). Evoked potentials. In Tyler, H R. & Dawson, D.M. (eds ). Current neurology, vol. 2, pp. 391-437. (Houghton Mifflin Professional Publishers, Boston).
37. McDonald, W. I. & Barnes, D, (1989). "Lesson from magnetic resonance imaging in multiple sclerosis," Trends in Neuroscience, 12, 376-379
38. Miguez, J. M., Martin, F. & Aldegunde, M. (1991 a). "Differential effects of pinealectomy on amygdala and hippocampus serotonin metabolism," Journal of Pineal Research, 10, 100-103.
39. Miguez, J. M., Martin, F. & Aldegunde, M. (1991 b). "Long-term pinealectomy alters hypothalamic serotonm metabolism in the rat," Journal of Pineal Research, 11, 75-79.
40. Miguez, J. M., Martin, F. J. & Aldegunde, M. (1994). "Effects of single doses and daily melatonin treatments on serotonin metabolism in rat brain regions," Journal of Pineal Research, 17, 170-176.
41. Olcese, J. M. (1992) Magnetoreception in rodents: involvement of the eyes and the pineal organ may be evidence for a chronobiological substrate In M.C. Moore-Ede, S.S. Campbell & R.J. Reiter (eds.), Electromagnetic fields and circadian rhythmicity, pp. 63-73. (Birkhauser, Boston).
42. Olcese, J., Reuss, S., Stehle, J., Steinlechner, S. & Vollrath, L. (1987). The mammalian pineal and retinae as geomagnetic field detectors. In Trentini, G.P., De Gaetani, C. & Pevet, P. (eds.), Fundamentals and clinics in pineal research, pp. 79-82. (Raven Press, New York).
43. Onofrj, M & Bodis-Wollner, I. (1982). "Dopaminergic deficiency causes delayed visual evoked potentials in rats," Annals of Neurology, 11, 484-490.
44. Onofrj, M., Bazzano, S., Malatesta, G. & Gambi, D. (1990). "Pathophysiology of delayed evoked potentials in multiple sclerosis," Functional Neurology, 5, 301-319.
45. Osol, G. & Schwartz, B (1984). "Melatonin in the human retina," Experimental Eye Research, 38, 213-215.
46. Pang, S. F. & Yew, D. T. (1979). "Pigment aggregation by melatonin in the retinal pigment epithelium and choroid of guinea pigs, Cavia porcellus," Experientia, 35, 231-233.
47. Parkinson, D. & Rando, R. R. (1981). "Evidence for a neurotransmitter role for 5-hydroxytryptamine in chick retina," Journal of Neuroscience, 1, 1211-1217.
48. Persson, H. E. & Sachs, C. (1978). "Provoked visual impairment in multiple sclerosis studied by visual evoked responses," Electroenc ephalography and Clinical Neurophysiology, 44, 664-668.
49. Rao, N. A. (1981). "Chronic experimental allergic optic neuritis," Investigative Ophthalmology and Visual Sciences, 20, 159-172.
50. Reiter, R. J. (1992). Changes in circadian melatonin synthesis in the pineal gland of animals exposed to extremely low frequency electromagnetic radiation: A summary of observations and speculation on their implications. In M C. Moore-Ede, S.S. Campbell & R.J. Reiter (eds.), Electromagnetic fields and circadian rhvthmicity, pp. 13-27. (Birkhauser, Boston).
51. Rinaldi, P., Sutko, M., Mahnke, J H. & Verzeano, M. (1975). "Serotonin in the lateral geniculate body," Physiology & Behavior, 14, 95-102.
52. Rosen, A. D. & Lubowsky, J. (1987). "Magnetic fields influence on central nervous system function," Experimental Neurology, 95, 679-687.
53. Sandyk, R. (1994). "Rapid normalization of visual evoked potentials by picotesla range magnetic Fields in chronic progressive multiple sclerosis," International Journal of Neuroscience, 77, 243-259.
54. Sandyk, R. (1995). "Long term beneficial effects of weak electromagnetic fields in multiple sclerosis," International Journal of Neuroscience, 83, 45-57
55. Sandyk, R. & Derpapas, K. (1993). "Magnetic fields normalize visual and brainstem auditory evoked potentials in multiple sclerosis," International Journal of Neuroscience, 68, 241-253.
56. Sandyk, R. & Derpapas. K. (1994). "The effects of picotesla range magnetic fields on visuospatial functions in multiple sclerosis," International Journal of Neuroscience, 78, 103-109.
57. Semm, P. (1983). "Neurobiological investigations on the magnetic sensitivity of the pineal gland in rodents and pigeons," Comparative Biochemistry and Physiology, 76A, 683-689.
58. Semm, P. (1992). Pineal function in mammals and birds is altered by earth-strength magnetic fields. In M.C. Moore-Ede, S.S. Campbell & R.J. Reiter (eds.), Electromagnetic fields and circadian rhythmicity, pp. 53-62 (Birkhauser. Boston).
59. Sokol, S. (1980), Visual evoked potentials. In M J. Aminoff (ed.), Electrodiagnosis, in clinical neurology, pp. 348-369 (Churchill Livingstone, New York).
60. Sonntnen, V., Riekkinen, P. & Rinne, U. K. (1973). "Acid monoamine metabolites in cerebrospinal fluid in multiple sclerosis," Neurology, 23, 760-763.
61. Symington, G. R., MaCKay, I. R. & Currie, T. T. (1977). "Improvement in multiple sclerosis during prolonged induced hypothermia," Neurology, 27, 302-303.
62. Watson, C. W. (1959). "Effect of lowering of body temperature on the symptoms and signs of multiple sclerosis," New England Journal of Medicine, 261, 1253-1259.
63. Welker, H. A., Semm, P., Willig, R. P., Commentz, J. C., Wiltschko, W. & Vollrath, L. (1983). "Effects of an artificial magnetic field on serotonin N-acetyltransferase activity and melatonin content of the rat pineal gland," Experimental Brain Research, 50, 426-432.
64. Wiechmann, A F. (1986). "Melatonin: parallels in pineal gland and retina," Experimental Eye Research, 42, 507-527.
65. Wiechmann, A. F., Bok, D. & Horwitz, J. (1984). "Immunocytochemical localization of hydroxyindole-Ο-methyltransferase in the mammalian retina," Investigative Ophthalmology and Visual Sciences, 25(suppl), 242
66. Wilson, B. W., Anderson, L. E., Hilton, D. I. & Phillips, R. D. (1981). "Chronic exposure to 60-Hz electric field: effects on pineal function in the rat," Bioelectromagnetics, 2, 371-380.
67. Zeise, M. L. & Semm, P. (1985). "Melatonin lowers excitability of guinea pig hippocampal neurons in vitro," Journal of Comparative Physiology, 157, 23-29.
68. Zisapel, N., Egozi, Y. & Laudon, M. (1982). "Inhibition of dopamine release by melatonin: regional distribution in the rat brain," Brain Research, 246, 161-163.