Alveolar expansion itself but not continuous oxygen supply enhances postmortem preservation of pulmonary grafts

European Journal of Cardio-thoracic Surgery

Volumn 13, Issue 4, 1998, Pages 431-441

  Van Raemdonck, Dirk E M ^a,b   Jannis, Nicole C P ^a   De Leyn, Paul R J ^b   Flameng, Willem J ^a   Lerut, Toni E ^b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Lung ischemia; Lung transplantation; Non heart beating donor; Organ preservation; Pulmonary vascular resistance; Reperfusion

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CADAVER; CONTROLLED STUDY; HEART BEAT; LUNG ALVEOLUS CARBON DIOXIDE TENSION; LUNG PERFUSION; LUNG TRANSPLANTATION; LUNG VASCULAR RESISTANCE; LUNG VENTILATION; NONHUMAN; ORGAN PRESERVATION; OXYGEN SUPPLY; PRIORITY JOURNAL; RABBIT; WEIGHT GAIN;

ANIMALS; GRAFT SURVIVAL; HEMODYNAMIC PROCESSES; LUNG TRANSPLANTATION; ORGAN PRESERVATION; PULMONARY ALVEOLI; RABBITS; REPERFUSION; VASCULAR RESISTANCE;

EID: 0032051752     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1010-7940(98)00046-3     Document Type: Article

References (30)

1. [1] Van Raemdonck D, Roels L, Verleden G, Coosemans W, Michiels E, De Leyn P, Vanhaecke J, Daenen W, Demedts M, Lerut T. Whence the lungs? Assessment of the use of lungs for transplantation from 156 consecutive donors. In: Cooper JD, Weder W, editors. Proceedings of the 3rd International Lung Transplant Symposium (Zurich, June 24-25, 1993), 1993:40.
2. [2] Starnes VA, Barr ML, Cohen RG. Lobar transplantation: Indications, technique and outcome. J Thorac Cardiovasc Surg 1994;108:403-11.
3. [3] Couetil JPA, Tolan MJ, Loulmet DF, Guinvarch A, Chevalier PG, Achkar A, Birmbaum P, Carpentier AF. Pulmonary bipartitioning and lobar transplantation: A new approach to donor organ shortage. J Thorac Cardiovasc Surg 1997;113:529-37.
4. [4] Starnes VA, Barr ML, Cohen RG, Hagen JA, Wells WJ, Horn MV, Schenkel FA. Living-donor lobar lung transplantation experience: Intermediate results. J Thorac Cardiovasc Surg 1996;112:1284-91.
5. [5] D'Alessandro AM, Hoffmann RM, Knechtle SJ, Eckhoff DE, Love RB, Kalayoglu M, Sollinger HW, Beizer FO. Successful extrarenal transplantation from non-heart-beating donors. Transplantation 1995;59:977-82.
6. [6] Love RB, Stringham JC, Chomiak PN, Warner TF, Pellett JR, Mentzer RM. Successful lung transplantation using a non-heart-beating donor. J Heart Lung Transplant 1995;14:88 (abstract).
7. [7] Egan TM, Lambert CJ, Reddick R, Ulicny KS, Keagy BA, Wilcox BR. A strategy to increase the donor pool: Use of cadaver lungs for transplantation. Ann Thorac Surg 1991;52:1113-21.
8. [8] Ulicny KS, Egan TM, Lambert J, Reddick RL, Wilcox BR. Cadaver lung donors: Effect of preharvest ventilation on graft function. Ann Thorac Surg 1993;55:1185-91.
9. [9] Buchanan SA, DeLima NF, Binns OAR, Mauney MC, Cope JT, Langenburg SE, Shockey KS, Bianchi JD, Parekh VI, Tribble CG, Kron IL. Pulmonary function after non-heart-beating lung donation in a survival model. Ann Thorac Surg 1995;60:38-46.
10. [10] Umemori Y, Date H, Uno K, Aoe M, Ando A, Shimizu N. Improved lung function by urokinase infusion in canine lung transplantation using non-heart-beating donors. Ann Thorac Surg 1995;59:1513-8.
11. [11] Roberts CS, D'Armini AM, Egan TM. Canine double-lung transplantation with cadaveric donors. J Thorac Cardiovasc Surg 1996;112:577-83.
12. [12] Hennington MH, D'Armini AM, Lemasters JJ, Egan TM. Cadaver lungs for transplantation. Effect of ventilation with alveolar gas. Transplantation 1996;61:1009-14.
13. [13] Steen S, Ingemansson R, Budrikis A, Bolys R, Roscher R, Sjöberg T. Successful transplantation of lungs topically cooled in the non-heart-beating donor for 6 h. Ann Thorac Surg 1997;63:345-51.
14. [14] Van Raemdonck DEM, Jannis NCP, Rega FRL, De Leyn PRJ, Flameng WJ, Lerut TE. Delay of adenosine triphosphate depletion and hypoxanthine formation in rabbit lung after death. Ann Thorac Surg 1996;62:233-41.
15. [15] Kuang JQ, Van Raemdonck DEM, Jannis NCP, De Leyn PRJ, Verbeken EK, Flameng WJ, Lerut TE. Pulmonary cell death in warm ischemic rabbit lung is related to the postmortem alveolar oxygen reserve. J Heart Lung Transpl (in press).
16. [16] Kuang JQ, Van Raemdonck DEM, Jannis NCP, De Leyn PRJ, Verbeken EK, Flameng WJ, Lerut TE. Pulmonary grafts should be inflated with 100% oxygen prior to hypothermic storage (abstract). J Heart Lung Transplant 1997;16:99.
17. [17] Van Raemdonck DEM, Jannis NCP, Rega FRL, De Leyn PRJ, Flameng WJ, Lerut TE. External cooling of warm ischemic rabbit lungs after death. Ann Thorac Surg 1996;62:331-7.
18. [18] Van Raemdonck DEM, Jannis NCP, Rega FRL, De Leyn PRJ, Flameng WJ, Lerut TE. Extended preservation of ischemic pulmonary graft by postmortem alveolar expansion. Ann Thorac Surg 1997;64:801-8.
19. [19] Puskas JD, Oka T, Mayer E, Wisser W, Downey GP, Slutsky AS, Patterson GA. Hemodilution reduces early reperfusion injury in an ex vivo rabbit lung preservation model. Ann Thorac Surg 1994;57:731-5.
20. [20] Bhabra MS, Hopkinson DN, Shaw TE, Hooper TL. Critical importance of the 1st 10 min of lung graft reperfusion after hypothermic storage. Ann Thorac Surg 1996;61:1631-5.
21. [21] Scheffé HA. A method for judging all contrast in the analysis of variance. Biometrika 1953;40:87-104.
22. [22] Allison RC, Kyle J, Adkins WK, Prasad VR, McCord JM, Taylor AE. Effect of ischemia reperfusion or hypoxia reoxygenation on lung vascular permeability and resistance. J Appl Physiol 1990;69:597-603.
23. [23] Novick RJ, Gehman KE, Ali IS, Lee J. Lung preservation: The importance of endothelial and alveolar type II cell integrity. Ann Thorac Surg 1996;62:302-14.
24. [24] Hopkinson DN, Bhabra MS, Odom NJ, Bridgewater BJM, van Doom CAM, Hooper TL. Controlled pressure reperfusion of rat pulmonary grafts yields improved function after 24 h cold storage in University of Wisconsin solution. J Heart Lung Transplant 1996;15:283-90.
25. [25] Boujoukos AJ, Martich GD, Vega JD, Keenan RJ, Griffith BP. Reperfusion injury in single-lung transplant recipients with pulmonary hypertension and emphysema. J Heart Lung Transplant 1997;16:440-8.
26. [26] Faridy EE. Effect of distension on release of surfactant in excised dogs' lungs. Respir Physiol 1976;27:99-114.
27. [27] Oyarzun MJ, Clements JA. Control of lung surfactant by ventilation, adrenergic mediators, and prostaglandins in the rabbit. Am Rev Respir Dis 1978;117:879-91.
28. [28] Wirtz HRW, Dobbs LG. Calcium mobilization and exocytosis after one mechanical stretch of lung epithelial cells. Science 1990;250:1266-9.
29. [29] Oyarzun MJ, Stevens P, Clements JA. Effect of lung collapse on alveolar surfactant in rabbits subjected to unilateral pneumothorax. Exp Lung Res 1989;15:909-24.
30. 2-ventilated canine pulmonary lobe. J Appl Physiol 1987;63:111-5.