The effect of brain death on cardiovascular function in rats. Part II. The cause of the in vivo haemodynamic changes

Cardiovascular Research

Volumn 38, Issue 1, 1998, Pages 107-115

  Herijgers, Paul ^a   Flameng, Willem ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Adrenergic system; Autonomic nervous system; Brain death; Haemodynamic collapse; Heart rate variability; Rat

Indexed keywords

PHENTOLAMINE;

ADRENERGIC RECEPTOR BLOCKING; ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BRAIN DEATH; CARDIOVASCULAR FUNCTION; COLLAPSE; CONTROLLED STUDY; HEART AFTERLOAD; HEART RATE VARIABILITY; HEMODYNAMICS; NONHUMAN; PRIORITY JOURNAL; RAT; SYMPATHETIC TONE; VAGOTOMY;

ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BLOOD PRESSURE; BRAIN DEATH; HEART; HEART RATE; MALE; PHENTOLAMINE; PROPRANOLOL; RATS; RATS, WISTAR; SYMPATHETIC NERVOUS SYSTEM;

EID: 0032051663     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00284-8     Document Type: Article

References (14)

1. [1] Herijgers P, Borgers M, Flameng W. The effect of brain death on cardiovascular function in rats. Part I. Is the heart damaged?. Cardiovasc Res 1998;38:98-106.
2. [2] Herijgers P, Leunens V, Tjandra-Maga TB, Mubagwa K, Flameng W. Changes in organ perfusion after brain death in the rat and its relation to circulating catecholamines. Transplantation 1996;62:330-335.
3. [3] Galiñanes M, Hearse DJ. Brain-death-induced cardiac contractile function: studies of possible neurohormonal and blood-borne mediators. J Mol Cell Cardiol 1994;26:481-498.
4. [4] Mukherjee A, Haghani Z, Brady J, et al. Differences in myocardial α- and β-adrenergic receptor numbers in different species. Am J Physiol 1983;245:H957-H961.
5. [5] Kopin IJ, Zukowska-Grojec Z, Bayorh MA, Goldstein DS. Estimation of intrasynaptic norepinephrine concentrations at vascular neuroeffector junctions in vivo. Naunyn-Schmiedeberg's Arch Pharmacol 1984;325:298-305.
6. [6] Akselrod S, Elish S, Oz O, Cohen S. Haemodynamic regulation in SHR: investigation by spectral analysis. Am J Physiol 1987;253:H176-H183.
7. [7] Japundzic N, Grichois M-L, Zitoun P, Laude D, Elghozi J-L. Spectral analysis of blood pressure and heart rate in conscious rats: effects of autonomic blockers. J Auton Nerv Syst 1990;30:91-100.
8. [8] Galiñanes M, Hearse DJ. Brain death-induced impairment of cardiac contractile performance can be reversed by explantation and may not preclude the use of hearts for transplantation. Circ Res 1992;71:1213-1219.
9. [9] DeBoer RW, Karemaker JM, Strackee J. Comparing spectra of a series of point events particularly for heart rate variability data. IEEE Trans Biomed Eng 1984;31:384-387.
10. [10] Mason DT. Usefulness and limitations of the rate of rise of intraventricular pressure (dp/dt) in the evaluation of myocardial contractility in man. Am J Cardiol 1969;23:516-527.
11. [11] Gillespie JS, Muir TC. A method of stimulating the complete sympathetic outflow from the spinal cord to blood vessels in the pithed rat. Br J Pharmacol Chemother 1967;30:78-87.
12. [12] Murphy DA, O'Blenes S, Nassar BA, Armour JA. Effects of acutely raising intracranial pressure on cardiac sympathetic efferent neuron function. Cardiovasc Res 1995;30:716-724.
13. [13] Murphy CA, Sloan RP, Myers MM. Pharmacologic responses and spectral analyses of spontaneous fluctuations in heart rate and blood pressure in SHR rats. J Auton Nerv Syst 1991;36:237-250.
14. [14] Charocopos F. The mechanism of beta-adrenergic receptor blockade-induced elevation of arterial blood pressure in rats. Arch Intern Physiol Biochem 1982;90:173-178.