Integrated optical Mach-Zehnder biosensor

Journal of Lightwave Technology

Volumn 16, Issue 4, 1998, Pages 583-592

  Luff, B J ^a,d   Wilkinson, James S ^a,e,f,g   Piehler, Jacob ^b   Hollenbach, Uwe ^c,h,i,j   Ingenhoff, Jan ^b,c,j,k   Fabricius, Norbert ^c,l,m,n,o  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c IOT Entwicklungsgesellschaft F I   (Germany)

^d UNIVERSITY OF SUSSEX   (United Kingdom)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f Hirst Research Centre   (United Kingdom)

^g ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^h UNIVERSITY OF PADERBORN   (Germany)

ⁱ CARL ZEISS SMT AG   (Germany)

^j IOT Integrated Optics Technology   (Germany)

^k ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

^l UNIVERSITY OF DUISBURG ESSEN   (Germany)

^m Fried Krupp Research Institute

ⁿ SCHOTT AG   (Germany)

^o Schott Glass Works ^*

more..

Author keywords

Biomedical transducers; Integrated optics; Interferometry; Waveguide couplers; Waveguides

Indexed keywords

BIOCHEMISTRY; INTEGRATED OPTOELECTRONICS; INTERFEROMETERS; OPTICAL DESIGN; OPTICAL SENSORS; OPTICAL WAVEGUIDES; PROTEINS; TRANSDUCERS; WAVEGUIDE COUPLERS;

BIOMEDICAL TRANSDUCERS; INTEGRATED OPTICAL MACH ZEHNDER BIOSENSORS; MACH ZEHNDER INTERFEROMETERS (MZI);

BIOSENSORS;

EID: 0032051180     PISSN: 07338724     EISSN: None     Source Type: Journal    
DOI: 10.1109/50.664067     Document Type: Article

References (22)

1. R. S. Sethi, "Transducer aspects of biosensors," Biosensors Bioelectron., vol. 9, pp. 243-264, 1994.
2. P. V. Lambeck, "Integrated opto-chemical sensors," Sensors Actuators B, vol. 8, pp. 103-116, 1992.
3. C. Mouvet, R. D. Harris, C. Maciag, J. S. Wilkinson, B. J. Luff, J. Piehler, A. Brecht, G. Gauglitz, R. Abuknesha, and G. Ismail, "Determination of simazine in water samples by waveguide surface plasmon resonance," Analytica Chimica Acta, vol. 338, pp. 109-117, 1997.
4. B. J. Luff, R. D. Harris, J. S. Wilkinson, R. Wilson and D. J. Schiffrin, "Integrated optical directional coupler biosensor," Optics Lett., vol. 21, pp. 618-620, 1996.
5. Ch. Fattinger, H. Koller, D. Schlatter and P. Wehrli, "The difference interferometer: a highly sensitive optical probe for quantification of molecular surface concentration," Biosensors Bioelectron., vol. 8, pp. 99-107, 1993.
6. D. Clerc and W. Lukosz, "Integrated optical output grating coupler as refractometer and (bio-)chemical sensor," Sensors Actuators B, vol. 11, pp. 461-465, 1993.
7. G. Gauglitz and J. Ingenhoff, "Design of new integrated optical substrates for immuno-analytical applications," Fresenius J. Anal. Chem., vol. 349, pp. 355-359, 1994.
8. R. G. Heideman, R. P. H. Kooyman, and J. Greve, "Performance of a highly sensitive optical waveguide Mach-Zehnder interferometer immunosensor," Sensors Actuators B, vol. 10, pp. 209-217, 1993.
9. L. Ross, "Ion-exchanged glass waveguide sensors," SPIE Proc., vol. CR53, 1994.
10. J. Rickert, A. Brecht, and W. Göpel, "Quartz crystal microbalances for quantitative biosensing and characterizing protein multilayers," submitted to Biosensors Bioelectron., vol. 12, pp. 567-575, 1997.
11. K. Spaeth, A. Brecht, and G. Gauglitz, "Studies on the biotin-avidin multilayer adsorption by spectroscopic ellipsometry," J. Colloids Interface Sci., vol. 196, pp. 128-135, 1997.
12. B. J. Luff, R. D. Harris, I. S. Wilkinson, J. Piehler, A. Brecht, G. Gauglitz, and U. Hollenbach, "Integrated optical sensors for pesticide analysis," in Applications of Photonic Technology 2, G. A. Lampropoulos and R. A. Lessard, Eds. New York: Plenum, 1997, pp. 909-914.
13. A. Yariv, Optical Electronics. Philadelphia, PA: Saunders, 1991.
14. S. L. Chuang, "Application of the strongly coupled mode theory to integrated optical devices," IEEE J. Quantum Electron., vol. QE-23, pp. 499-509, 1987.
15. A. Hardy and W. Streifer, "Coupled mode solutions of multiwaveguide systems," IEEE J. Quantum Electron., vol. QE-22, pp. 528-534, 1986.
16. S. L. Chuang, "A coupled-mode theory for multiwaveguide systems satisfying the reciprocity theorem and power conservation," J. Lightwave Technol., vol. LT-5, pp. 174-183, 1987.
17. R. Fuest, N. Fabricius, U. Hollenbach and B. Wolf, "Interferometric displacement sensor realized with a planar 3 x 3 directional coupler in glass," in Proc. SPIE Symp. OE/Fibers'92, Boston, MA, 1992.
18. J. Ruzicka and E. H. Hansen, Flow Injection Analysis. New York: Wiley, 1987.
19. M. Berger, A. Deger, and J. Maler, "Verfahren zur Herstellung einer Festphasenmatrix," European Pat. 0 331 127 B1, 1993.
20. P. Yeh, Optical Waves in Layered Media. New York: Wiley, 1988.
21. J. A. DeFeijter J. Benjamins, and F. A. Veer, "Ellipsometry as a tool to study the adsorption behavior of synthetic and biopolymers at the air-waler interface," Biopolymers, vol. 17 pp. 1759-1772, 1978.
22. W. Huber, R. Barner, Ch. Fattinger, J. Hübscher, H. Koller, F. Müller, and D. Schlatter, "Direct optical immunosensing (sensitivity and selectivity)," Sensors Actuators B, vol. 6 pp. 122-126, 1992.