Pathogenesis of Porcine Actinobacillus Pleuropneumonia: Part I. Effects of Surface Components of Actinobacillus pleuropneumoniae in Vitro and in Vivo

Canadian Journal of Veterinary Research

Volumn 62, Issue 2, 1998, Pages 93-101

  Huang, Hongsheng ^a,c   Potter, Andrew A ^b   Campos, Manuel ^d   Leighton, Frederick A ^a   Willson, Philip J ^b   Yates, William D G ^c  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c CANADIAN FOOD INSPECTION AGENCY   (Canada)

^d Pzifer Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN;

ACTINOBACILLUS PLEUROPNEUMONIAE; ANIMAL; ANIMAL DISEASE; ARTICLE; BACTERIAL INFECTION; BONE MARROW CELL; CELL CULTURE; CELL MEMBRANE; CELL SURVIVAL; CHEMISTRY; CLASSIFICATION; DRUG EFFECT; IMMUNOLOGY; LUNG; LUNG ALVEOLUS MACROPHAGE; PATHOGENICITY; PATHOLOGY; PATHOPHYSIOLOGY; SWINE; SWINE DISEASE; VIRULENCE;

ACTINOBACILLUS INFECTIONS; ACTINOBACILLUS PLEUROPNEUMONIAE; ANIMALS; BACTERIAL PROTEINS; BONE MARROW CELLS; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES, ALVEOLAR; MEMBRANE PROTEINS; SWINE; SWINE DISEASES; VIRULENCE;

EID: 0032044433     PISSN: 08309000     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. SHOPE RE. Porcine contagious pleuropneumonia. I. Experimental transmission, etiology and pathology J Exp Med 1964; 119: 357-368.
2. SEBUNYA TNK, SAUNDERS JR. Haemophilus pleuropneumoniae infection in swine: A review. J Am Vet Med Assoc 1983; 182: 1331-1337.
3. ROSENDAL S, MITCHELL WR, WILSON WR, ZAMAN MR. Hemophilias pleuropneumonia. Lung lesions induced by sonicated and sterile culture supernatant. Proc Int Pig Vet Soc 1980: 221.
4. FREY J, BOSSE JT, CHANG Y-F, CULLEN MJ, FENWICK B, GERLACH GF, GYGI D, HAESEBROUCK F, INZANA R, JANSEN R, KAMP EM, MACDONALD J, MACINNES JI, MITTAL KR, NICOLET J, RYCROFT AN, SEGERS RPAM, SMITS MA, STENBEAK E, STRUCK DK, VAN DEN BOSCH JF, WILLSON PJ, YOUNG R. Actinobacillus pleuropneumoniae RTX-toxins: Uniform designation of hemolysins. cytolysins. pleurotoxin and their genes. J Gen Microbiol 1993; 139: 1723-1728.
5. 2+. Infect Immun 1988; 56: 2570-2575.
6. KAMP EM, POPMA JK, ANAKOTTA J, SMITS MA. Identification of hemolytic and cytotoxic proteins of Actinobacillus pleuropneumoniae by use of monoclonal antibodies. Infect Immun 1991; 59: 3079-3085.
7. RYCROFT AN, WILLIAMS D, CULLEN JM, MACDONALD J. The cytotoxin of Actinobacillus pleuropneumoniae (pleurotoxin) is distinct from the haemolysin and is associated with 120 kDa polypeptide. J Gen Microbiol 1991; 137: 561-568.
8. SMITS M, KAMP E, BRIAIRE J, JANSEN R, VAN LEENGOED L, VAN DIJK J. Induction of pneumonic lesions by recombinant cytolysms of Actinobacillus pleuropneumoniae. Proc Int Pig Vet Soc 1992: 187.
9. KILIAN M, MESTECKY J, SCHROHENLOHER RE. Pathogenic species of genus Haemophilus and Streptococcus pneumonias produce immunoglobulin A1 protease. Infect Immun 1979; 26: 143-149.
10. BEAUDET R, MCSWEEN G, BISAILLON JG. Production and purification of a low molecular weight haemolysin produced by Actinobacillus pleuropneumoniae serotype 1. Res Vet Sci 1993; 54. 45-51.
11. NEGRETE-ABASCAL E, TENORIO VR, SERRANO JJ, GARCIA CC. DE LA GARZA M. Secreted proteases from Actinobacillus pleuropneumoniae serotype 1 degrade porcine gelatin, hemoglobin and immunoglobulin A. Can J Vet Res 1994; 58: 83-86.
12. SEREBRIN S, ROSENDAL S, VALDIVIESO-GARCIA A, LITTLE PB. Endothelial cytotoxicity of Actinobacillus pleuropneumoniae. Res Vet Sci 1991; 50: 18-22.
13. BERTRAM TA. Pathobiology of acute pulmonary lesions in swine infected with Haemophilus (Adinobacillus) pleuropneumoniae. Can Vet J 1988; 29: 574-577.
14. BERTRAM TA. Actinobacillus pleuropneumoniae. Molecular aspects of virulence and pulmonary injury. Can J Vet Res 1990; 54: S53-S56.
15. HUANG HS, POTTER AA, CAMPOS M, LEIGHTON FA, WILLSON P, HAINES D, YATES WDG. Pathogenesis of porcine Actinobacillus pleuropneumonia: Part II. Roles of Proinflammatory cytokines (submitted to Can J Vet Res).
16. MACINNES JL ROSENDAL S. Prevention and control of Actinobacillus (Haemophilus) pleuropneumoniae infection in swine: A review. Can Vet J 1988; 29: 572-574.
17. FEDORKA-CRAY PJ, ANDERSON GA, CRAY WC Jr. GRAY JT, BREISCH SA. Actinobacillus (Haemophilus) pleuropneumoniae. Part II. Virulence factors, immunity, and vaccines, Compend Contin Educ Pract Vet 1994; 16: 117-125
18. NIELSEN R. Haemophilus pleuropneumoniae: Serotypes. pathogenicity, and cross immunity. Nord Vet Med 1979; 31: 407-413.
19. FEDORKA-CRAY PJ, STINE DL, GREENWALD JM, GRAY JT, HUETHER MJ, ANDERSON GA. The importance of secreted virulence factors in Adinobacillus pleuropneumoniae bacterin preparation: A comparison. Vet Microbiol 1993; 37: 85-100.
20. WILLSON PJ, ROSSI-CAMPOS A, POTTER AA. Tissue reaction and immunity in swine immunized with Actinobacillus pleuropneumoniae vaccines. Can J Vet Res 1995; 59: 299-305.
21. BIELEFELDT OHMANN H, MCDOUGALL L, POTTER A. Secondary in vitro B lymphocyte (antibody) response to microbial antigens: Use in appraisal of vaccine immunogenicity and cytokine immunoregulation. Vaccine 1991; 9: 171-176.
22. WILLSON PJ, OSBORNE AD. Comparison of common antibiotic therapies for Haemophilus pleuropneumoniae in pigs. Can Vet J 1985; 26: 312-316.
23. ANDERSON C, POTTER A, GERLACH G. 1991. Isolation and Molecular characterization of spontaneously occurring cytolysin-negative mutants of Actmobacillus pleuropneumoniae serotype 7. Infect Immun 1991; 59: 4110-4116.
24. GERLACH GF, ANDERSON C, POTTER A, KLASHINSKY A, WILLSON PJ. Cloning and expression of a transferrin-binding protein from Actinobacilius pleuropneumoniae. Infect Immun 1992; 60: 892-898.
25. ALTMAN E, BRISSON JR, PERRY M. Structure of the O-chain of the lipopolysaccharide of Haemophilus pleuropneumoniae serotype 1. Biochem Cell Bio 1986; 64: 1317-1325.
26. STOSCHECK CM. Quantitation of Proleins. In: Deutscher MP. ed. Methods in Enzymology: Guide to Protein Purification. New York: Academic Press, Inc, 1990: 57-60.
27. CANADIAN COUNCIL ON ANIMAL CARE. Guide to the Care and Use of Experimental Animals. 2 vols. Ottawa, Ontario. CCAC, 1980-1984.
28. WILLSON PJ, SCHIPPER C, MORGAN ED. The use of an enzyme-linked immunosorbent assay for diagnosis of Actinobacillus pleuropneumoniae infection in pigs. Can Vet J 1988; 29: 583-585.
29. FIELD TR, WILLIAMS MR, BUNCH KJ. An improved method for the isolation of a neutrophil-rich fraction from porcine blood. Br Vet J 1985; 141: 355-361.
30. CAMPOS M, ROSSI CR. Inability to detect a K cell in bovine peripheral blood leukocytes. Vet Immunol Immunopathol 1985; 8: 351-362.
31. KOSKI IR, POPLACK DG, BLAESE RM. A non-specific esterase stain for the identification of monocytes, and macrophages. In: Bloom BR, David JR, eds. In Vitro Methods of Cell-Mediated and Tumor Immunity. New York: Academic Press, Inc. 1976: 359.
32. BERGMEYER HU, GRAVEHN K. Methods of enzymatic analysis, New York: Academic Press, Inc. 1978: 574-579.
33. HANSEN MB, NIELSEN SE, BERG K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Meth 1989; 119: 203-210.
34. ROSSI-CAMPOS A, ANDERSON C, GERLACH G, KLASHINKY S, POTTER A, WILLSON PJ. Immunization of pigs against Actinobacillus pleuropneumoniae with two recombinant protein preparations. Vaccine 1992; 10: 512-518.
35. HUANG HS. A study of the pathogenesis of acute Actinobacillus pleuropneumoniae infection in swine (PhD dissertation). Saskatoon. University of Saskatchewan, 1995: 204p.
36. BENDIXEN P, SHEWEN PE, ROSENDAL S, WILKIE BN. Toxicity of Haemophilus pleuropneumoniae for porcine lung macrophages, peripheral blood monocytes, and testicular cells. Infect Immun 1981; 33: 673-676.
37. VAN LEENGOED LA, KAMP EM, POL JMA. Toxicity of Haemophilus pleuropneumoniae to porcine lung macrophases. Vet Microbiol 1989; 19: 337-329.
38. DA VIS WB, BARSOUM IS, RAMWELL PW, YEAGER H. Human alveolar macrophages: Effects of endotoxin in vitro. Infect Immun 1980; 30: 753-758.
39. OHTA H, HARA H, FUKUI K, KURIHARA H, MURAYAMA Y, KATO K. Association of Actinobacillus actinomycetemcomitans leukotoxin with nucleic acids on the bacterial cell surface. Infect Immun 1993; 61: 4878-4884.
40. WELCH RA. Pore-forming cytolysins of Gram-negative bacteria. Mol Microbiol 1991; 5: 521-528.