메뉴 건너뛰기




Volumn 60, Issue 4, 1998, Pages 513-517

Prevention of Orotic-Acid-Induced Fatty Liver in Male Rats by Dehydroepiandrosterone and/or Phenobarbital

Author keywords

Dehydroepiandrosterone; Fatty liver; Orotic acid; Peroxisome proliferator; Phenobarbital

Indexed keywords

RODENTIA;

EID: 0032044375     PISSN: 09167250     EISSN: None     Source Type: Journal    
DOI: 10.1292/jvms.60.513     Document Type: Article
Times cited : (7)

References (32)
  • 1
    • 0027479757 scopus 로고
    • Is dehydroepiandrosterone an antiobesity agent?
    • Berdanier. C. D., Parente. J. A. and McIntosh, M. K. 1993. Is dehydroepiandrosterone an antiobesity agent? FASEB J. 7. 414-419.
    • (1993) FASEB J. , vol.7 , pp. 414-419
    • Berdanier, C.D.1    Parente, J.A.2    McIntosh, M.K.3
  • 2
    • 0025959199 scopus 로고
    • The antiobesity effect of dehydroepiandrosterone in rats
    • Cleary, M. P. 1991. The antiobesity effect of dehydroepiandrosterone in rats. Proc. Soc. Exp. Biol. Med. 196: 8-16.
    • (1991) Proc. Soc. Exp. Biol. Med. , vol.196 , pp. 8-16
    • Cleary, M.P.1
  • 3
    • 0020958938 scopus 로고
    • Effect of dehydroepiandrosterone on body weight and food intake in rats
    • Cleary, M. P., Shepherd, A., Zisk, J. and Schwartz, A. 1983. Effect of dehydroepiandrosterone on body weight and food intake in rats. Nutr. Behav. 1: 127-136.
    • (1983) Nutr. Behav. , vol.1 , pp. 127-136
    • Cleary, M.P.1    Shepherd, A.2    Zisk, J.3    Schwartz, A.4
  • 4
    • 0026919394 scopus 로고
    • Influence of single and concurrent clofibrate and phenobarbital administration on cytochrome P450-dependent mixed funciion oxidase activities and peroxisome proliferation in male rat liver
    • Close, I., Shackleton, G., Goldfarb, P. S. and Gibson, G. G. 1992. Influence of single and concurrent clofibrate and phenobarbital administration on cytochrome P450-dependent mixed funciion oxidase activities and peroxisome proliferation in male rat liver. J. Biochem. Toxicol. 7: 193-198.
    • (1992) J. Biochem. Toxicol. , vol.7 , pp. 193-198
    • Close, I.1    Shackleton, G.2    Goldfarb, P.S.3    Gibson, G.G.4
  • 5
    • 0021334185 scopus 로고
    • Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice
    • Coleman, D. L., Schwizer, R. W. and Leiter, E. H. 1984. Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice. Diabetes 33: 26-32.
    • (1984) Diabetes , vol.33 , pp. 26-32
    • Coleman, D.L.1    Schwizer, R.W.2    Leiter, E.H.3
  • 6
    • 0015508547 scopus 로고
    • A comparison of hypolipidemic drugs in the prevention of an orotic acid fatty liver
    • Elwood, J. C., Richert, D. A. and Westerfeld, W. W. 1972. A comparison of hypolipidemic drugs in the prevention of an orotic acid fatty liver. Biochem. Pharmac. 21: 1127-1134.
    • (1972) Biochem. Pharmac. , vol.21 , pp. 1127-1134
    • Elwood, J.C.1    Richert, D.A.2    Westerfeld, W.W.3
  • 7
    • 0025923629 scopus 로고
    • Effect of the perosixome proliferator LY171883 on triglyceride accumulation in rats fed a fat-free diet
    • Foxworthy, P. S. and Eacho, P. I. 1991. Effect of the perosixome proliferator LY171883 on triglyceride accumulation in rats fed a fat-free diet. Biochem. Pharmac. 42: 1487-1491.
    • (1991) Biochem. Pharmac. , vol.42 , pp. 1487-1491
    • Foxworthy, P.S.1    Eacho, P.I.2
  • 8
    • 0025116537 scopus 로고
    • Dietary orotic acid accentuates the hepatic response to phenobarbital in rats
    • Haines, D. S. M., Wu. M. and Tokmakjian, S. D. 1990. Dietary orotic acid accentuates the hepatic response to phenobarbital in rats. Biochem. Cell Biol. 68: 1146-1149.
    • (1990) Biochem. Cell Biol. , vol.68 , pp. 1146-1149
    • Haines, D.S.M.1    Wu, M.2    Tokmakjian, S.D.3
  • 9
    • 0011941282 scopus 로고
    • Ultrastructural study of magnesium dependent adenosine triphosphatase (Mg-ATPase) activity in rat liver peroxsomes after administration of aspirin and clofibrate
    • Hakoi, K., Irimura, K. and Makita, T. 1993. Ultrastructural study of magnesium dependent adenosine triphosphatase (Mg-ATPase) activity in rat liver peroxsomes after administration of aspirin and clofibrate. Med. Electron Micrse. 26: 161-168.
    • (1993) Med. Electron Micrse. , vol.26 , pp. 161-168
    • Hakoi, K.1    Irimura, K.2    Makita, T.3
  • 10
    • 0025043758 scopus 로고
    • Hypolipidemic activity in rodents of phenobarbital and related derivatives
    • Hall, I. H., Patrick, M. A. and Maguire, J. H. 1990. Hypolipidemic activity in rodents of phenobarbital and related derivatives. Arch. Pharm. 323: 579-586.
    • (1990) Arch. Pharm. , vol.323 , pp. 579-586
    • Hall, I.H.1    Patrick, M.A.2    Maguire, J.H.3
  • 11
    • 2542620276 scopus 로고
    • Pathogenesis of orotic acid-induced fatty change in the rat liver
    • Jatlow, P., Adams, W. R. and Handschumacher, R. E. 1965. Pathogenesis of orotic acid-induced fatty change in the rat liver. Am. J. Pathol. 47: 125-145.
    • (1965) Am. J. Pathol. , vol.47 , pp. 125-145
    • Jatlow, P.1    Adams, W.R.2    Handschumacher, R.E.3
  • 12
    • 0031014131 scopus 로고    scopus 로고
    • Induction of peroxisomal enzymes in rat liver by dehydroepiandrosterone sulfate
    • Khan, S. A. and Nyce, J. W. 1997. Induction of peroxisomal enzymes in rat liver by dehydroepiandrosterone sulfate. Cancer Lett. 111: 187-190.
    • (1997) Cancer Lett. , vol.111 , pp. 187-190
    • Khan, S.A.1    Nyce, J.W.2
  • 13
    • 0029561363 scopus 로고
    • Effects of withdrawal of bezafibrate on fine structures of hepatic peroxisomes of the male rat
    • Kondo, K. and Makita, T. 1995. Effects of withdrawal of bezafibrate on fine structures of hepatic peroxisomes of the male rat. Biomed. Res. 16: 387-398.
    • (1995) Biomed. Res. , vol.16 , pp. 387-398
    • Kondo, K.1    Makita, T.2
  • 14
  • 15
    • 0023633151 scopus 로고
    • The effect of dehydroepiandrosterone acetate on liver peroxisomal enzyme activities of male and female rats
    • Leighton, B., Tagliaferro, A. R. and Newsholme, E. A. 1987. The effect of dehydroepiandrosterone acetate on liver peroxisomal enzyme activities of male and female rats. J. Nutr. 117: 1287-1290.
    • (1987) J. Nutr. , vol.117 , pp. 1287-1290
    • Leighton, B.1    Tagliaferro, A.R.2    Newsholme, E.A.3
  • 16
    • 0025140914 scopus 로고
    • Effects of dehydroepiandrosterone treatment in rats with diet-induced obesity
    • Mohan, P. F., Ihnen, J. S., Levin, B. E. and Cleary, M. P. 1990. Effects of dehydroepiandrosterone treatment in rats with diet-induced obesity. J. Nutr. 120: 1103-1114.
    • (1990) J. Nutr. , vol.120 , pp. 1103-1114
    • Mohan, P.F.1    Ihnen, J.S.2    Levin, B.E.3    Cleary, M.P.4
  • 17
    • 0027212575 scopus 로고
    • Inhibition of macrophage Superoxide generation by dehydroepiandrosterone
    • Mohan, P. F. and Jacobson, M. S 1993. Inhibition of macrophage Superoxide generation by dehydroepiandrosterone. Am. J. Med. Sci. 306: 10-15.
    • (1993) Am. J. Med. Sci. , vol.306 , pp. 10-15
    • Mohan, P.F.1    Jacobson, M.S.2
  • 18
    • 0023022512 scopus 로고
    • Ultrastructural and enzyme histochemical studies in orotic acid-induced fatty liver
    • Murakoshi, M., Misawa, M. and Watanabe, K. 1986. Ultrastructural and enzyme histochemical studies in orotic acid-induced fatty liver. Tokai J. Exp. Clin. Med. 11: 39-45.
    • (1986) Tokai J. Exp. Clin. Med. , vol.11 , pp. 39-45
    • Murakoshi, M.1    Misawa, M.2    Watanabe, K.3
  • 19
    • 0017361033 scopus 로고
    • Reversal of orotic acid-induced fatty liver in rats by clofibrate
    • Novikoff, P. M. and Edelstein, D. 1977. Reversal of orotic acid-induced fatty liver in rats by clofibrate. Lab. Invest. 36: 215-231.
    • (1977) Lab. Invest. , vol.36 , pp. 215-231
    • Novikoff, P.M.1    Edelstein, D.2
  • 20
    • 0014588248 scopus 로고
    • Visualization of peroxisomes (microbodies) and mitochondria with diaminobenzidine
    • Novikoff, A. B. and Goldfisher, S. 1969. Visualization of peroxisomes (microbodies) and mitochondria with diaminobenzidine. Acta Histochem. Cytochem. 17: 675-680.
    • (1969) Acta Histochem. Cytochem. , vol.17 , pp. 675-680
    • Novikoff, A.B.1    Goldfisher, S.2
  • 21
    • 0016169552 scopus 로고
    • Production and prevention of fatty liver in rats fed clofibrate and orotic acid diets containing sucrose
    • Novikoff, P. M., Roheim, P. S., Novikoff, A. B. and Edelstein, D. 1974. Production and prevention of fatty liver in rats fed clofibrate and orotic acid diets containing sucrose. Lab. Invest. 30: 732-750.
    • (1974) Lab. Invest. , vol.30 , pp. 732-750
    • Novikoff, P.M.1    Roheim, P.S.2    Novikoff, A.B.3    Edelstein, D.4
  • 22
    • 0028450833 scopus 로고
    • Effects of oral administration of bezafibrate on peroxisomes and carnitine acetyl-transferase in rat hepatocytes
    • Ohue, M. and Makita, T. 1994. Effects of oral administration of bezafibrate on peroxisomes and carnitine acetyl-transferase in rat hepatocytes. J. Vet. Med. Sci. 56: 541-546.
    • (1994) J. Vet. Med. Sci. , vol.56 , pp. 541-546
    • Ohue, M.1    Makita, T.2
  • 23
    • 0026581368 scopus 로고
    • Differences in the response of Sprague-Dawley and Lewis rats to bezafibrate: The hypolipidemic effect and the induction of peroxisomal enzymes
    • Pill, J., Volkl, A., Harting, F. and Fahimi, H. D. 1992. Differences in the response of Sprague-Dawley and Lewis rats to bezafibrate: the hypolipidemic effect and the induction of peroxisomal enzymes. Arch. Toxicol. 66: 327-333.
    • (1992) Arch. Toxicol. , vol.66 , pp. 327-333
    • Pill, J.1    Volkl, A.2    Harting, F.3    Fahimi, H.D.4
  • 24
    • 0026531580 scopus 로고
    • Dehydroepiandrosterone-induced peroxisome proliferation in the rat liver
    • Rao, M. S., Musunuri, S. and Reddy, J. K. 1992. Dehydroepiandrosterone-induced peroxisome proliferation in the rat liver. Pathobiology 60: 82-86.
    • (1992) Pathobiology , vol.60 , pp. 82-86
    • Rao, M.S.1    Musunuri, S.2    Reddy, J.K.3
  • 25
    • 0027971913 scopus 로고
    • Dehydroepiandrosterone-induced peroxisome proliferation in the rat: Evaluation of sex differences
    • Rao, M. S., Reid, B., Ide, H., Subbarao, V. and Reddy, J. K. 1994. Dehydroepiandrosterone-induced peroxisome proliferation in the rat: evaluation of sex differences. Proc. Soc. Exp. Biol. Med. 207: 186-190.
    • (1994) Proc. Soc. Exp. Biol. Med. , vol.207 , pp. 186-190
    • Rao, M.S.1    Reid, B.2    Ide, H.3    Subbarao, V.4    Reddy, J.K.5
  • 26
    • 0017744318 scopus 로고
    • Accumulation of nascent lipoproteins in rat hepatic Golgi during induction of fatty liver by orotic acid
    • Sabesin, S. M., Frase, S. and Ragland, J. B. 1977. Accumulation of nascent lipoproteins in rat hepatic Golgi during induction of fatty liver by orotic acid. Lab. Invest. 37: 127-135.
    • (1977) Lab. Invest. , vol.37 , pp. 127-135
    • Sabesin, S.M.1    Frase, S.2    Ragland, J.B.3
  • 27
    • 0002698243 scopus 로고
    • Morphological changes in the hepatocyte peroxisomes by age in mice administered with an anti-hyperlipidemic agent, clofibrte
    • Takebe, H. 1992. Morphological changes in the hepatocyte peroxisomes by age in mice administered with an anti-hyperlipidemic agent, clofibrte. J. Clin. Electron Microse. 25: 95-110.
    • (1992) J. Clin. Electron Microse. , vol.25 , pp. 95-110
    • Takebe, H.1
  • 29
    • 0008756785 scopus 로고
    • An orotic acid-induced, adeninereversed inhibition of hepatic lipoprotein secretion in the rat
    • Windmueller, H. G. 1964. An orotic acid-induced, adeninereversed inhibition of hepatic lipoprotein secretion in the rat. J. Biol. Chem. 239: 530-537
    • (1964) J. Biol. Chem. , vol.239 , pp. 530-537
    • Windmueller, H.G.1
  • 30
    • 0014198227 scopus 로고
    • Total inhibition of hepatic β-lipoprotein production in the rat by orotic acid
    • Windmueller, H. G. and Levy, R. I. 1967. Total inhibition of hepatic β-lipoprotein production in the rat by orotic acid. J. Biol. Chem. 242: 2246-2254.
    • (1967) J. Biol. Chem. , vol.242 , pp. 2246-2254
    • Windmueller, H.G.1    Levy, R.I.2
  • 31
    • 0025752416 scopus 로고
    • Characteristics of dehydroepiandrosterone as a peroxisome proliferator
    • Yamada, J., Sakuma, M., Ikeda, T., Fukuda, K. and Suga, T. 1991. Characteristics of dehydroepiandrosterone as a peroxisome proliferator. Biochim. Biophys. Acta 1092: 233-243.
    • (1991) Biochim. Biophys. Acta , vol.1092 , pp. 233-243
    • Yamada, J.1    Sakuma, M.2    Ikeda, T.3    Fukuda, K.4    Suga, T.5
  • 32
    • 0026775831 scopus 로고
    • Induction of peroxisomal β-oxidation enzymes by dehydroepiandrosterone and its sulfate in primary cultures of rat hepatocytes
    • Yamada, J., Sakuma, M. and Suga, T. 1992. Induction of peroxisomal β-oxidation enzymes by dehydroepiandrosterone and its sulfate in primary cultures of rat hepatocytes. Biochim. Biophys. Acta 1160; 231-236.
    • (1992) Biochim. Biophys. Acta , vol.1160 , pp. 231-236
    • Yamada, J.1    Sakuma, M.2    Suga, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.