Ontogenetic Changes in Responsiveness to Benzodiazepine Receptor Ligands on Ultrasonic Vocalizations in Rat Pups

Experimental Animals

Volumn 47, Issue 2, 1998, Pages 89-96

  Naito, Hiroyuki ^a   Nakamura, Amane ^a   Inoue, Maki ^a  

^a AZABU UNIVERSITY   (Japan)

Author keywords

Anxiety; Diazepam; Rat pups; Type 1 benzodiazepine receptor agonist; Ultrasonic vocalization

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANXIOLYTIC AGENT; DIAZEPAM;

ANIMAL; ARTICLE; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; RAT; SEPARATION ANXIETY; ULTRASOUND; VOCALIZATION;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY, SEPARATION; DIAZEPAM; RATS; RECEPTORS, GABA-A; ULTRASONICS; VOCALIZATION, ANIMAL;

EID: 0032042649     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.47.89     Document Type: Article

References (39)

1. Allin, J.T. and Banks, E.M. 1972. Functional aspects of ultrasound production by infant albino rats (Rattus norvegicus). Anim. Behav. 20: 175-185.
2. Bell, R.W. 1979. Ultrasonic control of maternal behavior: Developmental implications. Amer. Zool. 19: 413-418.
3. Braestrup, C. and Nielsen, M. 1978. Ontogenetic development of benzodiazepine receptors in the rat brain. Brain Res. 147: 170-173.
4. Brown, A.M. 1976. Ultrasound and communication in rodents. Comp. Biochem. Physiol. 53A: 313-317.
5. Carden, S.E. and Hofer, M.A. 1990. Independence of benzodiazepine and opiate action in the suppression of isolation distress in the rat. Behav. Neurosci. 104: 160-166.
6. Cuomo, V., Cagiano, R., De Salvia, M.A., Maselli, M.A., Renna, G., and Racagni, G. 1988. Ultrasonic vocalization in response to unavoidable aversive stimuli in rats: Effects of benzodiazepines. Life Sci. 43: 485-491.
7. De Vry, J., Benz, U., Schreiber, R., and Traber, J. 1993. Shock-induced ultrasonic vocalization in young adult rats: A model for testing putative anti-anxiety drugs. Eur. J. Pharmacol. 249: 331-339.
8. File, S.E. and Wilks, L.J. 1986. The effects of benzodiazepines in newborn rats suggest a function for type 2 receptors. Pharmacol. Biochem. Behav. 25: 1145-1148.
9. Gardner, C.R. 1985a. Distress vocalization in rat pups: A simple screening method for anxiolytic drugs. J. Pharmacol. Methods 14: 181-187.
10. Gardner, C.R. 1985b. Inhibition of ultrasonic distress vocalization in rat pups by chlordiazepoxide and diazepam. Drug Develop. Res. 5: 185-193.
11. Gardner, C.R. and Budhrum, P. 1987. Effects of agents which interact with central benzodiazepine binding sites on stress-induced ultrasounds in rat pups. Eur. J. Pharmacol. 134: 275-283.
12. Hofer, M.A. and Shair, H.N. 1987. Isolation distress in two-week-old rats: Influence of home cage, social companion, and prior experience with littermates. Devel. Psychobiol. 20: 465-476.
13. Insel, T.R., Hill, J.L., and Mayor, R.B. 1986. Rat pup ultrasonic isolation calls: Possible mediation by the benzodiazepine receptor complex. Pharmacol. Biochem. Behav. 24: 1263-1267.
14. Johnston, A.L., File, S.E., Dingemanse, J., and Aranko, K. 1989. Diazepam reverses the effects of pentylenetetrazole in rat pups by acting at type 2 benzodiazepine receptors. Pharmacol. Biochem. Behav. 32: 823-825.
15. Kaltwasser, M.T. 1990. Startle-inducing acoustic stimuli evoke ultrasonic vocalization in the rat. Physiol. Behav. 48: 13-17.
16. Kaltwasser, M.T. 1991. Acoustic startle induced ultrasonic vocalization in the rat: A novel animal model of anxiety. Behav. Brain Res. 43: 133-137.
17. Klepner, C.A., Lippa, A.S., Benson, D.I., Sano, M.C., and Beer, B. 1979. Resolution of two biochemically and pharmacologically distinct benzodiazepine receptors. Pharmacol. Biochem. Behav. 11: 457-462.
18. Lippa, A.S., Beer, B., Sano, M.C., Vogel, R.A., and Meyerson, L.R. 1981. Differential ontogeny of type 1 and type 2 benzodiazepine receptors. Life Sci. 28: 2343-2347.
19. Miczek, K.A., Tomatzky, W., and Vivian, J. 1991. Ethology and neuropharmacology: Rodent ultrasounds. pp. 409-427. In: Animal Models in Psychopharmacology (Olivier, B., Mos, J., and Slangen, J.L. eds.), Birkhauser Verlag, Basel.
20. Molewijk, H.E., Van der Poel, A.M., Mos, J., Van der Heyden, J.A.M., and Olivier, B. 1995. Conditioned ultrasonic distress vocalization in adult male rats as a behavioural paradigm for screening antipanic drugs. Psychopharmacology 117: 32-40.
21. Mos, J. and Olivier, B. 1989. Ultrasonic vocalization by rat pups as an animal model for anxiolytic activity: Effects of serotonergic drugs. pp. 361-366. In: Behavioural Pharmacology of 5-HT (Bevan, P., Cools, A.R., and Archer, T. eds.), Lawrence Erlbaum Associates, Hillsdale, NJ.
22. Naito, H. and Tonoue, T. 1987. Sex differences in ultrasound distress call by rat pups. Behav. Brain Res. 25: 13-21.
23. Naito, H., Arishima, K., and Tonoue, T. 1995. Neonatal damage to neocortex abolishes the anxiolytic action of diazepam in adult rats. Eur. J. Pharmacol. 272: 261-268.
24. Noirot, E. 1968. Ultrasounds in young rodents. II. Changes with age in albino rats. Anim. Behav. 16: 129-134.
25. Nyby, J. and Whitney, G. 1978. Ultrasonic communication of adult myomorph rodents. Neurosci. Biobehav. Rev. 2: 1-14.
26. Okon, E.E. 1972. Factors affecting ultrasound production in infant rodents. J. Zool. London. 168: 139-148.
27. Olivier, B., Molewijk, E., Van Oorschot, R., Van der Poel, G., Zethof, T., Van der Heyden, J., and Mos, J. 1994. New animal models of anxiety. Eur. Neuropsychopharmacol. 4: 93-102.
28. Sales, G.D. and Pye, J.D. 1974. Ultrasonic communication by animals. pp. 149-231. Chapman and Hall, London.
29. Sales, G.D., Cagiano, R., De Salvia, A.M., Colonna, M., Racagni, G., and Cuomo, V. 1986. Ultrasonic vocalization in rodents: Biological aspects and effects of benzodiazepines in some experimental situations. pp. 87-92. In: GABA and Endocrine Function (Racagni, G. and Donoso, A.O. eds.), Raven Press, New York.
30. Sewell, G.D. 1970. Ultrasonic communication in rodents. Nature 227: 410.
31. Smotherman, W.P., Bell, R.W., Starzec, I., Elias, J., and Zachman, T.A. 1974. Maternal responses to infant vocalizations and olfactory cues in rats and mice. Behav. Biol. 12: 55-66.
32. Takahashi, L.K., Thomas, D.A., and Barfield, R.J. 1983. Analysis of ultrasonic vocalizations emitted by residents during aggressive encounters among rats (Rattus norvegicus). J. Comp. Psychol. 97: 207-212.
33. Takeuchi, H. and Kawashima, S. 1986. Ultrasonic vocalizations and aggressive behavior in male rats. Physiol. Behav. 38: 545-550.
34. Tonoue, T., Ashida, Y., Makino, H., and Hata, H. 1986. Inhibition of shock-elicited ultrasonic vocalization by opioid peptide in the rat: A psychotropic effect. Psychoneuroendocrinol. 11: 177-184.
35. Tonoue, T., Iwasawa, H., and Naito, H. 1987. Diazepam and endorphin independently inhibit ultrasonic distress calls in rats. Eur. J. Pharmacol. 142: 133-136.
36. Van der Poel, A.M., Noach, E.J.K., and Miczek, K.A. 1989. Temporal patterning of ultrasonic distress calls in the adult rat: Effects of morphine and benzodiazepines. Psychopharmacology 97: 147-148.
37. Vivian, J.A. and Miczek, K.A. 1990. Opioid suppression of distress ultrasounds after social defeat in rats. Neurosci. Abs. 16: 443.
38. 3 subtype-selective agonists and antagonists. Psychopharmacology 105: 513-520.
39. Winslow, J.T. and Insel, T.R. 1991b. Infant rat separation is a sensitive test for novel anxiolytics. Prog. Neuropsychopharmacol. Biol. Psychiat. 15: 745-757.