Development and Validation of an Ion-Exclusion Chromatographic Method for the Quantitation of Organic Acids in Complex Pharmaceutical Products

Journal of Chromatographic Science

Volumn 36, Issue 4, 1998, Pages 179-186

  Jenke, Dennis R ^a  

^a BAXTER HEALTHCARE CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; ACID; DRUG; LACTIC ACID DERIVATIVE; MALIC ACID DERIVATIVE;

ARTICLE; GEL CHROMATOGRAPHY; PH; REPRODUCIBILITY; ULTRAVIOLET SPECTROPHOTOMETRY;

ACETATES; ACIDS; CHROMATOGRAPHY, GEL; HYDROGEN-ION CONCENTRATION; LACTATES; MALATES; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032042318     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/36.4.179     Document Type: Article

References (17)

1. B.S. Lord and R.W. Stringham. Liquid chromatographic determination of organic acids used as pharmaceutical counterions. Anal. Chem. 68: 1067-70 (1996).
2. H. Itoh and Y. Shinbori. Simultaneous determinations of inorganic and organic acids by ion chromatography. Bull. Chem. Soc. Jpn. 60: 1327-32 (1987).
3. R.D. Rocklin, R.W. Slingsby, and C.A. Pohl. Separation and detection of carboxylic acids by ion chromatography. J. Liq. Chromatogr. 9: 757-75 (1986).
4. B.P. Downey and D.R. Jenke. Determination of oxalate in pharmaceutical matrices by indirect photometric chromatography. J. Chromatogr. Sci. 25: 519-24 (1987).
5. J.S. Fritz. Principles and applications of ion exclusion chromatography. J. Chromatogr. 546: 111-18 (1991).
6. K. Fischer, C. Corsten, P. Leidmann, D. Bieniek, and A. Kettrup. Determination of short-chain aliphatic acids in silage effluents by ion exclusion chromatography. Chromatographia 38: 43-51 (1994).
7. H.F. Botte and L. Joergensen. Evaluation of low-conductance eluents for suppressed ion exclusion chromatography. J. Chromatogr. 602: 27-31 (1992).
8. C.A. Accorsi and G. Blo. Determination of volatile and non-volatile organic acids in technical sugar solutions by ion exclusion chromatography. J. Chromatogr. 555: 65-71 (1991).
9. S.R. Bachman and M.E. Peden. Determination of organic acid anions in precipitation by ion chromatography. Water Air Soil Pollut. 33: 191-98 (1987).
10. M.J. Lesh, E.L. Wilkinson, M.R. Zolfaghari, and M.A. Schreiber. High performance liquid chromatographic analysis of lactic and lactic acid lactate in amrinone lactate formulations. J. Liq. Chromatogr. 16: 2415-22 (1993).
11. B.L. De Backer and L.J. Nagels. Potentiometric detection of organic acids in ion exclusion chromatography using different types of liquid-membrane electrodes. Anal. Chim. Acta 290: 259-67 (1994).
12. M. Ye, K. Hill, and R. Walkup. Determination of carboxylic acids by ion exclusion chromatography with non-suppressed conductivity and optical detectors. Chromatographia 35: 139-41 (1993).
13. D.W. Togami, L.G. Treat-Clemons, and D.J. Hometchko. Separation of organic acids in food products. Int. Lab. 20: 29,30,32,33 (1990).
14. D. Grosjean, A. Van Neste, and S.S. Parmer. Analysis of atmospheric carboxylic acids using single column ion exclusion chromatography with ultra-violet detection. J. Liq. Chromatogr. 12: 3007-17 (1989).
15. E. Debesis, J.P. Boehlert, T.E. Givand, and J.C. Sheridan. Submitting HPLC methods to the compendia and regulatory agencies. Pharm. Technol. 6: 120-37 (1982).
16. J.C. Wahlich and G.P. Carr. A practical approach to method validation in pharmaceutical analysis. J. Pharm. Biomed. Anal. 8: 619-23 (1990).
17. H.B.S. Conacher. Validation of methods used in crisis situations: Task force report. JAOAC 73: 332-34 (1990).